ATE167873T1 - Neue heterocyclische acyldipeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung - Google Patents

Neue heterocyclische acyldipeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung

Info

Publication number: ATE167873T1
Authority: AT; Austria
Prior art keywords: acyldipeptides; pct; group; production; pharmaceutical composition
Prior art date: 1993-04-22

Application number

AT94914681T

Other languages

English (en)

Inventor

Danijel Kikelj

Elizabeta Suhadolc

Alenka Rutar

Slavko Pecar

Alesa Puncuh

Uros Urleb

Vesna Leskovsek

Gasper Marc

Marija Sollner

Ales Krbavcic

Gregor Sersa

Srdjan Novakovic

Lucka Povsic

Anton Stalc

Original Assignee

Univ Ljubljani

Lek Tovarna Farmacevtskih

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-04-22

Filing date

1994-04-21

Publication date

1998-07-15

1994-04-21 Application filed by Univ Ljubljani, Lek Tovarna Farmacevtskih filed Critical Univ Ljubljani

1998-07-15 Application granted granted Critical

1998-07-15 Publication of ATE167873T1 publication Critical patent/ATE167873T1/de

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 3
125000000962 organic group Chemical group 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
101100516563 Caenorhabditis elegans nhr-6 gene Proteins 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
125000004429 atom Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000003308 immunostimulating effect Effects 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Genetics & Genomics (AREA)
Public Health (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AT94914681T 1993-04-22 1994-04-21 Neue heterocyclische acyldipeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung ATE167873T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SI9300212A SI9300212A (en)	1993-04-22	1993-04-22	Novel N-acyldipeptides, process for the preparation thereof and pharmaceutical composition containing the same

Publications (1)

Publication Number	Publication Date
ATE167873T1 true ATE167873T1 (de)	1998-07-15

Family

ID=20431165

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94914681T ATE167873T1 (de)	1993-04-22	1994-04-21	Neue heterocyclische acyldipeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung

Country Status (8)

Country	Link
US (1)	US5824652A (de)
EP (1)	EP0695308B1 (de)
JP (1)	JP2886987B2 (de)
AT (1)	ATE167873T1 (de)
DE (1)	DE69411380T2 (de)
ES (1)	ES2120039T3 (de)
SI (1)	SI9300212A (de)
WO (1)	WO1994024152A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2311411B1 (es) *	2007-07-19	2010-01-08	Universidad De Cadiz.	Derivados 2-alquil-2h-1, 4-benzoxacin-3(4h)-ona y 2-alcoxicarbonil-2h-1,4-benzoxacin-3(4h)-ona, con actividad fitotoxica.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2326930A1 (fr) *	1975-10-09	1977-05-06	Anvar	Agents hydrosolubles depresseurs non specifiques des reponses immunitaires
US4322341A (en) *	1980-05-13	1982-03-30	Fujisawa Pharmaceutical Co	Peptide, process for preparation thereof and use thereof
SI9011830B (sl) *	1990-09-27	1999-12-31	Univerza V Ljubljani, Fakulteta Za Farmacijo	Novi N-acildipeptidi, postopki za njihovo pripravo in farmacevtski pripravki, ki jih vsebujejo
US5321216A (en) *	1991-04-09	1994-06-14	Otis Elevator Company	Restraining elevator car motion while the doors are open

1993
- 1993-04-22 SI SI9300212A patent/SI9300212A/sl unknown
1994
- 1994-04-21 JP JP6523063A patent/JP2886987B2/ja not_active Expired - Fee Related
- 1994-04-21 ES ES94914681T patent/ES2120039T3/es not_active Expired - Lifetime
- 1994-04-21 EP EP94914681A patent/EP0695308B1/de not_active Expired - Lifetime
- 1994-04-21 DE DE69411380T patent/DE69411380T2/de not_active Expired - Fee Related
- 1994-04-21 AT AT94914681T patent/ATE167873T1/de active
- 1994-04-21 US US08/537,782 patent/US5824652A/en not_active Expired - Fee Related
- 1994-04-21 WO PCT/SI1994/000003 patent/WO1994024152A1/en not_active Ceased

Also Published As

Publication number	Publication date
JPH09506856A (ja)	1997-07-08
US5824652A (en)	1998-10-20
EP0695308B1 (de)	1998-07-01
ES2120039T3 (es)	1998-10-16
SI9300212A (en)	1994-12-31
DE69411380T2 (de)	1999-04-01
EP0695308A1 (de)	1996-02-07
DE69411380D1 (de)	1998-08-06
JP2886987B2 (ja)	1999-04-26
WO1994024152A1 (en)	1994-10-27

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