ATE170075T1 - Antivirales arzneimittel enthaltend prostratin - Google Patents

Antivirales arzneimittel enthaltend prostratin

Info

Publication number: ATE170075T1
Authority: AT; Austria
Prior art keywords: antiviral; prostratin; present; product containing; medicinal product
Prior art date: 1990-05-30

Application number

AT91910575T

Other languages

English (en)

Inventor

Michael R Boyd

Paul A Cox

Gordon M Cragg

Peter M Blumberg

Nancy A Sharkey

Junichi Ishitoya

James B Mcmahon

John A Beutler

Owen S Weislow

John H Ii Cardellina

Kirk R Gustafson

Original Assignee

Us Health

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-05-30

Filing date

1991-05-24

Publication date

1998-09-15

1991-05-24 Application filed by Us Health filed Critical Us Health

1998-09-15 Application granted granted Critical

1998-09-15 Publication of ATE170075T1 publication Critical patent/ATE170075T1/de

Links

230000000840 anti-viral effect Effects 0.000 title abstract 5
NUQJULCGNZMBEF-UHFFFAOYSA-N Prostratin Natural products COC(=O)C12CC(C)C3(O)C(C=C(CO)CC4(O)C3C=C(C)C4=O)C1C2(C)C NUQJULCGNZMBEF-UHFFFAOYSA-N 0.000 title abstract 2
BOJKFRKNLSCGHY-HXGSDTCMSA-N prostratin Chemical compound C1=C(CO)C[C@]2(O)C(=O)C(C)=C[C@H]2[C@@]2(O)[C@H](C)C[C@@]3(OC(C)=O)C(C)(C)[C@H]3[C@@H]21 BOJKFRKNLSCGHY-HXGSDTCMSA-N 0.000 title abstract 2
229940126601 medicinal product Drugs 0.000 title 1
208000036142 Viral infection Diseases 0.000 abstract 1
230000002411 adverse Effects 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
PHEDXBVPIONUQT-RGYGYFBISA-N phorbol 13-acetate 12-myristate Chemical class C([C@]1(O)C(=O)C(C)=C[C@H]1[C@@]1(O)[C@H](C)[C@H]2OC(=O)CCCCCCCCCCCCC)C(CO)=C[C@H]1[C@H]1[C@]2(OC(C)=O)C1(C)C PHEDXBVPIONUQT-RGYGYFBISA-N 0.000 abstract 1
230000000722 protumoral effect Effects 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1
230000002110 toxicologic effect Effects 0.000 abstract 1
231100000723 toxicological property Toxicity 0.000 abstract 1
230000009385 viral infection Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines Containing Plant Substances (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT91910575T 1990-05-30 1991-05-24 Antivirales arzneimittel enthaltend prostratin ATE170075T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US53056290A	1990-05-30	1990-05-30

Publications (1)

Publication Number	Publication Date
ATE170075T1 true ATE170075T1 (de)	1998-09-15

Family

ID=24114097

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91910575T ATE170075T1 (de)	1990-05-30	1991-05-24	Antivirales arzneimittel enthaltend prostratin

Country Status (10)

Country	Link
US (1)	US5599839A (de)
EP (1)	EP0531413B1 (de)
JP (1)	JPH0737380B2 (de)
AT (1)	ATE170075T1 (de)
AU (1)	AU639343B2 (de)
CA (1)	CA2083945C (de)
DE (1)	DE69130063T2 (de)
DK (1)	DK0531413T3 (de)
ES (1)	ES2120962T3 (de)
WO (1)	WO1991018595A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1924548B1 (de)	2005-07-13	2018-03-28	Salvia Sciences, Inc.	Ester-prodrugs von prostratin und verwandten phorbolverbindungen
US9974764B2 (en)	2007-01-31	2018-05-22	Biosuccess Biotech Co. Ltd.	Compositions and methods of use of phorbol esters in the treatment of neoplasms
US11696908B2 (en)	2007-01-31	2023-07-11	Biosuccess Biotech Co. Ltd.	Compositions and methods of use of phorbol esters
US11564901B2 (en)	2007-01-31	2023-01-31	Biosuccess Biotech Co., Ltd.	Compositions and methods of use of phorbol esters
EP2170053A4 (de)	2007-01-31	2010-06-23	Biosuccess Biotech Company	Zusammensetzungen und verfahren für die verwendung von phorbolestern
US9533938B2 (en)	2007-01-31	2017-01-03	Biosuccess Biotech Co., Ltd.	Compositions and methods of use of phorbol esters for the treatment of stroke
US10369222B2 (en)	2012-01-18	2019-08-06	Biosuccess Biotech Co., Ltd.	Compositions and methods of use of phorbol esters for the treatment of stroke
US9636317B2 (en)	2007-01-31	2017-05-02	Biosuccess Biotech Co. Ltd.	Compositions and methods of use of phorbol esters
US8067632B2 (en)	2007-07-26	2011-11-29	The Board Of Trustees Of The Leland Stanford Junior University	Process to produce prostratin and structural or functional analogs thereof
US20110224297A1 (en) *	2008-04-11	2011-09-15	Brown Stephen J	Methods of administering prostratin and structural analogs thereof
US20100298171A1 (en) *	2009-05-22	2010-11-25	Affymetrix, Inc.	Apparatus for polymer synthesis
WO2011014561A1 (en) *	2009-07-29	2011-02-03	He Johnny J	Extracts of medicinal plant and uses thereof
US10099996B2 (en)	2012-01-18	2018-10-16	Biosuccess Biotech Co. Ltd.	Compositions and methods of use of phorbol esters in the treatment of neoplasms
US9550722B2 (en)	2012-01-18	2017-01-24	Biosuccess Biotech Co. Ltd.	Compositions and methods of use of phorbal esters for the treatment of stroke
ITUB20153575A1 (it) *	2015-09-11	2017-03-11	Fca Italy Spa	"Sospensione per una ruota sterzante di autoveicolo, con asse di sterzo semi-virtuale"

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4902716A (en) *	1984-12-18	1990-02-20	Harbor Branch Oceanographic Institutuion, Inc.	Anti-viral chamigrene derivatives

1991
- 1991-05-24 AT AT91910575T patent/ATE170075T1/de not_active IP Right Cessation
- 1991-05-24 DE DE69130063T patent/DE69130063T2/de not_active Expired - Lifetime
- 1991-05-24 JP JP3510273A patent/JPH0737380B2/ja not_active Expired - Lifetime
- 1991-05-24 WO PCT/US1991/003619 patent/WO1991018595A1/en not_active Ceased
- 1991-05-24 AU AU79099/91A patent/AU639343B2/en not_active Expired
- 1991-05-24 DK DK91910575T patent/DK0531413T3/da active
- 1991-05-24 CA CA002083945A patent/CA2083945C/en not_active Expired - Lifetime
- 1991-05-24 EP EP91910575A patent/EP0531413B1/de not_active Expired - Lifetime
- 1991-05-24 ES ES91910575T patent/ES2120962T3/es not_active Expired - Lifetime
1995
- 1995-04-17 US US08/424,558 patent/US5599839A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH0737380B2 (ja)	1995-04-26
EP0531413A4 (en)	1993-06-16
US5599839A (en)	1997-02-04
EP0531413A1 (de)	1993-03-17
AU7909991A (en)	1991-12-31
EP0531413B1 (de)	1998-08-26
CA2083945C (en)	1995-02-07
DK0531413T3 (da)	1999-05-25
DE69130063D1 (de)	1998-10-01
DE69130063T2 (de)	1999-02-25
ES2120962T3 (es)	1998-11-16
JPH05506451A (ja)	1993-09-22
AU639343B2 (en)	1993-07-22
WO1991018595A1 (en)	1991-12-12

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Legal Events

Date	Code	Title	Description
2011-08-15	EELA	Cancelled due to lapse of time