ATE167182T1 - (pyrrolidinyl)phenylcarbamate und zwischenverbindungen, verfahren zu ihrer herstellung und ihre verwendung als medikamente - Google Patents

(pyrrolidinyl)phenylcarbamate und zwischenverbindungen, verfahren zu ihrer herstellung und ihre verwendung als medikamente

Info

Publication number
ATE167182T1
ATE167182T1 AT95103149T AT95103149T ATE167182T1 AT E167182 T1 ATE167182 T1 AT E167182T1 AT 95103149 T AT95103149 T AT 95103149T AT 95103149 T AT95103149 T AT 95103149T AT E167182 T1 ATE167182 T1 AT E167182T1
Authority
AT
Austria
Prior art keywords
pyrrolidinyl
intermediate compounds
phenylcarbamates
medications
production
Prior art date
Application number
AT95103149T
Other languages
English (en)
Inventor
David Dr Wettlaufer
Peter Allen Nemoto
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of ATE167182T1 publication Critical patent/ATE167182T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT95103149T 1994-03-10 1995-03-06 (pyrrolidinyl)phenylcarbamate und zwischenverbindungen, verfahren zu ihrer herstellung und ihre verwendung als medikamente ATE167182T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/208,554 US5338739A (en) 1994-03-10 1994-03-10 (Pyrrolidinyl)phenyl carbamates, compositions and use

Publications (1)

Publication Number Publication Date
ATE167182T1 true ATE167182T1 (de) 1998-06-15

Family

ID=22775020

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95103149T ATE167182T1 (de) 1994-03-10 1995-03-06 (pyrrolidinyl)phenylcarbamate und zwischenverbindungen, verfahren zu ihrer herstellung und ihre verwendung als medikamente

Country Status (8)

Country Link
US (3) US5338739A (de)
EP (1) EP0671388B1 (de)
JP (1) JP3453211B2 (de)
AT (1) ATE167182T1 (de)
CA (1) CA2144294C (de)
DE (1) DE69502855T2 (de)
DK (1) DK0671388T3 (de)
ES (1) ES2119244T3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19648011A1 (de) * 1996-11-20 1998-05-28 Bayer Ag Cyclische Imine
TW200418831A (en) * 2002-11-06 2004-10-01 Smithkline Beecham Corp Sulfonamides
US20060020285A1 (en) * 2004-07-22 2006-01-26 Volker Niermann Method for filtering blood in a vessel with helical elements
WO2010011302A1 (en) * 2008-07-22 2010-01-28 Chdi, Inc. Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
KR20140072037A (ko) 2011-08-30 2014-06-12 씨에이치디아이 파운데이션, 인코포레이티드 키뉴레닌-3-모노옥시게나제 억제제, 약학적 조성물 및 이의 사용 방법
SI2750677T1 (sl) 2011-08-30 2017-10-30 Chdi Foundation, Inc. Inhibitorji kinurenin-3-monooksigenaze, farmacevtski sestavki in postopki njihove uporabe
AU2015289492B2 (en) 2014-07-17 2020-02-20 Chdi Foundation, Inc. Methods and compositions for treating HIV-related disorders
US20170266157A1 (en) * 2016-03-21 2017-09-21 David Weinstein Methods for wound healing and scar prevention

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3149123A (en) * 1961-01-04 1964-09-15 Parke Davis & Co 1, 3-dialkyl-3-oxyphenylpyrrolidine compounds
CH484103A (de) * 1966-09-02 1970-01-15 Ciba Geigy Verfahren zur Herstellung von neuen Carbamaten
GB1178400A (en) * 1966-12-13 1970-01-21 Delalande Sa Nitrogen Substituted Amines and their process of Preparation.
US3674806A (en) * 1969-04-30 1972-07-04 Reynolds Tobacco Co R 1,3,3,4,4-pentasubstituted pyrrolidines
DE2413935A1 (de) * 1974-03-20 1975-10-16 Schering Ag 4-(polyalkoxy-phenyl)-2-pyrrolidone
US5001142A (en) * 1989-07-19 1991-03-19 American Cyanamid Company 1-substituted-2-(3-amino-1-propynyl)pyrrolidine derivatives
US5015741A (en) * 1989-10-03 1991-05-14 Philip Morris Incorporated Nicotine analogs
WO1992018475A2 (en) * 1991-04-17 1992-10-29 The Upjohn Company Substituted phenylazacycloalkanes as cns agents
ATE242244T1 (de) * 1991-09-26 2003-06-15 Us Gov Health & Human Serv Substituierte phenserine und phenylcarbamate von (-)-eserolin, (-)-n1-noreserolin und (-)-n1- benzylnoresorolin als spezifische acetylcholinesterase-inhibitoren

Also Published As

Publication number Publication date
CA2144294A1 (en) 1995-09-11
US5591856A (en) 1997-01-07
CA2144294C (en) 2002-11-12
EP0671388B1 (de) 1998-06-10
EP0671388A1 (de) 1995-09-13
DE69502855D1 (de) 1998-07-16
US5405845A (en) 1995-04-11
JPH07278103A (ja) 1995-10-24
DK0671388T3 (da) 1999-02-15
DE69502855T2 (de) 1998-11-26
US5338739A (en) 1994-08-16
ES2119244T3 (es) 1998-10-01
JP3453211B2 (ja) 2003-10-06

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee