ATE165338T1 - L-carnitin salz und dieses enthaltende zusammensetzungen - Google Patents

L-carnitin salz und dieses enthaltende zusammensetzungen

Info

Publication number: ATE165338T1
Authority: AT; Austria
Prior art keywords: compositions containing; containing same; carnitine; carnitine salt; salt
Prior art date: 1994-06-20

Application number

AT95109027T

Other languages

English (en)

Inventor

Claudio Cavazza

Paolo Cavazza

Original Assignee

Avantgarde Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-06-20

Filing date

1995-06-12

Publication date

1998-05-15

1995-06-12 Application filed by Avantgarde Spa filed Critical Avantgarde Spa

1998-05-15 Application granted granted Critical

1998-05-15 Publication of ATE165338T1 publication Critical patent/ATE165338T1/de

Links

PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical class C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 2
239000000203 mixture Substances 0.000 title 1
CGALRBHTEZSWGM-SSDOTTSWSA-N (3r)-3-(2-hydroxyacetyl)oxy-4-(trimethylazaniumyl)butanoate Chemical compound C[N+](C)(C)C[C@@H](CC([O-])=O)OC(=O)CO CGALRBHTEZSWGM-SSDOTTSWSA-N 0.000 abstract 1
239000002775 capsule Substances 0.000 abstract 1
239000006187 pill Substances 0.000 abstract 1
239000000843 powder Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000008247 solid mixture Substances 0.000 abstract 1
-1 troches Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Birds (AREA)
Dermatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Diabetes (AREA)
Obesity (AREA)
Zoology (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cosmetics (AREA)

AT95109027T 1994-06-20 1995-06-12 L-carnitin salz und dieses enthaltende zusammensetzungen ATE165338T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITRM940396A IT1272290B (it)	1994-06-20	1994-06-20	Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee

Publications (1)

Publication Number	Publication Date
ATE165338T1 true ATE165338T1 (de)	1998-05-15

Family

ID=11402602

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95109027T ATE165338T1 (de)	1994-06-20	1995-06-12	L-carnitin salz und dieses enthaltende zusammensetzungen

Country Status (13)

Country	Link
US (1)	US5591450A (de)
EP (2)	EP0688761A2 (de)
JP (2)	JPH0827081A (de)
KR (2)	KR960000855A (de)
AT (1)	ATE165338T1 (de)
CA (2)	CA2150407A1 (de)
DE (1)	DE69502147T2 (de)
ES (1)	ES2116651T3 (de)
HK (1)	HK1004918A1 (de)
IT (1)	IT1272290B (de)
PH (1)	PH31606A (de)
TW (1)	TW300881B (de)
ZA (2)	ZA955024B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1272290B (it) *	1994-06-20	1997-06-16	Avantgarde Spa	Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee
AUPN115095A0 (en) *	1995-02-15	1995-03-09	Butt, Henry Lawrence	Analysis of and compositions and methods for the treatment of disease
IT1276253B1 (it)	1995-12-15	1997-10-27	Sigma Tau Ind Farmaceuti	Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi
IT1289974B1 (it) *	1997-02-25	1998-10-19	Aldo Fassi	Procedimento per la produzione di sali stabili e non igroscopici di l(-)carnitina e di alcanoli l(-)-carnitine
IT1291113B1 (it) *	1997-03-20	1998-12-29	Sigma Tau Ind Farmaceuti	Composizione nutritiva terapeutica per soggetti affetti da diabete mellito
US6080788A (en) *	1997-03-27	2000-06-27	Sole; Michael J.	Composition for improvement of cellular nutrition and mitochondrial energetics
US5863940A (en)	1997-12-01	1999-01-26	Sigma-Tau Healthscience S.P.A.	Medicament and therapeutical method for treating idiopathic asthenozoospermia
US6090848A (en) *	1997-12-01	2000-07-18	Sigma-Tau Healthscience S.P.A.	Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans
DK0951909T4 (da)	1998-03-19	2011-01-24	Sigma Tau Ind Farmaceuti	Kombinationspræparat omfattende en L-carnitin eller en alkanoyl-L-carnitin, en glycosaminoglycan og/eller bestanddel deraf
KR20000050756A (ko) *	1999-01-14	2000-08-05	연규	핀 귀걸이의 제조방법과 그 제품의 구조
US6090849A (en) *	1999-03-23	2000-07-18	The Board Of Regents For Oklahoma State University	Carnitine supplemented diet to prevent sudden death syndrome in breeder type poultry
ITRM20010364A1 (it) *	2001-06-25	2002-12-27	Biosalts Srl	Ascorbil derivati di carnitine e composizioni cosmetiche contenenti tali derivati.
EP1610760A4 (de) *	2003-03-28	2008-01-09	Lonza Ag	Topische l-carnitin-zusammensetzungen
JP4539096B2 (ja) *	2004-01-16	2010-09-08	日油株式会社	油性成分被覆ｌ−カルニチン塩粉末およびその用途
CN1322860C (zh) *	2004-08-31	2007-06-27	北京正大绿洲医药科技有限公司	左旋肉碱滴丸及其制备方法
US7572832B2 (en) *	2007-03-19	2009-08-11	Biolink Life Sciences, Inc.	Non-hygroscopic L-carnitine salts
KR101633846B1 (ko)	2013-11-25	2016-06-27	주식회사 엘지화학	도전성 패턴 형성용 조성물 및 도전성 패턴을 갖는 수지 구조체
US10118911B2 (en) *	2015-03-27	2018-11-06	Jiangsu Hengrui Medicine Co., Ltd.	P-toluenesulfonate for MEK kinase inhibitor, and crystal form thereof and preparation method therefor
CN107216339B (zh) *	2016-03-22	2021-05-04	中国科学院上海药物研究所	一种dppiv抑制剂马来酸盐的多晶型及其制备方法
CN107216340B (zh) *	2016-03-22	2021-05-04	中国科学院上海药物研究所	一种dppiv抑制剂的盐型及其制备方法
SE542106C2 (en) *	2016-08-26	2020-02-25	Atif M Dabdoub	Dietary macro/micronutritional supplement for patients undergoing kidney dialysis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0150688B1 (de)	1983-12-28	1987-04-22	Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.	Salze von L-Carnitin und Alkanoyl-L-Carnitinen sowie Verfahren zur Herstellung derselben
FR2627385B3 (fr) *	1988-02-23	1991-08-23	Serobiologiques Lab Sa	Composition notamment utile comme matiere de base pour la preparation de compositions pharmaceutiques, notamment dermatologiques et/ou cosmetiques
US4968719A (en) *	1989-04-03	1990-11-06	Sigma Tau, Industrie Farmaceutiche Riunite Spa	Method for treating vascular disease
US5137910A (en) *	1989-05-05	1992-08-11	C.D. Searle & Co.	Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders
IT1263013B (it) *	1992-10-20	1996-07-23	Avantgarde Spa	Esteri della l-carnitina e di alcanoil l-carnitine con l'acido glicolico o suoi esteri e composizioni farmaceutiche contenenti tali per il trattamento di affezioni cutanee.
IT1261984B (it) *	1993-06-22	1996-06-11	Avantgarde Spa	Uso di esteri della l-carnitina o di acil l- carnitine con idrossiacidi per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee.
IT1272290B (it) *	1994-06-20	1997-06-16	Avantgarde Spa	Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee

1994
- 1994-06-20 IT ITRM940396A patent/IT1272290B/it active IP Right Grant
1995
- 1995-05-18 EP EP95830209A patent/EP0688761A2/de not_active Withdrawn
- 1995-05-29 CA CA002150407A patent/CA2150407A1/en not_active Abandoned
- 1995-06-02 KR KR1019950014607A patent/KR960000855A/ko not_active Withdrawn
- 1995-06-07 US US08/473,208 patent/US5591450A/en not_active Expired - Fee Related
- 1995-06-12 ES ES95109027T patent/ES2116651T3/es not_active Expired - Lifetime
- 1995-06-12 DE DE69502147T patent/DE69502147T2/de not_active Expired - Fee Related
- 1995-06-12 EP EP95109027A patent/EP0697397B1/de not_active Expired - Lifetime
- 1995-06-12 AT AT95109027T patent/ATE165338T1/de not_active IP Right Cessation
- 1995-06-13 PH PH50702A patent/PH31606A/en unknown
- 1995-06-16 KR KR1019950015962A patent/KR960000217A/ko not_active Withdrawn
- 1995-06-16 CA CA002152005A patent/CA2152005A1/en not_active Abandoned
- 1995-06-19 ZA ZA955024A patent/ZA955024B/xx unknown
- 1995-06-19 JP JP7151457A patent/JPH0827081A/ja active Pending
- 1995-06-19 ZA ZA955025A patent/ZA955025B/xx unknown
- 1995-06-20 JP JP7153148A patent/JPH0826984A/ja active Pending
- 1995-06-20 TW TW084106325A patent/TW300881B/zh active
1998
- 1998-05-09 HK HK98104024A patent/HK1004918A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
ZA955024B (en)	1996-02-08
KR960000855A (ko)	1996-01-25
JPH0827081A (ja)	1996-01-30
JPH0826984A (ja)	1996-01-30
ES2116651T3 (es)	1998-07-16
EP0697397B1 (de)	1998-04-22
ITRM940396A0 (it)	1994-06-20
CA2150407A1 (en)	1995-12-21
IT1272290B (it)	1997-06-16
EP0688761A3 (de)	1996-01-17
EP0697397A1 (de)	1996-02-21
HK1004918A1 (en)	1998-12-11
US5591450A (en)	1997-01-07
ITRM940396A1 (it)	1995-12-20
ZA955025B (en)	1996-02-08
DE69502147T2 (de)	1998-08-13
DE69502147D1 (de)	1998-05-28
KR960000217A (ko)	1996-01-25
TW300881B (de)	1997-03-21
PH31606A (en)	1998-11-03
EP0688761A2 (de)	1995-12-27
CA2152005A1 (en)	1995-12-21

Legal Events

Date	Code	Title	Description
1998-10-15	UEP	Publication of translation of european patent specification
2000-03-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE165338T1 (de)	1998-05-15	L-carnitin salz und dieses enthaltende zusammensetzungen
HUP0100394A3 (en)	2002-05-28	2-phenyl substituted imidazotriazinones, process for their preparation and pharmaceutical compositions thereof
RU93005350A (ru)	1996-07-20	Новые замещенные фенилимидазолидины, способ их получения, их применение в качестве медикаментов и включающие их фармацевтические соединения
TR200200785T2 (tr)	2002-09-23	8-Fenil-6,9-dihidro-[1,2,4] triazolo [3,4-i] purin-5-on türevleri
IL86827A (en)	1993-02-21	Press coated tablets containing dihydropyridines and their preparation
IL133831A0 (en)	2001-04-30	Pharmaceutical compositions containing proteasome inhibitors
IL119488A (en)	2001-01-11	Substituted 2, 4-imidazolidinediones, their production and pharmaceutical compositions containing them
IL117091A0 (en)	1996-06-18	Methylphenyloxazolidinone derivatives pharmaceutical compositions containing the same and processes for the preparation thereof
ZA942131B (en)	1995-04-05	Pyridothiadiazines processes for their preparation and the pharmaceutical compositions which contain them
HUP9802757A3 (en)	2000-03-28	New naphthalene compounds, a process for their preparation and pharmaceutical compositions containing them
TW200716550A (en)	2007-05-01	Pharmaceutical composition comprising ritonavir
GB9014136D0 (en)	1990-08-15	Tricyclo compounds,a process for their production and a pharmaceutical composition containing the same
MY120683A (en)	2005-11-30	New phenylamidine derivatives, processes for their preparation and their use as pharmaceuticals.
CA2234480A1 (en)	1998-10-11	Colchicine and thiocolchicine derivatives with antiinflammatory and muscle relaxant activities
HUP9800512A3 (en)	1998-12-28	Salts of bismuthum and antibiotica of the moenomycin group, process for producing them, their use and pharmaceutical compositions containing them
ATE166647T1 (de)	1998-06-15	Bis-naphthalimide für die behandlung von krebs
IL99294A0 (en)	1992-07-15	Indolonaphthyridines,their production and pharmaceutical compositions containing them
FI954931L (fi)	1995-11-20	Uusia piperidinyylitioindolin johdannaisia, niiden valmistusmenetelmä, niitä sisältäviä farmaseuttisia koostumuksia, jotka ovat käyttökelpoisia erityisesti kivun lievittäjinä
EP0515995A3 (en)	1993-07-21	N-(5-thioxo-l-prolyl)-l-cysteine, derivatives thereof, processes for the preparation thereof and pharmaceutical compositions containing them
UA41981C2 (uk)	2001-10-15	Біотинові сполуки, спосіб їх отримання, фармацевтична композиція та спосіб її отримання
IL91864A0 (en)	1990-06-10	Pharmaceutical compositions containing 4-bitrophenyl-dihydropyridine amides,certain such novel compounds and their preparation
DE3064069D1 (en)	1983-08-18	(-)-alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-2-pyridineacetamide and pharmacologically acceptable salts thereof, process for the production thereof and compositions containing the same
DE69220586D1 (de)	1997-08-07	Polyaminzusammensetzungen, die sekundäre Aminogruppen enthalten
HU9803014D0 (en)	1999-02-01	Novel phtalazine derivatives, process for their production and pharmaceutical compositions containing the same
GB9014681D0 (en)	1990-08-22	Tricyclo compounds,a process for their production and a pharmaceutical composition containing the same