ATE172721T1 - Aminosäurederivate und ihre verwendung als enkephalinase-inhibitoren - Google Patents

Aminosäurederivate und ihre verwendung als enkephalinase-inhibitoren

Info

Publication number
ATE172721T1
ATE172721T1 AT94401632T AT94401632T ATE172721T1 AT E172721 T1 ATE172721 T1 AT E172721T1 AT 94401632 T AT94401632 T AT 94401632T AT 94401632 T AT94401632 T AT 94401632T AT E172721 T1 ATE172721 T1 AT E172721T1
Authority
AT
Austria
Prior art keywords
amino acid
acid derivatives
enkephalinase inhibitors
enkephalinase
image
Prior art date
Application number
AT94401632T
Other languages
English (en)
Inventor
Denis Danvy
Thierry Monteil
Christophe Lusson
Jean-Charles Schwartz
Claude Gros
Nadine Noel
Jeanne-Marie Lecomte
Pierre Duhamel
Lucette Duhamel
Original Assignee
Bioprojet Soc Civ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioprojet Soc Civ filed Critical Bioprojet Soc Civ
Application granted granted Critical
Publication of ATE172721T1 publication Critical patent/ATE172721T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/20Esters of monothiocarboxylic acids
    • C07C327/32Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT94401632T 1993-07-16 1994-07-13 Aminosäurederivate und ihre verwendung als enkephalinase-inhibitoren ATE172721T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9308765A FR2707638B1 (fr) 1993-07-16 1993-07-16 Nouveaux dérivés d'amino-acides, leurs procédés de préparation et leur application thérapeutique.

Publications (1)

Publication Number Publication Date
ATE172721T1 true ATE172721T1 (de) 1998-11-15

Family

ID=9449318

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94401632T ATE172721T1 (de) 1993-07-16 1994-07-13 Aminosäurederivate und ihre verwendung als enkephalinase-inhibitoren

Country Status (8)

Country Link
US (2) US5612371A (de)
EP (1) EP0634396B1 (de)
JP (1) JP3584496B2 (de)
AT (1) ATE172721T1 (de)
DE (1) DE69414194T2 (de)
DK (1) DK0634396T3 (de)
ES (1) ES2124861T3 (de)
FR (1) FR2707638B1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760241A (en) * 1995-12-28 1998-06-02 Zambon Group S.P.A. Thiol derivatives with metallopeptidase inhibitory activity
FR2772027B1 (fr) * 1997-12-10 2000-02-04 Fournier Ind & Sante Procede de preparation asymetrique de derives de l'acide 2-mercaptomethyl-3-phenyl-propanoique, utilisation pour synthese de principes actifs chiraux
US6056363A (en) * 1997-12-29 2000-05-02 Maddox; Lee W. Reclining computer chair apparatus
DE69906849T2 (de) * 1998-02-16 2004-01-22 Ajinomoto Co., Inc. Verfahren zur Herstellung von optisch aktiven Phenylpropionsäure-Derivat
US6303799B1 (en) * 1998-11-10 2001-10-16 Naxcor Polynucleotide crosslinking agents
US6562995B1 (en) 2000-12-21 2003-05-13 Beacon Laboratories, Inc. Delta dicarbonyl compounds and methods for using the same
KR101664642B1 (ko) 2003-09-29 2016-10-11 가부시키가이샤 니콘 노광장치, 노광방법 및 디바이스 제조방법
US7022627B2 (en) 2003-10-31 2006-04-04 Asm International N.V. Method for the heat treatment of substrates
US6883250B1 (en) * 2003-11-04 2005-04-26 Asm America, Inc. Non-contact cool-down station for wafers
US6940047B2 (en) * 2003-11-14 2005-09-06 Asm International N.V. Heat treatment apparatus with temperature control system
KR100785270B1 (ko) 2006-09-08 2007-12-12 주식회사 대우일렉트로닉스 순간 가열 방식 스팀 청소기의 스팀 제어 장치
WO2021127642A1 (en) * 2019-12-19 2021-06-24 Massachusetts Institute Of Technology Selective valorization of biomass sugars

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
US4401677A (en) * 1981-10-09 1983-08-30 E. R. Squibb & Sons, Inc. Enkephalinase inhibitors
EP0136883B1 (de) * 1983-10-03 1987-11-25 E.R. Squibb & Sons, Inc. Enkephalinase Inhibitoren
US4722810A (en) * 1984-08-16 1988-02-02 E. R. Squibb & Sons, Inc. Enkephalinase inhibitors
FR2556721B1 (fr) * 1983-12-14 1986-05-16 Roussel Uclaf Nouveaux derives de o-mercaptopropanamide d'o amino-acides, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
FR2652087B1 (fr) * 1989-09-15 1993-10-15 Bioprojet Ste Civile Derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques.

Also Published As

Publication number Publication date
EP0634396B1 (de) 1998-10-28
ES2124861T3 (es) 1999-02-16
DK0634396T3 (da) 1999-07-05
JP3584496B2 (ja) 2004-11-04
JPH07188158A (ja) 1995-07-25
DE69414194T2 (de) 1999-04-22
DE69414194D1 (de) 1998-12-03
US5646313A (en) 1997-07-08
US5612371A (en) 1997-03-18
FR2707638A1 (fr) 1995-01-20
EP0634396A1 (de) 1995-01-18
FR2707638B1 (fr) 1995-08-18

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee