ATE174689T1 - Diagnose und behandlung von insulinabhängigem diabetes mellitus - Google Patents
Diagnose und behandlung von insulinabhängigem diabetes mellitusInfo
- Publication number
- ATE174689T1 ATE174689T1 AT90908064T AT90908064T ATE174689T1 AT E174689 T1 ATE174689 T1 AT E174689T1 AT 90908064 T AT90908064 T AT 90908064T AT 90908064 T AT90908064 T AT 90908064T AT E174689 T1 ATE174689 T1 AT E174689T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- diabetes mellitus
- dependent diabetes
- insulin
- diagnosis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1289—Mycobacteriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/965—Chemistry: molecular biology and microbiology involving idiotype or anti-idiotype antibody
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Rehabilitation Therapy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32286489A | 1989-03-14 | 1989-03-14 | |
| US07/371,249 US5114844A (en) | 1989-03-14 | 1989-06-26 | Diagnosis and treatment of insulin dependent diabetes mellitus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE174689T1 true ATE174689T1 (de) | 1999-01-15 |
Family
ID=26983648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90908064T ATE174689T1 (de) | 1989-03-14 | 1990-03-14 | Diagnose und behandlung von insulinabhängigem diabetes mellitus |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US5114844A (de) |
| EP (1) | EP0417271B1 (de) |
| JP (3) | JP3165148B2 (de) |
| AT (1) | ATE174689T1 (de) |
| AU (1) | AU639456B2 (de) |
| CA (1) | CA2029861C (de) |
| DE (1) | DE69032833T2 (de) |
| FI (1) | FI103976B1 (de) |
| NO (1) | NO300594B1 (de) |
| WO (1) | WO1990010449A1 (de) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6001360A (en) * | 1988-12-13 | 1999-12-14 | University Of Florida | Method and compositions for early detection and treatment of insulin dependent diabetes mellitus |
| US5645998A (en) | 1988-12-13 | 1997-07-08 | University Of Florida Research Foundation | Methods and compositions for the early detection and treatment of insulin dependent diabetes mellitus |
| US5762937A (en) * | 1988-12-13 | 1998-06-09 | University Of Florida Research Foundation, Inc. | Methods and compositions for the early detection and treatment of insulin dependent diabetes mellitus |
| US5780034A (en) * | 1989-03-14 | 1998-07-14 | Yeda Research And Development Co. Ltd. | Diagnosis and treatment of insulin dependent diabetes mellitus using heat shock protein determinents |
| US5114844A (en) * | 1989-03-14 | 1992-05-19 | Yeda Research And Development Co., Ltd. | Diagnosis and treatment of insulin dependent diabetes mellitus |
| GB8919321D0 (en) * | 1989-08-25 | 1989-10-11 | Univ London | Treatment of chronic inflammatory conditions |
| US5427940A (en) * | 1991-06-03 | 1995-06-27 | Board Of Regents, The University Of Texas System | Engineered cells producing insulin in response to glucose |
| GB9007194D0 (en) * | 1990-03-30 | 1990-05-30 | Wellcome Found | Live vaccines |
| WO1992004632A1 (en) * | 1990-09-07 | 1992-03-19 | The Regents Of The University Of California | Methods for the diagnosis and treatment of diabetes |
| US5512447A (en) * | 1990-09-07 | 1996-04-30 | The Regents Of The University Of California | Methods for the diagnosis and treatment of diabetes |
| US5674978A (en) * | 1990-09-21 | 1997-10-07 | The Regents Of The University Of California | Peptides derived from glutamic acid decarboxylase |
| US5998366A (en) * | 1990-09-21 | 1999-12-07 | The Regents Of The University Of California | Method for ameliorating glutamic acid decarboxylase associated autoimmune disorders |
| US5620686A (en) * | 1990-09-28 | 1997-04-15 | British Technology Group Limited | Antigen-antibody conjugates |
| EP0559770A4 (en) * | 1990-11-26 | 1995-04-05 | Us Commerce | Cell stress transcriptional factors |
| US6174862B1 (en) * | 1991-04-22 | 2001-01-16 | Ramot University Authority For Applied Research And Industrial Development, Ltd. | Neurotrophic peptides of activity dependent neurotrophic factor |
| CA2109098C (en) * | 1991-04-22 | 2005-08-09 | Douglas E. Brenneman | Activity-dependent neurotrophic factor |
| JPH06508030A (ja) * | 1991-05-15 | 1994-09-14 | ザイモジェネティクス,インコーポレイティド | ヒトすい島グルタミン酸デカルボキシラーゼ自己抗原のクローニング及び発現 |
| WO1993009141A1 (en) | 1991-11-01 | 1993-05-13 | Joslin Diabetes Center | Antigen associated with type i diabetes mellitus |
| AT398495B (de) * | 1992-06-09 | 1994-12-27 | Wick Georg Dr | Diagnose oder vorhersage von atherosklerose |
| IL102687A (en) * | 1992-07-30 | 1997-06-10 | Yeda Res & Dev | Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them |
| AU4796393A (en) * | 1992-07-31 | 1994-03-03 | Immulogic Pharmaceutical Corporation | Sensitive assay for antigens and antibodies and its use to identify rheumatoid arthritis antigen |
| US5420108A (en) * | 1992-09-14 | 1995-05-30 | Shohet; Isaac H. | Method of controlling diabetes mellitus |
| US5872094A (en) * | 1993-01-06 | 1999-02-16 | The General Hospital Corporation | Method for attaching cartilaginous tissue, cartilage matrix protein or link protein to a surface |
| ES2171454T3 (es) | 1993-06-04 | 2002-09-16 | Whitehead Biomedical Inst | Proteinas de estres y sus usos. |
| US7008790B1 (en) | 1993-08-12 | 2006-03-07 | Classen Immunotherapies, Inc. | Method and composition for an early vaccine to protect against both common infectious diseases and chronic immune mediated disorders or their sequelae |
| US5728385A (en) | 1993-08-12 | 1998-03-17 | Classen Immunotherapies, Inc. | Method and composition for an early vaccine to protect against both common infectious diseases and chronic immune mediated disorders or their sequelae |
| JPH09505588A (ja) | 1993-11-23 | 1997-06-03 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 多くの細胞外生成物及びそれらの製造法並びに使用 |
| US7300660B2 (en) | 1993-11-23 | 2007-11-27 | The Regents Of The University Of California | Abundant extracellular products and methods for their production and use |
| US6752993B1 (en) | 1993-11-23 | 2004-06-22 | The Regents Of The University Of California | Abundant extracellular product vaccines and methods for their production and use |
| US5863742A (en) * | 1994-03-10 | 1999-01-26 | Chiron Diagnostics Corporation | Inhibition of protease activity of human whole blood cell lysates |
| WO1995025744A1 (en) * | 1994-03-21 | 1995-09-28 | Rijksuniversiteit Utrecht | Peptide fragments of microbial stress proteins and pharmaceutical composition made thereof for the treatment and prevention of inflammatory diseases |
| US5869058A (en) * | 1994-05-25 | 1999-02-09 | Yeda Research And Development Co. Ltd. | Peptides used as carriers in immunogenic constructs suitable for development of synthetic vaccines |
| US6509165B1 (en) | 1994-07-08 | 2003-01-21 | Trustees Of Dartmouth College | Detection methods for type I diabetes |
| MX9700198A (es) * | 1994-07-08 | 1997-04-30 | Dartmouth College | Compuestos peptidos de proinsulina para detectar y tratar diabetes tipo 1. |
| WO1996005223A1 (en) * | 1994-08-12 | 1996-02-22 | The Regents Of The University Of California | Abundant extracellular products and methods for their production and use |
| GB9419553D0 (en) * | 1994-09-27 | 1994-11-16 | Univ Bristol | Polypeptides and their use in the treatment of auto-immune disease |
| DK0820303T3 (da) * | 1994-12-21 | 2003-10-06 | Yeda Res & Dev | p277 peptidanaloger og farmaceutiske sammensætninger, der omfatter dem, til behandling eller diagnosticering af diabetes |
| IL112094A0 (en) * | 1994-12-21 | 1995-03-15 | Yeda Res & Dev | Novel peptides and pharmaceutical compositions comprising them |
| US6180103B1 (en) | 1994-12-21 | 2001-01-30 | Yeda Research And Development Co., Ltd. | Peptide p277 analogs, and pharmaceutical compositions comprising them for treatment or diagnosis of diabetes |
| IL114407A0 (en) * | 1995-06-30 | 1995-10-31 | Yeda Res & Dev | Novel peptides and pharmaceutical compositions comprising them |
| US20030190323A1 (en) * | 1995-07-05 | 2003-10-09 | Yeda Research And Development Co. Ltd. | Preparations and methods for the treatment of T cell mediated diseases |
| IL114458A0 (en) * | 1995-07-05 | 1995-11-27 | Yeda Res & Dev | Therapeutic preparations for treatment of T cell mediated diseases |
| US6488933B2 (en) | 1995-07-05 | 2002-12-03 | Yeda Research And Development Co. Ltd. | Preparations for the treatment of T cell mediated diseases |
| US6013660A (en) * | 1996-10-02 | 2000-01-11 | The Regents Of The University Of California | Externally targeted prophylactic and chemotherapeutic method and agents |
| US7157089B1 (en) | 1996-11-26 | 2007-01-02 | Stressgen Biotechnologies Corporation | Immune responses using compositions containing stress proteins |
| EP1047451A1 (de) * | 1997-02-18 | 2000-11-02 | Whitehead Institute For Biomedical Research | Verwendung von hitzeshockproteinen zur verabreichung von einheiten in zellen |
| NZ538399A (en) * | 1997-08-05 | 2007-05-31 | Nventa Biopharma Corp | Fusion protein comprising an HPV E7 protein and a stress protein wherein the E7 protein is joined directly to the amino terminus of the stress protein |
| US20020009448A1 (en) * | 1997-09-19 | 2002-01-24 | Leslie P. Weiner | T-cell vaccination for the treatment of multiple sclerosis |
| WO1999037315A1 (en) * | 1998-01-27 | 1999-07-29 | Bai Jane Pei Fan | Chemical derivatives of autoantigens and autoimmune-suppressive peptides and pharmaceutical composition containing the same |
| US7488476B2 (en) * | 1998-11-05 | 2009-02-10 | Hadasit Medical Research Services & Development Ltd. | B-cell epitope peptides of HSP 65, DNA encoding said peptides, antibodies directed against said peptides and the different uses thereof in the treatment of inflammatory and autoimmune diseases |
| AU759303B2 (en) * | 1998-11-05 | 2003-04-10 | Hadasit Medical Research Services & Development Company Ltd | Novel amino acid sequences, DNA encoding the amino acid sequences, antibodies directed against such sequences and the different uses thereof |
| US8158125B2 (en) * | 1998-11-05 | 2012-04-17 | Hadasit Medical Research Services & Development Ltd. | B-cell epitope peptides of HSP 65, novel amino acid sequences, DNA encoding the amino acid sequences of said peptides, antibodies directed against said peptides and different uses thereof in the treatment of inflammatory and autoimmune diseases |
| US6497880B1 (en) * | 1998-12-08 | 2002-12-24 | Stressgen Biotechnologies Corporation | Heat shock genes and proteins from Neisseria meningitidis, Candida glabrata and Aspergillus fumigatus |
| JP2003504074A (ja) | 1999-07-08 | 2003-02-04 | ストレスゲン バイオテクノロジーズ コーポレイション | インビトロでのTh1様応答の誘導 |
| IL150113A0 (en) * | 1999-12-15 | 2002-12-01 | Peptor Ltd | Fragments and antagonists of heat shock protein 60 |
| CA2396384A1 (en) * | 2000-01-14 | 2001-07-19 | Whitehead Institute For Biomedical Research | In vivo ctl elicitation by heat shock protein fusion proteins maps to a discrete atp binding domain and is cd4+ t cell-independent |
| US7541184B2 (en) | 2000-02-24 | 2009-06-02 | Invitrogen Corporation | Activation and expansion of cells |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| NZ523408A (en) | 2000-06-26 | 2006-02-24 | Stressgen Biotechnologies Corp | Human papilloma virus treatment |
| IL137460A0 (en) | 2000-07-24 | 2001-07-24 | Yeda Res & Dev | Identifying antigen clusters for monitoring a global state of an immune system |
| KR20030074787A (ko) | 2001-02-05 | 2003-09-19 | 스트레스젠 바이오테크놀러지스 코포레이션 | B형 간염 바이러스 치료 |
| WO2003063759A2 (en) * | 2002-01-31 | 2003-08-07 | Peptor Ltd. | Hsp peptides and analogs for modulation of immune responses via antigen presenting cells |
| US20050084967A1 (en) | 2002-06-28 | 2005-04-21 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
| AU2005207891B2 (en) * | 2004-01-28 | 2010-04-01 | Andromeda Biotech Ltd. | Hsp therapy in conjunction with a low antigenicity diet |
| US20050260770A1 (en) * | 2004-04-01 | 2005-11-24 | Cohen Irun R | Antigen array and diagnostic uses thereof |
| EP1835933A4 (de) * | 2005-01-04 | 2015-01-07 | Yeda Res & Dev | Hsp60, hsp60-peptide und t-zellen-impfstoffe zur immunmodulation |
| ES2389849T3 (es) | 2005-03-14 | 2012-11-02 | Yeda Research And Development Co., Ltd. | Ccomposiciones de péptidos HSP60 y antígenos víricos para vacunación y diagnóstico |
| CA2658678A1 (en) | 2005-08-06 | 2007-02-15 | Gerald J. Prud'homme | Composition and method for prevention and treatment of type i diabetes |
| WO2007116409A2 (en) | 2006-04-11 | 2007-10-18 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Improved vaccines comprising multimeric hsp60 peptide carriers |
| DE102006019127A1 (de) * | 2006-04-25 | 2007-10-31 | Carl Zeiss Meditec Ag | Multiwellenlängen-Lasersystem und Verfahren für ophthalmologische Anwendungen |
| EP2231180B1 (de) | 2008-01-16 | 2016-08-17 | Ben-gurion University Of The Negev Research And Development Authority | Impfstoff für die alzheimerkrankheit |
| WO2013128453A1 (en) | 2012-03-01 | 2013-09-06 | Yeda Research And Development Co. Ltd. | Regeneration of islet beta cells by hsp60 derived peptides |
| WO2013128450A1 (en) | 2012-03-01 | 2013-09-06 | Yeda Research And Development Co. Ltd. | Hsp60 derived peptides and peptide analogs for suppression and treatment of non-autoimmune diabetes |
| US10545144B2 (en) | 2013-12-31 | 2020-01-28 | Yeda Research And Development Co., Ltd. | Diagnosis of systemic lupus erythematosus using oligonucleotides antigens |
| EP3265814B1 (de) | 2015-03-01 | 2020-11-18 | Immunarray Ltd. | Diagnose von systemischem lupus erythematodes mithilfe von protein-, peptid- und oligonukleotidantigenen |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL8701163A (nl) * | 1986-09-09 | 1988-04-05 | Nederlanden Staat | Gebruik van een peptide voor de bereiding van preparaten voor het verlichten, het behandelen en de diagnose van autoimmuunziekten, in het bijzonder arthritische toestanden, verbindingen die met dit peptide verwant zijn, alsmede farmaceutische en diagnostische preparaten en testkits. |
| CA1320907C (en) * | 1986-09-23 | 1993-08-03 | Irun Robert Cohen | Cell membrane proteins, compositions containing them and procedure for their preparation |
| US4952395A (en) * | 1987-02-26 | 1990-08-28 | Scripps Clinic And Research Foundation | Mycobacterial recombinants and peptides |
| NL8703107A (nl) * | 1987-12-22 | 1989-07-17 | Nederlanden Staat | Polypeptiden en derivaten daarvan, alsmede de toepassing daarvan in farmaceutische en diagnostische preparaten. |
| IL85746A (en) * | 1988-03-15 | 1994-05-30 | Yeda Res & Dev | Preparations comprising t-lymphocyte cells treated with 8-methoxypsoralen or cell membranes separated therefrom for preventing or treating autoimmune diseases |
| US5114844A (en) * | 1989-03-14 | 1992-05-19 | Yeda Research And Development Co., Ltd. | Diagnosis and treatment of insulin dependent diabetes mellitus |
-
1989
- 1989-06-26 US US07/371,249 patent/US5114844A/en not_active Expired - Lifetime
-
1990
- 1990-03-14 JP JP50811690A patent/JP3165148B2/ja not_active Expired - Fee Related
- 1990-03-14 AT AT90908064T patent/ATE174689T1/de not_active IP Right Cessation
- 1990-03-14 EP EP90908064A patent/EP0417271B1/de not_active Expired - Lifetime
- 1990-03-14 AU AU55467/90A patent/AU639456B2/en not_active Expired
- 1990-03-14 CA CA002029861A patent/CA2029861C/en not_active Expired - Lifetime
- 1990-03-14 DE DE69032833T patent/DE69032833T2/de not_active Expired - Lifetime
- 1990-03-14 WO PCT/US1990/001397 patent/WO1990010449A1/en not_active Ceased
- 1990-11-13 NO NO904919A patent/NO300594B1/no not_active IP Right Cessation
- 1990-11-13 FI FI905614A patent/FI103976B1/fi active IP Right Grant
-
1993
- 1993-03-29 US US08/039,704 patent/US5671848A/en not_active Expired - Lifetime
-
1999
- 1999-07-26 JP JP21116199A patent/JP3203323B2/ja not_active Expired - Lifetime
-
2000
- 2000-05-29 JP JP2000157825A patent/JP2001010962A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NO300594B1 (no) | 1997-06-23 |
| JP3165148B2 (ja) | 2001-05-14 |
| WO1990010449A1 (en) | 1990-09-20 |
| NO904919L (no) | 1991-01-14 |
| EP0417271A1 (de) | 1991-03-20 |
| CA2029861C (en) | 2001-01-16 |
| US5671848A (en) | 1997-09-30 |
| JP2000055916A (ja) | 2000-02-25 |
| AU5546790A (en) | 1990-10-09 |
| JP2001010962A (ja) | 2001-01-16 |
| FI103976B (fi) | 1999-10-29 |
| EP0417271A4 (en) | 1992-09-09 |
| EP0417271B1 (de) | 1998-12-16 |
| JP3203323B2 (ja) | 2001-08-27 |
| AU639456B2 (en) | 1993-07-29 |
| CA2029861A1 (en) | 1990-09-15 |
| JPH04502920A (ja) | 1992-05-28 |
| NO904919D0 (no) | 1990-11-13 |
| US5114844A (en) | 1992-05-19 |
| DE69032833D1 (de) | 1999-01-28 |
| FI103976B1 (fi) | 1999-10-29 |
| DE69032833T2 (de) | 1999-05-12 |
| FI905614A0 (fi) | 1990-11-13 |
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