ATE171939T1 - Phenoxyphenylcyclopentenyl-hydroxyharnstoffe - Google Patents

Phenoxyphenylcyclopentenyl-hydroxyharnstoffe

Info

Publication number
ATE171939T1
ATE171939T1 AT94922374T AT94922374T ATE171939T1 AT E171939 T1 ATE171939 T1 AT E171939T1 AT 94922374 T AT94922374 T AT 94922374T AT 94922374 T AT94922374 T AT 94922374T AT E171939 T1 ATE171939 T1 AT E171939T1
Authority
AT
Austria
Prior art keywords
pct
date
above compounds
sec
hydrogen
Prior art date
Application number
AT94922374T
Other languages
English (en)
Inventor
Akiyoshi Kawai
Rodney W Stevens
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE171939T1 publication Critical patent/ATE171939T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT94922374T 1993-08-19 1994-08-15 Phenoxyphenylcyclopentenyl-hydroxyharnstoffe ATE171939T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20545393 1993-08-19

Publications (1)

Publication Number Publication Date
ATE171939T1 true ATE171939T1 (de) 1998-10-15

Family

ID=16507136

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94922374T ATE171939T1 (de) 1993-08-19 1994-08-15 Phenoxyphenylcyclopentenyl-hydroxyharnstoffe

Country Status (27)

Country Link
US (1) US5792882A (de)
EP (1) EP0720598B1 (de)
JP (1) JP2794343B2 (de)
KR (1) KR0170623B1 (de)
CN (1) CN1077568C (de)
AT (1) ATE171939T1 (de)
AU (1) AU674776B2 (de)
BR (1) BR9407314A (de)
CA (1) CA2169066C (de)
CO (1) CO4230229A1 (de)
CZ (1) CZ288358B6 (de)
DE (1) DE69413831T2 (de)
DK (1) DK0720598T3 (de)
EC (1) ECSP941144A (de)
EG (1) EG20530A (de)
ES (1) ES2121218T3 (de)
FI (1) FI114466B (de)
IL (1) IL110628A (de)
MY (1) MY111140A (de)
NO (1) NO305595B1 (de)
NZ (1) NZ269849A (de)
PE (1) PE57194A1 (de)
PL (1) PL176223B1 (de)
RU (1) RU2125987C1 (de)
TW (2) TW448144B (de)
WO (1) WO1995005360A1 (de)
ZA (1) ZA946253B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1151125C (zh) * 1994-06-27 2004-05-26 千年药品公司 治疗心血管疾病,炎症和免疫疾病的化合物和方法
CA2205033C (en) * 1994-11-10 2001-12-11 Akiyoshi Kawai Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas as 5-lipoxygenase inhibitors
WO1996016054A1 (en) * 1994-11-18 1996-05-30 Pfizer Pharmaceuticals Inc. Cycloalkenyl-n-hydroxyureas
EP1745774A3 (de) 1997-08-11 2007-04-11 Pfizer Products Inc. Feste pharmazeutische Dispersionen mit erhöhter Bioverfügbarkeit
US6121323A (en) * 1997-12-03 2000-09-19 3M Innovative Properties Company Bishydroxyureas
ATE495148T1 (de) 2004-12-02 2011-01-15 Amorepacific Corp Die produktion von tnf-alpha inhibierenden 2- cyclopenten-1-onoximderivate
WO2009072807A2 (en) * 2007-12-03 2009-06-11 Amorepacific Corporation Pharmaceutical composition for preventing or treating fat metabolism-related diseases containing 2-cyclopentene-1-one oxime derivatives
CA2738573C (en) 2009-04-03 2013-02-19 F. Hoffmann-La Roche Ag Compositions of propane-1 sulfonic acid {3-[5-(4-chloro-phenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide and uses thereof
US8512464B2 (en) * 2009-12-02 2013-08-20 3M Innovative Properties Company Functionalized zirconia nanoparticles and high index films made therefrom

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ222168A (en) * 1986-10-20 1991-05-28 Oncogene Science Inc Tumour growth inhibiting protein related to tgf-#b#1 and tgf-#b#2, preparation by genetic engineering methods, antibodies and pharmaceutical compositions
US5026729A (en) * 1987-02-10 1991-06-25 Abbott Laboratories Lipoxygenase inhibiting compounds
AU624896B2 (en) * 1989-02-03 1992-06-25 Wellcome Foundation Limited, The Anti-inflammatory aryl derivatives
US5037853A (en) * 1989-12-28 1991-08-06 Abbott Laboratories Cyclopropyl derivative lipoxygenase inhibitors
US5120752A (en) * 1989-12-28 1992-06-09 Abbott Laboratories Cyclopropyl derivative lipoxygenase inhibitors
GB9025514D0 (en) * 1990-11-23 1991-01-09 Wellcome Found Anti-inflammatory compounds
JP3007138B2 (ja) * 1990-11-27 2000-02-07 ファイザー製薬株式会社 新規なヒドロキサム酸とｎ―ヒドロキシ尿素誘導体およびそれらの組成物
JPH06256285A (ja) * 1990-12-11 1994-09-13 Pfizer Pharmaceut Co Ltd ヒドロキサム酸誘導体およびその用途
US5130485A (en) * 1991-04-23 1992-07-14 Eli Lilly And Company N-hydroxy-N-(3-(2-substituted phenyl)prop-2-enyl)ureas and thioureas useful as 5-lipoxygenase inhibiting agents
US5149097A (en) * 1991-05-01 1992-09-22 Tonello John H Crossword puzzle aid
JPH05163229A (ja) * 1991-12-13 1993-06-29 Pfizer Pharmaceut Co Ltd 新規なシクロプロピル誘導体
JPH05294921A (ja) * 1992-04-17 1993-11-09 Pfizer Pharmaceut Co Ltd 新規なフェニル置換シクロアルキル尿素誘導体および組成物

Also Published As

Publication number Publication date
MY111140A (en) 1999-08-30
ECSP941144A (es) 1995-02-27
BR9407314A (pt) 1996-04-16
FI943799A0 (fi) 1994-08-18
PL176223B1 (pl) 1999-05-31
TW448144B (en) 2001-08-01
CZ48396A3 (en) 1996-07-17
CA2169066C (en) 1999-06-22
EG20530A (en) 1999-07-31
AU7350994A (en) 1995-03-14
FI114466B (fi) 2004-10-29
TW418089B (en) 2001-01-11
JPH08511031A (ja) 1996-11-19
KR0170623B1 (ko) 1999-03-30
CN1129440A (zh) 1996-08-21
NO960631L (no) 1996-02-16
IL110628A0 (en) 1994-11-11
ES2121218T3 (es) 1998-11-16
AU674776B2 (en) 1997-01-09
RU2125987C1 (ru) 1999-02-10
EP0720598B1 (de) 1998-10-07
DK0720598T3 (da) 1999-06-21
NO960631D0 (no) 1996-02-16
EP0720598A1 (de) 1996-07-10
CO4230229A1 (es) 1995-10-19
JP2794343B2 (ja) 1998-09-03
KR960703845A (ko) 1996-08-31
FI943799L (fi) 1995-02-20
NO305595B1 (no) 1999-06-28
DE69413831T2 (de) 1999-02-25
CN1077568C (zh) 2002-01-09
ZA946253B (en) 1996-02-19
US5792882A (en) 1998-08-11
WO1995005360A1 (en) 1995-02-23
PL313037A1 (en) 1996-05-27
DE69413831D1 (de) 1998-11-12
CZ288358B6 (en) 2001-05-16
IL110628A (en) 1998-12-27
CA2169066A1 (en) 1995-02-23
NZ269849A (en) 1997-10-24
PE57194A1 (es) 1995-02-07

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee