ATE167195T1 - Monoessigsäure derivate der peptide leu-phe-ala und ala-leu-phe und deren verwendung in der erkennung und vernichtung von tumorzellen und virusinfizierten zellen - Google Patents

Monoessigsäure derivate der peptide leu-phe-ala und ala-leu-phe und deren verwendung in der erkennung und vernichtung von tumorzellen und virusinfizierten zellen

Info

Publication number: ATE167195T1
Authority: AT; Austria
Prior art keywords: phe; ala; leu; virus; cells
Prior art date: 1993-03-22

Application number

AT94830111T

Other languages

English (en)

Inventor

Leonida Grippa

Original Assignee

Leonida Grippa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-03-22

Filing date

1994-03-16

Publication date

1998-06-15

1994-03-16 Application filed by Leonida Grippa filed Critical Leonida Grippa

1998-06-15 Application granted granted Critical

1998-06-15 Publication of ATE167195T1 publication Critical patent/ATE167195T1/de

Links

210000004027 cell Anatomy 0.000 title abstract 3
210000004881 tumor cell Anatomy 0.000 title abstract 2
VHVVPYOJIIQCKS-QEJZJMRPSA-N Ala-Leu-Phe Chemical compound C[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 VHVVPYOJIIQCKS-QEJZJMRPSA-N 0.000 title 1
ZDBMWELMUCLUPL-QEJZJMRPSA-N Leu-Phe-Ala Chemical compound CC(C)C[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](C)C(O)=O)CC1=CC=CC=C1 ZDBMWELMUCLUPL-QEJZJMRPSA-N 0.000 title 1
239000002253 acid Substances 0.000 title 1
230000006378 damage Effects 0.000 title 1
238000001514 detection method Methods 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
206010028980 Neoplasm Diseases 0.000 abstract 1
241000700605 Viruses Species 0.000 abstract 1
230000001594 aberrant effect Effects 0.000 abstract 1
230000003213 activating effect Effects 0.000 abstract 1
239000013543 active substance Substances 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
210000000987 immune system Anatomy 0.000 abstract 1
238000009169 immunotherapy Methods 0.000 abstract 1
210000004698 lymphocyte Anatomy 0.000 abstract 1
230000001394 metastastic effect Effects 0.000 abstract 1
206010061289 metastatic neoplasm Diseases 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1
230000003612 virological effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT94830111T 1993-03-22 1994-03-16 Monoessigsäure derivate der peptide leu-phe-ala und ala-leu-phe und deren verwendung in der erkennung und vernichtung von tumorzellen und virusinfizierten zellen ATE167195T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP93830113		1993-03-22

Publications (1)

Publication Number	Publication Date
ATE167195T1 true ATE167195T1 (de)	1998-06-15

Family

ID=8215135

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94830111T ATE167195T1 (de)	1993-03-22	1994-03-16	Monoessigsäure derivate der peptide leu-phe-ala und ala-leu-phe und deren verwendung in der erkennung und vernichtung von tumorzellen und virusinfizierten zellen

Country Status (4)

Country	Link
EP (1)	EP0627444B1 (de)
AT (1)	ATE167195T1 (de)
DE (1)	DE69410881T2 (de)
ES (1)	ES2119987T3 (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1148005B (it) *	1981-04-09	1986-11-26	Leonida Grippa	Tripeptide nelle sue sei combinazioni amminoacide alania fenilalanina e leucina in particolare fenil-alanina-alanina-leucina (p-a-l) aventela proprieta' di esaltare l'immunita' antivirale ed antitumorale
FR2569111B1 (fr) *	1984-08-16	1987-04-17	Rhone Poulenc Sante	Nouveaux medicaments contenant des tripeptides
FR2610934B1 (fr) *	1987-02-13	1989-05-05	Adir	Nouveaux derives peptidiques a structure polycyclique azotee, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

1994
- 1994-03-16 AT AT94830111T patent/ATE167195T1/de active
- 1994-03-16 EP EP94830111A patent/EP0627444B1/de not_active Expired - Lifetime
- 1994-03-16 DE DE69410881T patent/DE69410881T2/de not_active Expired - Fee Related
- 1994-03-16 ES ES94830111T patent/ES2119987T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE69410881T2 (de)	1999-02-11
ES2119987T3 (es)	1998-10-16
DE69410881D1 (de)	1998-07-16
EP0627444B1 (de)	1998-06-10
EP0627444A1 (de)	1994-12-07

Similar Documents

Publication	Publication Date	Title
EA199901031A1 (ru)	2000-06-26	Производные бензимидазола
NO20014415D0 (no)	2001-09-11	Medisinske preparater til behandling av <alfa>-galaktosidase- A-defisiens
DE3866068D1 (de)	1991-12-12	Verhinderung der zahnsteinbildung durch polyanionische/hydrophobe peptide und deren derivate.
DE3689363D1 (de)	1994-01-20	Pharmazeutische Zusammensetzungen zur Behandlung der Metastasen von Krebstumoren.
IT1204914B (it)	1989-03-10	Procedimento pe la protezione di sostanze poco stabili con miscele polimeriche e processi per la loro applicazione
UA39158C2 (uk)	2001-06-15	Похідні n4-оксикарбоніл-5'-дезокси-5-фторцитидину та фармацевтичний препарат на їх основі
DE69715888D1 (de)	2002-10-31	Pyridylalken- und pyridylalkin-säureamide als cytostatika und immunosuppressive arzneimittel
DE69124274D1 (de)	1997-03-06	Oligopeptide, sie enthaltende pharmazeutische und Futterzusammensetzung und Benützung von Oligopeptiden
ATE197670T1 (de)	2000-12-15	Parenterales busulfan zur behandlung von malignen krankheiten
ATE33556T1 (de)	1988-05-15	Adenosinderivate enthaltende pharmazeutische zusammensetzung fuer behandlung von tumoren.
ATE174222T1 (de)	1998-12-15	Blockierung der anlagerung von keimen an menschliche zellen
ATE367808T1 (de)	2007-08-15	N-chlorphenylcarbamate enthaltendes arzneimittel sowie n-chlorphenylthiocarbamate zur hemmung des wachstums von viren
EA200000240A1 (ru)	2000-10-30	Соединения, препятствующие эффекту раннего превращения лекарственных средств
EA199800526A1 (ru)	1999-04-29	Производные бензимидазола и их применение для лечения вирусных инфекций
IT8548055A1 (it)	1986-11-08	Composizioni farmaceutiche per la terapia di sindromi cerebrali involutive e del decadimento mentale
RU94030808A (ru)	1996-10-20	Применение фосфокриатина или фосфоенолпировиноградной кислоты для лечения опухолей и фармацевтические препараты, обладающие противоопухолевой активностью
FR2594332B1 (fr)	1988-12-16	Derives d'acides amino-benzoiques, d'acides hydroxy-benzoiques, d'acides cinnamiques, d'acide urocanique et de benzimidazole presentant ou non un groupement d'acide amine absorbant les uvb et/ou les uva et permettant d'eviter les photodermatoses, chez l'homme, consecutives a l'administration de medicaments, a l'emploi de cosmetiques parfumes ou de parfums
EA200000242A1 (ru)	2000-08-28	Применение фанхинона для лечения болезни альцгеймера
DE69410881D1 (de)	1998-07-16	Monoessigsäure Derivate der Peptide leu-phe-ala und ala-leu-phe und deren Verwendung in der Erkennung und Vernichtung von Tumorzellen und virusinfizierten Zellen
FI961380A0 (fi)	1996-03-26	Koostumuksia virusten aiheuttamien kasvainten ehkäisemiseksi ja hoitamiseksi
ATE253944T1 (de)	2003-11-15	Synthetische peptide und diese enthaltende arzneimittel zur behandlung des systemischen lupus erythematodes
DK0845034T3 (da)	2003-06-30	Peptid med pronociceptive egenskaber
ATE90359T1 (de)	1993-06-15	Peptide.
DK520086D0 (da)	1986-10-30	Fremgangsmaade til delvis oprensning af et biologisk aktivt protein, herunder tumornekrosefaktor, samt det herved produkt og pharmaceutisk praeparat indeholdende samme
ATE311845T1 (de)	2005-12-15	Pharmazeutische und kosmetische zubereitungen enthaltend urocaninsäurederivate als antioxidationsmittel oder radikalenabfangermittel