ATE166872T1 - Benzothiazol-derivate - Google Patents

Benzothiazol-derivate

Info

Publication number: ATE166872T1
Authority: AT; Austria
Prior art keywords: alkyl; hydrogen; acyl; present; benzothiazole derivatives
Prior art date: 1995-03-28

Application number

AT96104980T

Other languages

English (en)

Inventor

Hiroki Muramoto

Kiyoshi Fukuda

Taisuke Hasegawa

Kaoru Okamoto

Takayuki Kotani

Original Assignee

Nippon Zoki Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-28

Filing date

1996-03-28

Publication date

1998-06-15

1996-03-28 Application filed by Nippon Zoki Pharmaceutical Co filed Critical Nippon Zoki Pharmaceutical Co

1998-06-15 Application granted granted Critical

1998-06-15 Publication of ATE166872T1 publication Critical patent/ATE166872T1/de

Links

IOJUPLGTWVMSFF-UHFFFAOYSA-N benzothiazole Chemical class C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 title abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 7
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
125000002252 acyl group Chemical group 0.000 abstract 3
DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical group CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 2
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
239000003814 drug Substances 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical group 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
102000007330 LDL Lipoproteins Human genes 0.000 abstract 1
108010007622 LDL Lipoproteins Proteins 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
235000012000 cholesterol Nutrition 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
201000005577 familial hyperlipidemia Diseases 0.000 abstract 1
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
150000002632 lipids Chemical class 0.000 abstract 1
-1 nitro, amino Chemical group 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT96104980T 1995-03-28 1996-03-28 Benzothiazol-derivate ATE166872T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP9630095		1995-03-28

Publications (1)

Publication Number	Publication Date
ATE166872T1 true ATE166872T1 (de)	1998-06-15

Family

ID=14161189

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96104980T ATE166872T1 (de)	1995-03-28	1996-03-28	Benzothiazol-derivate

Country Status (9)

Country	Link
US (1)	US5900426A (de)
EP (1)	EP0735029B1 (de)
KR (1)	KR100431789B1 (de)
CN (1)	CN1063443C (de)
AT (1)	ATE166872T1 (de)
AU (1)	AU695925B2 (de)
CA (1)	CA2172879A1 (de)
DE (1)	DE69600329T2 (de)
TW (1)	TW438786B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9804212D0 (sv) *	1998-12-04	1998-12-04	Astra Pharma Prod	Compounds
JP2005500313A (ja) *	2001-06-22	2005-01-06	ファイザー・プロダクツ・インク	基材中の低可溶性薬物の固体分散体および溶解度向上性ポリマーを含有する医薬品組成物
JP6012468B2 (ja)	2009-10-02	2016-10-25	アヴェクシンエーエス	抗炎症性２−オキソチアゾールおよび２−オキソオキサゾール
WO2012025638A1 (en)	2010-08-27	2012-03-01	Universität des Saarlandes	Selective 17beta-hydroxysteroid dehydrogenase type 1 inhibitors
CN105102438B (zh)	2013-01-29	2019-04-30	埃维克辛公司	抗炎症和抗肿瘤的2-氧代噻唑类和2-氧代噻吩类化合物
GB201413695D0 (en)	2014-08-01	2014-09-17	Avexxin As	Compound
GB201604318D0 (en)	2016-03-14	2016-04-27	Avexxin As	Combination therapy
CN115504942A (zh) *	2022-09-15	2022-12-23	汕头大学	一种烷基或酰基取代苯并噻唑类衍生物的合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE786520A (fr) *	1971-07-23	1973-01-22	Bayer Ag	Nouveaux benzothiazoles substitues, leur preparation et leur application comme fongicides et bactericides
JPS5371071A (en) *	1976-12-08	1978-06-24	Teijin Ltd	Alpha-phenoxyacetic acid derivs.
DE2950095A1 (de) *	1979-12-13	1981-06-19	Merck Patent Gmbh, 6100 Darmstadt	Benzothiazolderivate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
JPS5936670A (ja) *	1982-08-25	1984-02-28	Takeda Chem Ind Ltd	ベンゾチアゾ−ル誘導体，その製造法およびそれを含有する摂食抑制剤
JPS62294238A (ja) *	1986-06-13	1987-12-21	Fuji Photo Film Co Ltd	感光性組成物
GB2209830A (en) *	1987-09-04	1989-05-24	Electricity Council	Temperature sensing apparatus
EP0388682A1 (de) *	1989-03-15	1990-09-26	Bayer Ag	Substituierte Heteroarylphenylether, Verfahren zu ihrer Herstellung und ihre Verwendung als Insektizide
EP0412570B1 (de) *	1989-08-11	1996-07-10	Fuji Photo Film Co., Ltd.	Licht- und wärmeempfindliches Aufzeichnungsmaterial
ATE167473T1 (de) *	1990-08-20	1998-07-15	Eisai Co Ltd	Sulfonamid-derivate
ATE159251T1 (de) *	1990-08-29	1997-11-15	Upjohn Co	Tropolonderivate und pharmazeutische zubereitungen davon zur vorbeugung und behandlung von ischämischen krankheiten
JPH04128722A (ja) *	1990-09-19	1992-04-30	Fuji Electric Co Ltd	非線形光学材料

1996
- 1996-03-27 TW TW085103692A patent/TW438786B/zh not_active IP Right Cessation
- 1996-03-27 US US08/624,746 patent/US5900426A/en not_active Expired - Fee Related
- 1996-03-27 CN CN96103387A patent/CN1063443C/zh not_active Expired - Fee Related
- 1996-03-28 KR KR1019960008925A patent/KR100431789B1/ko not_active Expired - Fee Related
- 1996-03-28 AU AU50572/96A patent/AU695925B2/en not_active Ceased
- 1996-03-28 DE DE69600329T patent/DE69600329T2/de not_active Expired - Fee Related
- 1996-03-28 AT AT96104980T patent/ATE166872T1/de not_active IP Right Cessation
- 1996-03-28 CA CA002172879A patent/CA2172879A1/en not_active Abandoned
- 1996-03-28 EP EP96104980A patent/EP0735029B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US5900426A (en)	1999-05-04
DE69600329T2 (de)	1998-11-05
TW438786B (en)	2001-06-07
CN1137524A (zh)	1996-12-11
AU695925B2 (en)	1998-08-27
DE69600329D1 (de)	1998-07-09
KR960035779A (ko)	1996-10-28
AU5057296A (en)	1996-10-10
EP0735029A1 (de)	1996-10-02
CA2172879A1 (en)	1996-09-29
EP0735029B1 (de)	1998-06-03
CN1063443C (zh)	2001-03-21
KR100431789B1 (ko)	2004-08-30

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Legal Events

Date	Code	Title	Description
1998-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties