ATE168269T1 - Antithrombogene und/oder antimikrobielle zusammensetzung - Google Patents

Antithrombogene und/oder antimikrobielle zusammensetzung

Info

Publication number: ATE168269T1
Authority: AT; Austria
Prior art keywords: reacted; quaternary ammonium; ionic surfactants; antithromabic; antimicrobial composition
Prior art date: 1990-07-12

Application number

AT91909862T

Other languages

English (en)

Inventor

Richard James Whitbourne

Margaret Anne Mangan

Original Assignee

Sts Biopolymers Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-07-12

Filing date

1991-05-02

Publication date

1998-08-15

1991-05-02 Application filed by Sts Biopolymers Inc filed Critical Sts Biopolymers Inc

1998-08-15 Application granted granted Critical

1998-08-15 Publication of ATE168269T1 publication Critical patent/ATE168269T1/de

Links

230000000845 anti-microbial effect Effects 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
239000002563 ionic surfactant Substances 0.000 abstract 3
HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 2
239000003242 anti bacterial agent Substances 0.000 abstract 2
229940088710 antibiotic agent Drugs 0.000 abstract 2
229960002897 heparin Drugs 0.000 abstract 2
229920000669 heparin Polymers 0.000 abstract 2
239000008177 pharmaceutical agent Substances 0.000 abstract 2
150000003856 quaternary ammonium compounds Chemical class 0.000 abstract 2
230000002965 anti-thrombogenic effect Effects 0.000 abstract 1
239000004599 antimicrobial Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
229920003176 water-insoluble polymer Polymers 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
- A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Transplantation (AREA)
Materials Engineering (AREA)
Hematology (AREA)
Dermatology (AREA)
Oral & Maxillofacial Surgery (AREA)
Surgery (AREA)
Materials For Medical Uses (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT91909862T 1990-07-12 1991-05-02 Antithrombogene und/oder antimikrobielle zusammensetzung ATE168269T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US55192490A	1990-07-12	1990-07-12
US66245291A	1991-02-28	1991-02-28

Publications (1)

Publication Number	Publication Date
ATE168269T1 true ATE168269T1 (de)	1998-08-15

Family

ID=27069899

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91909862T ATE168269T1 (de)	1990-07-12	1991-05-02	Antithrombogene und/oder antimikrobielle zusammensetzung

Country Status (7)

Country	Link
EP (1)	EP0626854B1 (de)
AT (1)	ATE168269T1 (de)
CA (1)	CA2087102C (de)
DE (1)	DE69129812T2 (de)
DK (1)	DK0626854T3 (de)
ES (1)	ES2120961T3 (de)
WO (1)	WO1992000747A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69331616T2 (de)	1992-09-26	2002-08-01	Aventis Bulk S.P.A., Mailand/Milano	Zentrale Venenkatheter mit aufgebrachtem Lipodalbaheptid-Antibiotikum zur Vermeidung von katheterbezogenen Infektionen
US5886026A (en) *	1993-07-19	1999-03-23	Angiotech Pharmaceuticals Inc.	Anti-angiogenic compositions and methods of use
US5532311A (en) *	1995-02-01	1996-07-02	Minnesota Mining And Manufacturing Company	Process for modifying surfaces
US5583213A (en) *	1995-05-12	1996-12-10	Minnesota Mining And Manufacturing Company	Process to activate sulfated polysaccharides
US6051017A (en)	1996-02-20	2000-04-18	Advanced Bionics Corporation	Implantable microstimulator and systems employing the same
US5916585A (en) *	1996-06-03	1999-06-29	Gore Enterprise Holdings, Inc.	Materials and method for the immobilization of bioactive species onto biodegradable polymers
US6495579B1 (en)	1996-12-02	2002-12-17	Angiotech Pharmaceuticals, Inc.	Method for treating multiple sclerosis
US6515016B2 (en)	1996-12-02	2003-02-04	Angiotech Pharmaceuticals, Inc.	Composition and methods of paclitaxel for treating psoriasis
US6197289B1 (en)	1997-07-01	2001-03-06	Terumo Cardiovascular Systems Corporation	Removal of biologically active agents
US5945457A (en) *	1997-10-01	1999-08-31	A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science	Process for preparing biologically compatible polymers and their use in medical devices
JP3228409B2 (ja) *	1997-12-05	2001-11-12	東洋紡績株式会社	血液適合性組成物および医療用具
US6919372B1 (en) *	1997-12-26	2005-07-19	Yamanouchi Pharmaceutical Co., Ltd.	Sustained release pharmaceutical compositions
US7208011B2 (en)	2001-08-20	2007-04-24	Conor Medsystems, Inc.	Implantable medical device with drug filled holes
US20040254635A1 (en)	1998-03-30	2004-12-16	Shanley John F.	Expandable medical device for delivery of beneficial agent
US6241762B1 (en)	1998-03-30	2001-06-05	Conor Medsystems, Inc.	Expandable medical device with ductile hinges
US7208010B2 (en)	2000-10-16	2007-04-24	Conor Medsystems, Inc.	Expandable medical device for delivery of beneficial agent
WO1999055396A1 (en)	1998-04-27	1999-11-04	Surmodics, Inc.	Bioactive agent release coating
AU6261499A (en)	1998-09-23	2000-04-10	Phycogen, Inc.	Antifouling agents
US6120847A (en) *	1999-01-08	2000-09-19	Scimed Life Systems, Inc.	Surface treatment method for stent coating
US6419692B1 (en)	1999-02-03	2002-07-16	Scimed Life Systems, Inc.	Surface protection method for stents and balloon catheters for drug delivery
US6156373A (en)	1999-05-03	2000-12-05	Scimed Life Systems, Inc.	Medical device coating methods and devices
DE60133053T2 (de)	2000-10-16	2009-02-26	Conor Medsystems, Inc., Menlo Park	Ausdehnbare medizinische Vorrichtung zur Abgabe eines nützlichen Agens
EP1402871B1 (de) *	2001-06-05	2009-02-18	Toyo Boseki Kabushiki Kaisha	Antithrombotische zusammensetzungen und diese enthaltende medizinische instrumente
US7056338B2 (en)	2003-03-28	2006-06-06	Conor Medsystems, Inc.	Therapeutic agent delivery device with controlled therapeutic agent release rates
JP2007532187A (ja)	2004-04-06	2007-11-15	サーモディクス，インコーポレイティド	生物活性物質のためのコーティング組成物
USD516723S1 (en)	2004-07-06	2006-03-07	Conor Medsystems, Inc.	Stent wall structure

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4127647A (en) *	1975-04-08	1978-11-28	Meiji Seika Kaisha, Ltd.	Process for preparation of stable amorphous macrolide antibiotic solids
US4871357A (en) *	1986-01-21	1989-10-03	Baxter International Inc.	Ionic heparin coating
AU2902289A (en) *	1987-12-08	1989-07-05	Mark Chasin	Method of forming bioerodible implants for improved controlled drug release
US5019096A (en) *	1988-02-11	1991-05-28	Trustees Of Columbia University In The City Of New York	Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
US4938763B1 (en) *	1988-10-03	1995-07-04	Atrix Lab Inc	Biodegradable in-situ forming implants and method of producing the same

1991
- 1991-05-02 DE DE69129812T patent/DE69129812T2/de not_active Expired - Fee Related
- 1991-05-02 ES ES91909862T patent/ES2120961T3/es not_active Expired - Lifetime
- 1991-05-02 EP EP91909862A patent/EP0626854B1/de not_active Expired - Lifetime
- 1991-05-02 AT AT91909862T patent/ATE168269T1/de not_active IP Right Cessation
- 1991-05-02 DK DK91909862T patent/DK0626854T3/da active
- 1991-05-02 WO PCT/US1991/002868 patent/WO1992000747A1/en not_active Ceased
- 1991-05-02 CA CA002087102A patent/CA2087102C/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK0626854T3 (da)	1999-04-19
WO1992000747A1 (en)	1992-01-23
EP0626854A4 (de)	1993-09-02
CA2087102A1 (en)	1992-01-13
EP0626854B1 (de)	1998-07-15
DE69129812D1 (de)	1998-08-20
EP0626854A1 (de)	1994-12-07
CA2087102C (en)	2002-04-23
ES2120961T3 (es)	1998-11-16
DE69129812T2 (de)	1999-02-11

Legal Events

Date	Code	Title	Description
1999-02-15	UEP	Publication of translation of european patent specification
2001-02-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE168269T1 (de)	1998-08-15	Antithrombogene und/oder antimikrobielle zusammensetzung
DE69109351D1 (de)	1995-06-08	Antimikrobielle Zusammensetzung.
FI923252A0 (fi)	1992-07-15	Antimikrobiella kompositioner.
NZ222149A (en)	1989-10-27	Disinfectant compositions containing quaternary ammonium compounds and/or substituted guanidine anti-microbial agents
DK0533017T3 (da)	1997-03-24	Vandbaserede, opløsningsmiddel- og emulgatorfrie mikrobicide kombinationer af aktive stoffer
DE69113117D1 (de)	1995-10-26	Schmiermittelzusammensetzungen.
DE69105462D1 (de)	1995-01-12	Desinfizierende Zusammensetzung.
DE69105870D1 (de)	1995-01-26	Kationische Verbindung und Reinigungsmittelzusammensetzung.
TR28023A (tr)	1996-01-02	Yüzeyaktif iyon cifti floresanli beyazlatici terkipleri.
KR950700911A (ko)	1995-02-20	살균약제로서의 치환된 3-피롤리디닐티오-카르바페넴(Substituted 3-Pyrrolidinylthio-Carbapenems as Antimicrobial Agents)
ES2099087T3 (es)	1997-05-16	Composicion anti-trombogena y/o antimicrobiana.
AU642753B2 (en)	1993-10-28	Halogen-containing compounds, herbicidal composition containing the same as an active ingredient, and intermediary compounds therefor
BR9101255A (pt)	1991-11-05	Composto,composicao e processo fungicida,composicao e processo inseticida ou acaricida
ITRM910273A1 (it)	1992-10-22	Composizione insetticida.
IT1243389B (it)	1994-06-10	Derivati poliaminopirrolcarbossiamidici, processi di preparazione e composizioni farmaceutiche che li contengono.
BR9712954A (pt)	1999-12-07	Heterociclos de nitrogênio quaternários, processos para sua preparação e seu emprego como composições praguicidas
DE69103427D1 (de)	1994-09-15	Chemische zusammensetzungen.
ATE106438T1 (de)	1994-06-15	Benzotriazolderivate enthaltende schmiermittelzusammensetzungen.
BR9100315A (pt)	1991-10-22	Composto,composicao lubrificante,metodo de estabilizacao de lubrificantes
YU146490A (sh)	1992-12-21	S-substituirani beta-tioakrilamidi in njihova uporaba kot mikrobicidi
FI913326L (fi)	1992-01-11	Herbicida kompositioner.
AU2721995A (en)	1996-02-08	Coated pesticidal agents, processing for their preparation and compositions containing them
ITRM910387A0 (it)	1991-06-04	Composto di dicloroanilina, composizioni che lo contengono e relativo metodo di preparazione.
DE69006282D1 (de)	1994-03-10	Keimtötende Zusammensetzung.
FI921475A7 (fi)	1992-04-03	1,4-dihydro-4-okso-3-kinoliinijohdannaisia selektiivisesti toksisina n isäkkään antibakteerisina aineina