ATE169228T1 - Verbesserung der durchdringungfähigkeit von topischen anwendbaren formulierungen - Google Patents
Verbesserung der durchdringungfähigkeit von topischen anwendbaren formulierungenInfo
- Publication number
- ATE169228T1 ATE169228T1 AT92309727T AT92309727T ATE169228T1 AT E169228 T1 ATE169228 T1 AT E169228T1 AT 92309727 T AT92309727 T AT 92309727T AT 92309727 T AT92309727 T AT 92309727T AT E169228 T1 ATE169228 T1 AT E169228T1
- Authority
- AT
- Austria
- Prior art keywords
- penetractability
- improving
- topically applicable
- vitamin
- penetration
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 4
- 229930003427 Vitamin E Natural products 0.000 abstract 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract 2
- 229940046009 vitamin E Drugs 0.000 abstract 2
- 235000019165 vitamin E Nutrition 0.000 abstract 2
- 239000011709 vitamin E Substances 0.000 abstract 2
- 239000008406 cosmetic ingredient Substances 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- -1 etc. ) Substances 0.000 abstract 1
- 239000010408 film Substances 0.000 abstract 1
- 239000000499 gel Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000006210 lotion Substances 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 239000006072 paste Substances 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78542691A | 1991-10-23 | 1991-10-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE169228T1 true ATE169228T1 (de) | 1998-08-15 |
Family
ID=25135484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92309727T ATE169228T1 (de) | 1991-10-23 | 1992-10-23 | Verbesserung der durchdringungfähigkeit von topischen anwendbaren formulierungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6017520A (de) |
| EP (1) | EP0539215B1 (de) |
| JP (1) | JP2671248B2 (de) |
| KR (1) | KR930007445A (de) |
| AT (1) | ATE169228T1 (de) |
| AU (1) | AU658681B2 (de) |
| CA (1) | CA2081269C (de) |
| DE (1) | DE69226491T2 (de) |
| DK (1) | DK0539215T3 (de) |
| ES (1) | ES2119800T3 (de) |
| NZ (1) | NZ244862A (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0695177T3 (da) * | 1993-04-20 | 1998-09-28 | Hexal Ag | Plaster indeholdende aktivt stof |
| CN1129400A (zh) * | 1994-05-06 | 1996-08-21 | 阿尔康实验室公司 | 维生素e生育酚衍生物在眼科组合物中的应用 |
| GB9409778D0 (en) | 1994-05-16 | 1994-07-06 | Dumex Ltd As | Compositions |
| AU4472396A (en) * | 1994-12-30 | 1996-07-24 | American Home Products Corporation | Clear non-alcoholic hydrocortisone solutions |
| EP1374861A1 (de) | 1995-04-21 | 2004-01-02 | Sekisui Kagaku Kogyo Kabushiki Kaisha | Präparate zur äusserlichen Anwendung zur Behandlung von Dermatosen |
| AU713278B2 (en) * | 1996-03-14 | 1999-11-25 | Johnson & Johnson Consumer Companies, Inc. | Cleansing and moisturizing surfactant compositions |
| US6730679B1 (en) | 1996-03-22 | 2004-05-04 | Smithkline Beecham Corporation | Pharmaceutical formulations |
| IT1282778B1 (it) * | 1996-05-31 | 1998-03-31 | Giorgio Panin | Vitamina "e" acetato quale prodotto per applicazione topica |
| DE19646392A1 (de) * | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
| AUPO379596A0 (en) | 1996-11-22 | 1996-12-19 | Soltec Research Pty Ltd | Percutaneous delivery system |
| US20040067212A1 (en) * | 1998-03-11 | 2004-04-08 | Kabushiki Kaisha Soken | Skin conditioner |
| KR20000000840A (ko) * | 1998-06-03 | 2000-01-15 | 김영대 | 신규한 폴리옥시프로필렌폴리옥시에틸렌 비타민 e 및 그의제조방법 |
| FR2761600B1 (fr) | 1998-06-19 | 2000-03-31 | Oreal | Composition moussante pour le lavage et le traitement des cheveux et/ou du cuir chevelu a base d'un principe actif, d'un tensioactif anionique, d'un tensioactif amphotere et d'un agent propenetrant |
| US6825234B2 (en) | 1998-12-10 | 2004-11-30 | Nexmed (Holdings) , Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
| US6486207B2 (en) | 1998-12-10 | 2002-11-26 | Nexmed (Holdings), Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
| US20070191320A1 (en) * | 1998-12-10 | 2007-08-16 | Nexmed Holdings, Inc. | Methods of treatment for female sexual arousal disorder |
| CA2360216A1 (en) * | 1999-02-12 | 2000-08-17 | David Andrew Jakubovic | Cosmetic compositions containing vitamin b3 compounds |
| US6787342B2 (en) * | 2000-02-16 | 2004-09-07 | Merial Limited | Paste formulations |
| US6383505B1 (en) | 2000-11-09 | 2002-05-07 | Steris Inc | Fast-acting antimicrobial lotion with enhanced efficacy |
| US6429231B1 (en) * | 2001-09-24 | 2002-08-06 | Bradley Pharmaceuticals, Inc. | Compositions containing antimicrobials and urea for the treatment of dermatological disorders and methods for their use |
| AU2003234452A1 (en) * | 2002-05-06 | 2003-11-11 | Elan Pharma International Ltd. | Nanoparticulate nystatin formulations |
| CA2487882A1 (en) * | 2002-05-31 | 2003-12-11 | University Of Mississippi | Transmucosal delivery of cannabinoids |
| DE10224612A1 (de) * | 2002-06-04 | 2003-12-24 | Lohmann Therapie Syst Lts | Wirkstoffhaltige filmförmige Zubereitungen mit verbesserter chemischer Stabilität, und Verfahren zu deren Herstellung |
| JP2004123633A (ja) * | 2002-10-03 | 2004-04-22 | Medorekkusu:Kk | 外用製剤 |
| US7374772B2 (en) * | 2002-11-07 | 2008-05-20 | Bommarito Alexander A | Topical antifungal treatment |
| US20040191279A1 (en) * | 2003-03-28 | 2004-09-30 | Klofta Thomas James | Tacky skin care compositions and articles having tacky skin care compositions disposed thereon |
| MXPA06003668A (es) * | 2003-10-03 | 2006-06-05 | Procter & Gamble | Composicion topica. |
| US9308268B2 (en) * | 2005-02-14 | 2016-04-12 | Transdermal Corp | Solubilized benzoyl peroxyde acne |
| US9314431B2 (en) * | 2005-02-14 | 2016-04-19 | Transdermal Corp | Solubilized benzoyl small molecule |
| US20090304820A1 (en) * | 2008-06-05 | 2009-12-10 | Pankaj Modi | Solubilized benzoyl peroxide topical drug formulation for the treatment of acne |
| US7563464B1 (en) * | 2005-04-22 | 2009-07-21 | Bruce Eric Hudkins | Treatment of mucosal membranes utilizing phytoestrogen |
| WO2008037809A1 (en) * | 2006-09-29 | 2008-04-03 | Abbott Gmbh & Co. Kg | Transmucosal administration of fibrate compounds and delivery system therefor |
| CA2719512A1 (en) | 2010-11-01 | 2012-05-01 | Stiefel Research Australia Pty Ltd | Polymeric topical compositions |
| WO2018122344A1 (en) | 2016-12-29 | 2018-07-05 | Nestlé Skin Health Sa | Composition comprising a crosslinked hyaluronic acid (ha) in combination with a low-molecular ha and/or an agent stimulating endogenous ha synthesis |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4177267A (en) * | 1963-12-09 | 1979-12-04 | Crown Zellerbach | Enhancing tissue penetration of physiologically active steroidal agents with DMSC |
| IN142640B (de) * | 1975-01-17 | 1977-08-06 | Johnson & Johnson | |
| JPS5579318A (en) * | 1978-12-07 | 1980-06-14 | Taisho Pharmaceut Co Ltd | Poultice |
| JPS5610887A (en) * | 1979-07-09 | 1981-02-03 | Babcock Hitachi Kk | Handrall structure of joint portion of duct |
| JPS5855417A (ja) * | 1981-09-27 | 1983-04-01 | Nitto Electric Ind Co Ltd | 医薬組成物 |
| DE3579343D1 (de) * | 1984-03-07 | 1990-10-04 | Roshdy Ismail | Mittel zur behandlung und zum schutz der haut. |
| JPS60224638A (ja) * | 1984-04-23 | 1985-11-09 | Kao Corp | 経皮吸収促進剤およびこれを含有する外用剤 |
| US4824676A (en) * | 1984-10-11 | 1989-04-25 | Schering Corporation | Physiological means of enhancing transdermal delivery of drugs |
| US4886783A (en) * | 1986-01-31 | 1989-12-12 | Nelson Research & Development Co. | Penetration enhancers for transdermal delivery of systemic agents |
| US4917896A (en) * | 1986-08-15 | 1990-04-17 | Nelson Research & Development Co. | Penetration enhancers for transdermal delivery of systemic agents |
| US4808414A (en) * | 1986-09-29 | 1989-02-28 | Nelson Research & Development Co. | Amide penetration enhancers for transdermal delivery of systemic agents |
| GB8630721D0 (en) * | 1986-12-23 | 1987-02-04 | Unilever Plc | Cosmetic compositions |
| US4847069A (en) * | 1987-10-22 | 1989-07-11 | The Procter & Gamble Company | Photoprotection compositions comprising sorbohydroxamic acid and an anti-inflammatory agent |
| US4869897A (en) * | 1987-10-22 | 1989-09-26 | The Procter & Gamble Company | Photoprotection compositions comprising sorbohydroxamic acid |
| JP2663136B2 (ja) * | 1988-05-02 | 1997-10-15 | 有限会社野々川商事 | 美白化粧料 |
| ES2062093T3 (es) * | 1988-08-02 | 1994-12-16 | Ciba Geigy Ag | Emplasto de varias capas. |
| AU664178B2 (en) * | 1991-03-19 | 1995-11-09 | Vithal J. Rajadhyaksha | Compositions and method comprising aminoalcohol derivatives as membrane penetration enhancers |
| US5215759A (en) * | 1991-10-01 | 1993-06-01 | Chanel, Inc. | Cosmetic composition |
-
1992
- 1992-10-22 KR KR1019920019450A patent/KR930007445A/ko not_active Abandoned
- 1992-10-22 NZ NZ244862A patent/NZ244862A/en not_active IP Right Cessation
- 1992-10-22 JP JP4307998A patent/JP2671248B2/ja not_active Expired - Lifetime
- 1992-10-22 AU AU27266/92A patent/AU658681B2/en not_active Expired
- 1992-10-23 DE DE69226491T patent/DE69226491T2/de not_active Revoked
- 1992-10-23 AT AT92309727T patent/ATE169228T1/de not_active IP Right Cessation
- 1992-10-23 DK DK92309727T patent/DK0539215T3/da active
- 1992-10-23 ES ES92309727T patent/ES2119800T3/es not_active Expired - Lifetime
- 1992-10-23 EP EP92309727A patent/EP0539215B1/de not_active Revoked
- 1992-10-23 CA CA002081269A patent/CA2081269C/en not_active Expired - Lifetime
-
1997
- 1997-05-02 US US08/850,377 patent/US6017520A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2081269C (en) | 2002-03-05 |
| AU2726692A (en) | 1993-04-29 |
| KR930007445A (ko) | 1993-05-20 |
| DE69226491D1 (de) | 1998-09-10 |
| CA2081269A1 (en) | 1993-04-24 |
| EP0539215B1 (de) | 1998-08-05 |
| JPH06128176A (ja) | 1994-05-10 |
| JP2671248B2 (ja) | 1997-10-29 |
| NZ244862A (en) | 1995-07-26 |
| DK0539215T3 (da) | 1999-05-03 |
| AU658681B2 (en) | 1995-04-27 |
| EP0539215A1 (de) | 1993-04-28 |
| DE69226491T2 (de) | 1999-01-14 |
| US6017520A (en) | 2000-01-25 |
| ES2119800T3 (es) | 1998-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| RZN | Patent revoked |