ATE165094T1 - Zytotoxische verbindungen - Google Patents

Zytotoxische verbindungen

Info

Publication number
ATE165094T1
ATE165094T1 AT94300778T AT94300778T ATE165094T1 AT E165094 T1 ATE165094 T1 AT E165094T1 AT 94300778 T AT94300778 T AT 94300778T AT 94300778 T AT94300778 T AT 94300778T AT E165094 T1 ATE165094 T1 AT E165094T1
Authority
AT
Austria
Prior art keywords
compounds
cytotoxic compounds
mpta
antitumor
formulae
Prior art date
Application number
AT94300778T
Other languages
English (en)
Inventor
Jun-Ichi Tanaka
Tatsuo Higa
Khanit Suwanoborirux
Charles William Jefford
Gerald Bernardinelli
Dolores Garcia Gravalos
Original Assignee
Pharma Mar Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharma Mar Sa filed Critical Pharma Mar Sa
Application granted granted Critical
Publication of ATE165094T1 publication Critical patent/ATE165094T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/11—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/02—1,2-Dioxanes; Hydrogenated 1,2-dioxanes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Cephalosporin Compounds (AREA)
AT94300778T 1993-02-03 1994-02-02 Zytotoxische verbindungen ATE165094T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939302044A GB9302044D0 (en) 1993-02-03 1993-02-03 Cytotoxic compounds i

Publications (1)

Publication Number Publication Date
ATE165094T1 true ATE165094T1 (de) 1998-05-15

Family

ID=10729726

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94300778T ATE165094T1 (de) 1993-02-03 1994-02-02 Zytotoxische verbindungen

Country Status (11)

Country Link
US (1) US5449684A (de)
EP (1) EP0610076B1 (de)
JP (1) JPH0769884A (de)
AT (1) ATE165094T1 (de)
AU (1) AU674366B2 (de)
CA (1) CA2114777A1 (de)
DE (1) DE69409553T2 (de)
DK (1) DK0610076T3 (de)
ES (1) ES2116522T3 (de)
GB (1) GB9302044D0 (de)
ZA (1) ZA94746B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6541515B2 (en) * 2000-08-09 2003-04-01 Merck & Co., Inc. HIV integrase inhibitors
KR102491180B1 (ko) 2017-04-27 2023-01-20 파르마 마르 에스.에이. 항종양 화합물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4731377A (en) * 1986-01-31 1988-03-15 Harbor Branch Oceanographic Institute, Inc. Antitumor cyclic peroxides
US5183924A (en) * 1989-01-24 1993-02-02 Lipha, Lyonnaise Industrielle Pharmaceutique Derivatives of benzocycloalkenyldihydroxyalkanoic acids, processes of preparation and medications containing them

Also Published As

Publication number Publication date
EP0610076B1 (de) 1998-04-15
DE69409553D1 (de) 1998-05-20
US5449684A (en) 1995-09-12
EP0610076A1 (de) 1994-08-10
CA2114777A1 (en) 1994-08-04
GB9302044D0 (en) 1993-03-24
DE69409553T2 (de) 1998-10-15
JPH0769884A (ja) 1995-03-14
ES2116522T3 (es) 1998-07-16
DK0610076T3 (da) 1999-01-25
ZA94746B (en) 1994-09-29
AU5491094A (en) 1994-08-11
AU674366B2 (en) 1996-12-19

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee