ATE167522T1 - Monoklonale antikörper gegen mögliche hcv- hüllregionen und methoden diese zu benutzen - Google Patents

Monoklonale antikörper gegen mögliche hcv- hüllregionen und methoden diese zu benutzen

Info

Publication number
ATE167522T1
ATE167522T1 AT92906219T AT92906219T ATE167522T1 AT E167522 T1 ATE167522 T1 AT E167522T1 AT 92906219 T AT92906219 T AT 92906219T AT 92906219 T AT92906219 T AT 92906219T AT E167522 T1 ATE167522 T1 AT E167522T1
Authority
AT
Austria
Prior art keywords
monoclonal antibodies
methods
antibodies against
against possible
hcv envelope
Prior art date
Application number
AT92906219T
Other languages
English (en)
Inventor
Mary S Gibadlo
Joan D Tyner
Larry T Mimms
David S Vallari
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE167522T1 publication Critical patent/ATE167522T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/116—Togaviridae (F); Matonaviridae (F); Flaviviridae (F)
    • C07K16/118—Hepatitis C virus; GB virus C [GBV-C]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT92906219T 1991-01-31 1992-01-30 Monoklonale antikörper gegen mögliche hcv- hüllregionen und methoden diese zu benutzen ATE167522T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64847591A 1991-01-31 1991-01-31

Publications (1)

Publication Number Publication Date
ATE167522T1 true ATE167522T1 (de) 1998-07-15

Family

ID=24600936

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92906219T ATE167522T1 (de) 1991-01-31 1992-01-30 Monoklonale antikörper gegen mögliche hcv- hüllregionen und methoden diese zu benutzen

Country Status (11)

Country Link
EP (1) EP0569537B1 (de)
JP (1) JP3483555B2 (de)
KR (1) KR930703361A (de)
AT (1) ATE167522T1 (de)
AU (1) AU662517B2 (de)
CA (1) CA2101534C (de)
DE (1) DE69225960T2 (de)
DK (1) DK0569537T3 (de)
ES (1) ES2118129T3 (de)
HK (1) HK1012838A1 (de)
WO (1) WO1992013892A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0185426B1 (ko) 1991-06-24 1999-04-01 로버트 피. 블랙버언 씨형 간염 바이러스 폴리펩티드
JP3217600B2 (ja) * 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
EP1845108A3 (de) * 1994-07-29 2007-10-24 Innogenetics N.V. Monoklonale Antikörper gegen gereinigte Hüllproteine des Hepatitis-C-Virus für diagnostische und therapeutische Zwecke
EP0947525A1 (de) 1998-03-27 1999-10-06 Innogenetics N.V. Epitope in der viralen Hüllproteine und spezifische Antikörper gegen diese Epitope: Verwendung für die detektion von viralantigene im empfängergewebe
EP1295126B1 (de) * 1999-07-28 2007-01-24 Novartis Vaccines and Diagnostics, Inc. Verfahren zum nachweis von hepatitis c antigenen
US6815160B1 (en) 1999-07-28 2004-11-09 Chiron Corporation Hepatitis C viral antigen immunoassay detection systems
RS53258B (sr) 2007-02-21 2014-08-29 University Of Massachusetts Humana antitela protiv virusa hepatitisa c (hcv) i njihove upotrebe
CN101809033A (zh) 2007-07-25 2010-08-18 日本国立感染症研究所 对丙型肝炎病毒(hcv)感染具有抑制活性的抗体和其用途
DK2862876T3 (en) 2008-09-30 2016-05-23 Toray Industries Antibody binding to envelope protein 2 of hepatitis C virus and method for identifying the genotype of hepatitis C virus using the same
CN102596996B (zh) 2009-10-30 2014-06-18 东丽株式会社 对丙型肝炎病毒(hcv)具有感染抑制活性的抗体及其用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0071640B1 (de) * 1981-02-11 1986-06-04 Connaught Laboratories Incorporated Nicht-a, nicht-b hepatitisvirus
WO1989004669A1 (en) * 1987-11-18 1989-06-01 Chiron Corporation Nanbv diagnostics and vaccines
HUT54896A (en) * 1989-03-17 1991-04-29 Chiron Corp Process for producing aquous diagnosticum and vaccine of nanbv
AU638304B2 (en) * 1989-12-22 1993-06-24 Abbott Laboratories Hepatitis c assay
JPH05508762A (ja) * 1990-04-03 1993-12-09 サウスウエスト・ファウンデイション・フォー・バイオメディカル・リサーチ 精製されたｈｃｖならびにｈｃｖタンパク質およびペプチド
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
DK0770679T4 (da) * 1990-11-03 2010-05-10 Siemens Healthcare Diagnostics HCV-specifikke peptider, sammensætninger dertil og anvendelse deraf
WO1992008738A1 (en) * 1990-11-07 1992-05-29 Abbott Laboratories Monoclonal antibodies to hepatitis c virus and method for using same

Also Published As

Publication number Publication date
WO1992013892A1 (en) 1992-08-20
EP0569537A1 (de) 1993-11-18
EP0569537A4 (en) 1994-10-05
DE69225960T2 (de) 1999-01-21
KR930703361A (ko) 1993-11-29
ES2118129T3 (es) 1998-09-16
CA2101534C (en) 2004-01-20
AU662517B2 (en) 1995-09-07
AU1362792A (en) 1992-09-07
HK1012838A1 (en) 1999-08-06
DK0569537T3 (da) 1999-04-06
EP0569537B1 (de) 1998-06-17
JP3483555B2 (ja) 2004-01-06
JPH06505389A (ja) 1994-06-23
CA2101534A1 (en) 1992-08-01
DE69225960D1 (de) 1998-07-23

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee