ATE166046T1 - Cyclohexanderivate als kaliumkanalaktivatoren - Google Patents
Cyclohexanderivate als kaliumkanalaktivatorenInfo
- Publication number
- ATE166046T1 ATE166046T1 AT94114467T AT94114467T ATE166046T1 AT E166046 T1 ATE166046 T1 AT E166046T1 AT 94114467 T AT94114467 T AT 94114467T AT 94114467 T AT94114467 T AT 94114467T AT E166046 T1 ATE166046 T1 AT E166046T1
- Authority
- AT
- Austria
- Prior art keywords
- potassium channel
- channel activators
- cyclohexane derivatives
- chem
- optionally substituted
- Prior art date
Links
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical class C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 title 1
- 239000004036 potassium channel stimulating agent Substances 0.000 title 1
- 125000000113 cyclohexyl group Chemical class [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 102000004257 Potassium Channel Human genes 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 108020001213 potassium channel Proteins 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 229910052717 sulfur Chemical group 0.000 abstract 1
- 239000011593 sulfur Chemical group 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23453893 | 1993-09-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE166046T1 true ATE166046T1 (de) | 1998-05-15 |
Family
ID=16972600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94114467T ATE166046T1 (de) | 1993-09-21 | 1994-09-14 | Cyclohexanderivate als kaliumkanalaktivatoren |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US5478839A (de) |
| EP (1) | EP0644182B1 (de) |
| KR (1) | KR0149066B1 (de) |
| CN (1) | CN1100031C (de) |
| AT (1) | ATE166046T1 (de) |
| AU (1) | AU686642B2 (de) |
| CA (1) | CA2131749A1 (de) |
| DE (1) | DE69410198T2 (de) |
| FI (1) | FI107155B (de) |
| HU (1) | HU221198B1 (de) |
| NO (1) | NO302234B1 (de) |
| NZ (1) | NZ264480A (de) |
| RU (1) | RU2129113C1 (de) |
| ZA (1) | ZA947146B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1054877A1 (de) * | 1998-02-11 | 2000-11-29 | Du Pont Pharmaceuticals Company | Cyclische sulfonamid-derivate als metallprotease-inhibitoren |
| RU2220178C1 (ru) * | 2002-08-09 | 2003-12-27 | Общество с ограниченной ответственностью "Фирма "Вивана" | Ударогасящее покрытие |
| JP4838537B2 (ja) * | 2005-05-25 | 2011-12-14 | 株式会社 資生堂 | 不全角化抑制剤、毛穴縮小剤又は肌荒れ防止・改善剤及び皮膚外用組成物 |
| EP2089389A2 (de) | 2006-11-01 | 2009-08-19 | Bristol-Myers Squibb Company | Heterocyclische verbindungen als modulatoren der glucocorticoidrezeptor,- ap1- und/oder nf-kappa-b-aktivität |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU414254A1 (de) * | 1972-09-28 | 1974-02-05 | ||
| US4200640A (en) * | 1976-04-02 | 1980-04-29 | Chugai Seiyaku Kabushiki Kaisha | Nitric ester of N-(2-hydroxyethyl)nicotinamide and pharmaceutical use |
| JPS60189291A (ja) * | 1984-03-09 | 1985-09-26 | 株式会社日立製作所 | 電子部品の自動插入装置 |
| GB9000342D0 (en) * | 1990-01-08 | 1990-03-07 | May & Baker Ltd | New compositions of matter |
| GB9002879D0 (en) * | 1990-02-08 | 1990-04-04 | May & Baker Ltd | New compositions of matter |
| KR970011277B1 (ko) * | 1991-10-14 | 1997-07-09 | 에자이 가부시키가이샤 | 티오포름아미드 유도체 |
-
1994
- 1994-09-02 US US08/300,201 patent/US5478839A/en not_active Expired - Lifetime
- 1994-09-07 AU AU71696/94A patent/AU686642B2/en not_active Ceased
- 1994-09-09 CA CA002131749A patent/CA2131749A1/en not_active Abandoned
- 1994-09-12 FI FI944207A patent/FI107155B/fi not_active IP Right Cessation
- 1994-09-14 AT AT94114467T patent/ATE166046T1/de not_active IP Right Cessation
- 1994-09-14 DE DE69410198T patent/DE69410198T2/de not_active Expired - Lifetime
- 1994-09-14 EP EP94114467A patent/EP0644182B1/de not_active Expired - Lifetime
- 1994-09-15 ZA ZA947146A patent/ZA947146B/xx unknown
- 1994-09-17 KR KR1019940023821A patent/KR0149066B1/ko not_active Expired - Fee Related
- 1994-09-19 NZ NZ264480A patent/NZ264480A/en unknown
- 1994-09-19 NO NO943472A patent/NO302234B1/no unknown
- 1994-09-20 CN CN94117892A patent/CN1100031C/zh not_active Expired - Fee Related
- 1994-09-20 HU HU9402702A patent/HU221198B1/hu not_active IP Right Cessation
- 1994-09-20 RU RU94033470A patent/RU2129113C1/ru not_active IP Right Cessation
-
1995
- 1995-09-19 US US08/531,201 patent/US5605907A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5605907A (en) | 1997-02-25 |
| AU7169694A (en) | 1995-04-06 |
| HU221198B1 (en) | 2002-08-28 |
| FI944207A7 (fi) | 1995-03-22 |
| US5478839A (en) | 1995-12-26 |
| CA2131749A1 (en) | 1995-03-22 |
| RU2129113C1 (ru) | 1999-04-20 |
| EP0644182A1 (de) | 1995-03-22 |
| EP0644182B1 (de) | 1998-05-13 |
| CN1106380A (zh) | 1995-08-09 |
| DE69410198D1 (de) | 1998-06-18 |
| KR0149066B1 (ko) | 1998-10-15 |
| HUT68036A (en) | 1995-05-29 |
| NO943472D0 (no) | 1994-09-19 |
| NO302234B1 (no) | 1998-02-09 |
| RU94033470A (ru) | 1996-08-10 |
| CN1100031C (zh) | 2003-01-29 |
| NO943472L (no) | 1995-03-22 |
| FI107155B (fi) | 2001-06-15 |
| KR950008446A (ko) | 1995-04-17 |
| HU9402702D0 (en) | 1994-12-28 |
| DE69410198T2 (de) | 1999-03-11 |
| ZA947146B (en) | 1996-03-15 |
| FI944207A0 (fi) | 1994-09-12 |
| AU686642B2 (en) | 1998-02-12 |
| NZ264480A (en) | 1995-07-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |