ATE167522T1 - Monoklonale antikörper gegen mögliche hcv- hüllregionen und methoden diese zu benutzen - Google Patents

Monoklonale antikörper gegen mögliche hcv- hüllregionen und methoden diese zu benutzen

Info

Publication number
ATE167522T1
ATE167522T1 AT92906219T AT92906219T ATE167522T1 AT E167522 T1 ATE167522 T1 AT E167522T1 AT 92906219 T AT92906219 T AT 92906219T AT 92906219 T AT92906219 T AT 92906219T AT E167522 T1 ATE167522 T1 AT E167522T1
Authority
AT
Austria
Prior art keywords
monoclonal antibodies
methods
antibodies against
against possible
hcv envelope
Prior art date
Application number
AT92906219T
Other languages
English (en)
Inventor
Mary S Gibadlo
Joan D Tyner
Larry T Mimms
David S Vallari
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE167522T1 publication Critical patent/ATE167522T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/116—Togaviridae (F); Matonaviridae (F); Flaviviridae (F)
    • C07K16/118—Hepatitis C virus; GB virus C [GBV-C]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT92906219T 1991-01-31 1992-01-30 Monoklonale antikörper gegen mögliche hcv- hüllregionen und methoden diese zu benutzen ATE167522T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64847591A 1991-01-31 1991-01-31

Publications (1)

Publication Number Publication Date
ATE167522T1 true ATE167522T1 (de) 1998-07-15

Family

ID=24600936

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92906219T ATE167522T1 (de) 1991-01-31 1992-01-30 Monoklonale antikörper gegen mögliche hcv- hüllregionen und methoden diese zu benutzen

Country Status (10)

Country Link
EP (1) EP0569537B1 (de)
JP (1) JP3483555B2 (de)
KR (1) KR930703361A (de)
AT (1) ATE167522T1 (de)
AU (1) AU662517B2 (de)
CA (1) CA2101534C (de)
DE (1) DE69225960T2 (de)
DK (1) DK0569537T3 (de)
ES (1) ES2118129T3 (de)
WO (1) WO1992013892A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0185426B1 (ko) * 1991-06-24 1999-04-01 로버트 피. 블랙버언 씨형 간염 바이러스 폴리펩티드
JP3217600B2 (ja) * 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
WO1996004385A2 (en) 1994-07-29 1996-02-15 Innogenetics N.V. Purified hepatitis c virus envelope proteins for diagnostic and therapeutic use
EP0947525A1 (de) * 1998-03-27 1999-10-06 Innogenetics N.V. Epitope in der viralen Hüllproteine und spezifische Antikörper gegen diese Epitope: Verwendung für die detektion von viralantigene im empfängergewebe
CA2380777C (en) * 1999-07-28 2011-01-04 Chiron Corporation Hepatitis c viral antigen immunoassay detection systems
US6815160B1 (en) 1999-07-28 2004-11-09 Chiron Corporation Hepatitis C viral antigen immunoassay detection systems
US8551484B2 (en) 2007-02-21 2013-10-08 University Of Massachusetts Human antibodies against hepatitis C virus (HCV) and uses thereof
AU2008280057A1 (en) 2007-07-25 2009-01-29 Japan As Represented By Director-General Of National Institute Of Infectious Diseases Antibody having inhibitory activity on infection with hepatitis C virus (HCV), and use thereof
JP5608087B2 (ja) 2008-09-30 2014-10-15 東レ株式会社 Ｃ型肝炎ウイルスのエンベロープタンパク質２に結合する抗体及びそれを用いたｃ型肝炎ウイルスの遺伝子型の同定方法
US8592559B2 (en) 2009-10-30 2013-11-26 Toray Industries, Inc. Antibody having activity of inhibiting hepatitis C virus (HCV) infection and use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982002774A1 (en) * 1981-02-11 1982-08-19 Baxter Travenol Lab Non-a,non-b hepatitis virus
BR8807310A (pt) * 1987-11-18 1990-03-13 Chiron Corp Polinucleotidio,polinucleotidio recombinante,vetor recombinante,celula hospedeira,sistema de expressao recombinante,celula transformada,polipeptidio,hcv,preparacao de polipeptidio,polipeptidio de hcv,polipeptidio purificado,polipeptidio recombinante,polipeptidio de fusao,anticorpo monoclonal,preparacao purificada de anticorpos policlonais,particula,sonda de polinucleotidio,kit anticorpo para epetopo de hcv,metodo para producao de polipeptidio,metodo para deteccao de acidos nucleicos de hcv,imunoensaio para detectar antigeno de hcv,imunoensaio para detectar anticorpos dirigidos contra antigeno de hcv,vacina para tratamento de infeccao de hcv,celula,celula infectada com hcv,metodo para producao de anticorpos para hcv e metodo para isolar cdna derivado do genoma de um agente infeccioso nao identificado
HU225068B1 (en) * 1989-03-17 2006-05-29 Chiron Corp Process for producing diagnostics and vaccine of nanbh
AU638304B2 (en) * 1989-12-22 1993-06-24 Abbott Laboratories Hepatitis c assay
AU7672991A (en) * 1990-04-03 1991-10-30 Southwest Foundation For Biomedical Research Purified hcv and hcv proteins and peptides
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
ES2161682T3 (es) * 1990-11-03 2001-12-16 Dade Behring Marburg Gmbh Peptidos especificos a hcv, agentes adecuados para ellos y su utilizacion.
KR930702507A (ko) * 1990-11-07 1993-09-09 챨스 엠. 브록 C형 간염 바이러스에 대한 모노클로날 항체 및 이의 사용 방법

Also Published As

Publication number Publication date
CA2101534A1 (en) 1992-08-01
JPH06505389A (ja) 1994-06-23
AU662517B2 (en) 1995-09-07
EP0569537A4 (en) 1994-10-05
DE69225960D1 (de) 1998-07-23
EP0569537A1 (de) 1993-11-18
HK1012838A1 (en) 1999-08-06
CA2101534C (en) 2004-01-20
AU1362792A (en) 1992-09-07
WO1992013892A1 (en) 1992-08-20
ES2118129T3 (es) 1998-09-16
DK0569537T3 (da) 1999-04-06
KR930703361A (ko) 1993-11-29
EP0569537B1 (de) 1998-06-17
DE69225960T2 (de) 1999-01-21
JP3483555B2 (ja) 2004-01-06

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee