ATE172446T1 - Verfahren zur herstellung von radiomarkierten meta-halobenzylguanidin - Google Patents

Verfahren zur herstellung von radiomarkierten meta-halobenzylguanidin

Info

Publication number
ATE172446T1
ATE172446T1 AT95304963T AT95304963T ATE172446T1 AT E172446 T1 ATE172446 T1 AT E172446T1 AT 95304963 T AT95304963 T AT 95304963T AT 95304963 T AT95304963 T AT 95304963T AT E172446 T1 ATE172446 T1 AT E172446T1
Authority
AT
Austria
Prior art keywords
meta
radiom
halobensylguanidine
producing
labeled
Prior art date
Application number
AT95304963T
Other languages
English (en)
Inventor
Duncan H Hunter
Alok Goel
Richard J Flanagan
Original Assignee
Merck Frosst Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada Inc filed Critical Merck Frosst Canada Inc
Application granted granted Critical
Publication of ATE172446T1 publication Critical patent/ATE172446T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001—Acyclic or carbocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT95304963T 1994-07-20 1995-07-17 Verfahren zur herstellung von radiomarkierten meta-halobenzylguanidin ATE172446T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/277,809 US5565185A (en) 1994-07-20 1994-07-20 Process for the preparation of radiolabeled meta-halobenzylguanidine

Publications (1)

Publication Number Publication Date
ATE172446T1 true ATE172446T1 (de) 1998-11-15

Family

ID=23062444

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95304963T ATE172446T1 (de) 1994-07-20 1995-07-17 Verfahren zur herstellung von radiomarkierten meta-halobenzylguanidin

Country Status (5)

Country Link
US (1) US5565185A (de)
EP (1) EP0693467B1 (de)
AT (1) ATE172446T1 (de)
CA (1) CA2153851C (de)
DE (1) DE69505465T2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2345710C (en) * 1997-10-02 2008-12-30 The University Of Western Ontario Preparation of radiolabelled haloaromatics via polymer-bound intermediates
US6461585B1 (en) * 1998-10-02 2002-10-08 The University Of Western Ontario Preparation of radiolabelled haloaromatics via polymer-bound intermediates
US7273601B2 (en) * 2000-07-18 2007-09-25 The University Of Western Ontario Preparation of radiolabelled haloaromatics via polymer-bound intermediates
WO2002070020A2 (en) 2001-03-02 2002-09-12 University Of Western Ontario Polymer precursors of radiolabeled compounds, and methods of making and using the same
JP5265869B2 (ja) 2003-05-02 2013-08-14 ザ ユニバーシティー オブ ウェスタン オンタリオ 放射性医薬化合物の合成に有用な補欠分子族
EP2110367A1 (de) 2008-04-14 2009-10-21 Bayer Schering Pharma Aktiengesellschaft Reinigungsstrategie für direkte nukleophile Verfahren
CA2767470A1 (en) 2009-07-11 2011-01-20 Bayer Pharma Aktiengesellschaft Non-polar and polar leaving groups
WO2011060268A2 (en) * 2009-11-13 2011-05-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Diagnosis and treatment of cancer using histone deacetylase inhibitors and radiolabeled metaiodobenzylguanidine
CN104761421B (zh) * 2014-01-06 2018-01-16 江苏省原子医学研究所 一种无载体[*x]mxbg的制备方法
AU2015335599B2 (en) * 2014-10-24 2020-03-19 Molecular Insight Pharmaceuticals, Inc. Preparations of meta-iodobenzylguanidine and precursors thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4584187A (en) * 1981-04-01 1986-04-22 Wieland Donald M Imaging agent and method of use
US5128118A (en) * 1990-08-09 1992-07-07 Research Triangle Institute Cocaine receptor binding ligands

Also Published As

Publication number Publication date
DE69505465T2 (de) 1999-06-02
DE69505465D1 (de) 1998-11-26
CA2153851C (en) 2006-08-29
CA2153851A1 (en) 1996-01-21
EP0693467B1 (de) 1998-10-21
US5565185A (en) 1996-10-15
EP0693467A1 (de) 1996-01-24

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Legal Events

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