ATE174926T1 - Hydrophobe nukleinsäure-sonde - Google Patents

Hydrophobe nukleinsäure-sonde

Info

Publication number
ATE174926T1
ATE174926T1 AT90306980T AT90306980T ATE174926T1 AT E174926 T1 ATE174926 T1 AT E174926T1 AT 90306980 T AT90306980 T AT 90306980T AT 90306980 T AT90306980 T AT 90306980T AT E174926 T1 ATE174926 T1 AT E174926T1
Authority
AT
Austria
Prior art keywords
nucleic acid
acid probe
hydrophobic nucleic
polynucleotide
hydrophobic
Prior art date
Application number
AT90306980T
Other languages
English (en)
Inventor
Michael Urdea
Thomas Horn
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Application granted granted Critical
Publication of ATE174926T1 publication Critical patent/ATE174926T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT90306980T 1989-06-30 1990-06-26 Hydrophobe nukleinsäure-sonde ATE174926T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37446289A 1989-06-30 1989-06-30

Publications (1)

Publication Number Publication Date
ATE174926T1 true ATE174926T1 (de) 1999-01-15

Family

ID=23476935

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90306980T ATE174926T1 (de) 1989-06-30 1990-06-26 Hydrophobe nukleinsäure-sonde

Country Status (9)

Country Link
US (2) US5552280A (de)
EP (1) EP0405913B1 (de)
JP (1) JP2593245B2 (de)
AT (1) ATE174926T1 (de)
CA (1) CA2019939C (de)
DE (1) DE69032847T2 (de)
IE (1) IE902390A1 (de)
PT (1) PT94559B (de)
WO (1) WO1991000288A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5695926A (en) * 1990-06-11 1997-12-09 Bio Merieux Sandwich hybridization assays using very short capture probes noncovalently bound to a hydrophobic support
FR2679255B1 (fr) * 1991-07-17 1993-10-22 Bio Merieux Procede d'immobilisation d'un fragment nucleique par fixation passive sur un support solide, support solide ainsi obtenu et son utilisation.
US5976789A (en) * 1991-07-17 1999-11-02 Bio Merieux System of probes enabling HLA-DR typing to be performed, and typing method using said probes
US6391655B1 (en) 1997-07-30 2002-05-21 Corning Incorporated Oxidized styrenic polymers for DNA binding
BR9814271A (pt) * 1997-12-12 2001-03-20 Digene Corp Determinação de doenças relacionadas com o vìrus do papiloma humano
US6203989B1 (en) 1998-09-30 2001-03-20 Affymetrix, Inc. Methods and compositions for amplifying detectable signals in specific binding assays
DE60128086T2 (de) * 2000-02-07 2008-01-10 Dos Remedios, Cristobal Guillermo Biomolekularer toxizitätstest
US7601497B2 (en) * 2000-06-15 2009-10-13 Qiagen Gaithersburg, Inc. Detection of nucleic acids by target-specific hybrid capture method
US7439016B1 (en) 2000-06-15 2008-10-21 Digene Corporation Detection of nucleic acids by type-specific hybrid capture method
GB0016836D0 (en) 2000-07-07 2000-08-30 Lee Helen Improved dipstick assays (1)
US7297553B2 (en) 2002-05-28 2007-11-20 Nanosphere, Inc. Method for attachment of silylated molecules to glass surfaces
WO2003006676A2 (en) 2001-07-13 2003-01-23 Nanosphere, Inc. Method for immobilizing molecules onto surfaces
DK1778867T3 (da) 2004-07-01 2010-08-02 Gen Probe Inc Fremgangsmåder og sammensætninger til detektering af nucleinsyrer i en biologisk prøve
WO2009140374A2 (en) 2008-05-13 2009-11-19 Gen-Probe Incorporated Inactivatable target capture oligomers for use in the selective hybridization and capture of target nucleic acid sequences
TWI417389B (zh) 2008-10-27 2013-12-01 Qiagen Gaithersburg Inc 於自動平台上之快速結果雜交捕捉法
WO2010068473A1 (en) * 2008-11-25 2010-06-17 Gen-Probe Incorporated Compositions and methods for detecting small rnas, and uses thereof
EP2385979B1 (de) * 2009-01-28 2017-08-16 QIAGEN Gaithersburg, Inc. Sequenzspezifisches verfahren zur vorbereitung grossvolumiger proben und assay
AU2010242867B2 (en) 2009-05-01 2016-05-12 Qiagen Gaithersburg, Inc. A non-target amplification method for detection of RNA splice-forms in a sample
JP5826752B2 (ja) 2009-09-14 2015-12-02 キアジェン ゲイサーズバーグ インコーポレイテッド 細胞学用培地に固定された組織サンプルから核酸またはタンパク質を回収するための組成物および方法
ES2615728T3 (es) * 2010-01-29 2017-06-08 Qiagen Gaithersburg, Inc. Métodos y composiciones para una purificación y un análisis múltiple específico de secuencia de ácidos nucleicos
CA2787781A1 (en) 2010-01-29 2011-08-04 Qiagen Gaithersburg, Inc. Method of determining and confirming the presence of an hpv in a sample
US9422593B2 (en) 2010-05-19 2016-08-23 Qiagen Gaithresburg, Inc Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
AU2012220575B2 (en) 2011-02-24 2017-01-12 Qiagen Gaithersburg, Inc. Materials and methods for detection of HPV nucleic acid

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2334107A1 (fr) * 1975-12-05 1977-07-01 Pasteur Institut Procede de couplage de substances biologiques par des liaisons covalentes
US4379843A (en) * 1981-01-26 1983-04-12 Peter Cashion Immobilization of polynucleotides and polypeptides with tritylated polysaccharides
US4493899A (en) * 1981-10-16 1985-01-15 City Of Hope Method of testing for particular antibodies in the serum of a patient
US4455370A (en) * 1982-05-17 1984-06-19 E. I. Du Pont De Nemours And Company Transferring separated components in gel electrophoresis via nylon membrane
US5217492A (en) * 1982-09-29 1993-06-08 Bio-Metric Systems, Inc. Biomolecule attachment to hydrophobic surfaces
US4588682A (en) * 1982-12-13 1986-05-13 Integrated Genetics, Inc. Binding nucleic acid to a support
YU43849B (en) * 1983-08-09 1989-12-31 Akad Wissenschaften Process for preparing macromolecular substances with chemically active filling substances
US4806546A (en) * 1985-09-30 1989-02-21 Miles Inc. Immobilization of nucleic acids on derivatized nylon supports
US4868105A (en) * 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
US4777120A (en) * 1987-05-18 1988-10-11 Eastman Kodak Company Photographic element and process comprising a masking coupler
US5354657A (en) * 1988-01-12 1994-10-11 Boehringer Mannheim Gmbh Process for the highly specific detection of nucleic acids in solid
DE3824110A1 (de) * 1988-07-15 1990-01-18 Max Planck Gesellschaft Verfahren zur herstellung und reinigung von an ihrem 5'-ende phosphorylierten oligo- und jpolynukleotidsequenzen und reagenz zur durchfuehrung des verfahrens
DK0462145T3 (da) * 1989-03-07 1994-08-08 Genentech Inc Covalente konjugater mellem lipid og oligonucleotid

Also Published As

Publication number Publication date
CA2019939C (en) 2000-05-23
PT94559A (pt) 1991-04-18
PT94559B (pt) 1997-07-31
EP0405913A2 (de) 1991-01-02
IE902390L (en) 1990-12-30
JP2593245B2 (ja) 1997-03-26
US5702893A (en) 1997-12-30
DE69032847D1 (de) 1999-02-04
EP0405913A3 (en) 1991-10-09
JPH05500749A (ja) 1993-02-18
WO1991000288A1 (en) 1991-01-10
CA2019939A1 (en) 1990-12-31
IE902390A1 (en) 1991-06-19
US5552280A (en) 1996-09-03
DE69032847T2 (de) 1999-05-12
EP0405913B1 (de) 1998-12-23

Similar Documents

Publication Publication Date Title
DE69032847D1 (de) Hydrophobe Nukleinsäure-Sonde
NL194922B (nl) Werkwijze voor de bepaling van nucleïnezuren, alsmede set daarvoor.
DK0517796T3 (da) Oligonukleotid-analoger
PT693065E (pt) Derivados de cumarina nao-nucleosidicos como agentes reticulantes de polionucleotidos
FI881497A7 (fi) Nopea hybridisaatiomääritysmenetelmä, jossa käytetään lateksiin immobilisoitua sensoria.
ATE70048T1 (de) Selektive amidinierung von diaminen.
FI891524A7 (fi) Polynukleotidien määritys, jolloin käytetään oligonukleotideja estämää n ei-toivotut sivureaktiot
DE3581377D1 (de) Vorrichtung zum erzeugen von reinem wasser.
IT8723222A0 (it) Scocca per autovetture.
DE3767331D1 (de) Zusammensetzung fuer haertende anstrichfarben.
FI852625A7 (fi) Menetelmä kaksisäikeisten nukleiinihappomolekyylien muodostamiseksi yksisäikeisistä nukleiinihappomolekyyleistä.
NO852659L (no) Drivmekanisme for slagmaskin.
BR8705000A (pt) Processo de polimerizacao de transferencia de grupo
DE3770543D1 (de) Vorrichtung zum praezisionsplazieren von wagen.
DE3889749D1 (de) Verfahren zum Vervielfältigen von Pflanzensämlingen.
DK335583A (da) 7alfa-acylthio-15,16-methylen-3-oxo-17alfa-pregna-1,4-dien-21,17-carbolactoner samt fremgangsmaade til fremstilling heraf
DE3784792D1 (de) Biochemisches verfahren.
FI874961A7 (fi) Menetelmä nukleiinihappohybridien toteamiseksi.
ATE78598T1 (de) Immunassay unter benutzung der mikropartikelneutralisierung.
ES2019364B3 (es) Proceso de produccion de tinta.
IT8121234A0 (it) Processo per la produzione di l-alanina usando microorganismi immobilizzati.
FI883162A7 (fi) Nukleiinihappojohdannaisia.
IT8121236A0 (it) Processo per la produzione di l-aminoacidi usando microorganismi immobilizzati.
IT7820684A0 (it) Processo per la preparazione di 6 isobornil 3,4 xilenolo.
IT7824949A0 (it) Processo per la produzione dicomposti organici alifatici difunzionali.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties