ATE169227T1 - Hemmung von gefässverengung unter verwendung von anti-padgem antikörpern. - Google Patents

Hemmung von gefässverengung unter verwendung von anti-padgem antikörpern.

Info

Publication number
ATE169227T1
ATE169227T1 AT92922039T AT92922039T ATE169227T1 AT E169227 T1 ATE169227 T1 AT E169227T1 AT 92922039 T AT92922039 T AT 92922039T AT 92922039 T AT92922039 T AT 92922039T AT E169227 T1 ATE169227 T1 AT E169227T1
Authority
AT
Austria
Prior art keywords
padgem
vaso
contraction
inhibition
intravascular
Prior art date
Application number
AT92922039T
Other languages
English (en)
Inventor
Theresa M Palabrica
Bruce E Furie
Barbara C Furie
Roy R Lobb
Christopher D Benjamin
Original Assignee
Biogen Inc
New England Medical Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc, New England Medical Center Inc filed Critical Biogen Inc
Application granted granted Critical
Publication of ATE169227T1 publication Critical patent/ATE169227T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AT92922039T 1991-09-30 1992-09-30 Hemmung von gefässverengung unter verwendung von anti-padgem antikörpern. ATE169227T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76883491A 1991-09-30 1991-09-30

Publications (1)

Publication Number Publication Date
ATE169227T1 true ATE169227T1 (de) 1998-08-15

Family

ID=25083621

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92922039T ATE169227T1 (de) 1991-09-30 1992-09-30 Hemmung von gefässverengung unter verwendung von anti-padgem antikörpern.

Country Status (9)

Country Link
EP (1) EP0606391B1 (de)
JP (1) JPH07502726A (de)
AT (1) ATE169227T1 (de)
AU (1) AU678757B2 (de)
CA (1) CA2120240A1 (de)
DE (1) DE69226531T2 (de)
DK (1) DK0606391T3 (de)
ES (1) ES2123010T3 (de)
WO (1) WO1993006863A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770198A (en) * 1988-05-18 1998-06-23 The Research Foundation Of The State Of New York Platelet-specific chimeric 7E3 immunoglobulin
AU2305201A (en) * 1993-11-05 2001-05-03 Centocor Inc. Platelet-specific chimeric immunoglobulin and methods of use therefor
CN1140295C (zh) * 1993-11-05 2004-03-03 森特克公司 血小板特异性的嵌合性免疫球蛋白及其使用方法
EP1714661A3 (de) * 2000-05-19 2012-03-14 The Center for Blood Research, INC. Verfahren zur Diagnose und Behandlung von hämostatischen Störungen durch Modulation der P-Selectin Aktivität
AU6173501A (en) 2000-05-19 2001-12-03 Blood Res Center Methods for diagnosing and treating hemostatic disorders by modulating p-selectin activity
CN1942483B (zh) 2004-04-13 2012-09-26 弗·哈夫曼-拉罗切有限公司 抗p型选凝素抗体
US8945565B2 (en) 2006-12-01 2015-02-03 Selexys Pharmaceuticals Corporation Methods of treating inflammatory or thrombotic conditions with anti-P-selectin antibodies
US20110212096A1 (en) 2006-12-01 2011-09-01 Scott Rollins Anti-p-selectin antibodies and methods of their use and identification
SI2662091T1 (sl) 2006-12-01 2019-01-31 Novartis Ag Protitelesa proti P-selektinu in postopki za njihovo uporabo za zdravljenje vnetnih bolezni
KR20140019035A (ko) 2008-09-19 2014-02-13 에프. 호프만-라 로슈 아게 신규한 항체 제형
EP3595645A1 (de) 2017-03-15 2020-01-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Pharmazeutische zusammensetzungen zur behandlung von thrombosen bei patienten mit einem myeloproliferativem neoplasma
EP3642631B1 (de) 2017-06-20 2022-03-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Verfahren zur erkennung, ob patienten mit akuter dekompensierter herzinsuffizienz (adhf) einen hyperkoagulierbaren zustand aufweisen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991001380A1 (fr) * 1989-07-25 1991-02-07 Institut National De La Sante Et De La Recherche Medicale Anticorps monoclonaux diriges contre des proteines impliquees dans les fonctions plaquettaires, leur application en tant qu'agent diagnostique et therapeutique
JPH05504470A (ja) * 1989-10-20 1993-07-15 ニューイングランド・メディカル・センター・ホスピタルズ・インコーポレーテッド Ｐａｄｇｅｍを介した細胞結合の阻害
WO1991007993A1 (en) * 1989-11-30 1991-06-13 Mathew Vadas Anti-inflammatory and anti-adhesive factors

Also Published As

Publication number Publication date
EP0606391A1 (de) 1994-07-20
DE69226531T2 (de) 1999-05-06
DK0606391T3 (da) 1999-05-03
AU2869492A (en) 1993-05-03
AU678757B2 (en) 1997-06-12
WO1993006863A1 (en) 1993-04-15
DE69226531D1 (de) 1998-09-10
CA2120240A1 (en) 1993-03-31
EP0606391B1 (de) 1998-08-05
ES2123010T3 (es) 1999-01-01
JPH07502726A (ja) 1995-03-23

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee