ATE175355T1 - Stabilisiertes somatotropin zur parenteralen verabreichung - Google Patents

Stabilisiertes somatotropin zur parenteralen verabreichung

Info

Publication number
ATE175355T1
ATE175355T1 AT93915333T AT93915333T ATE175355T1 AT E175355 T1 ATE175355 T1 AT E175355T1 AT 93915333 T AT93915333 T AT 93915333T AT 93915333 T AT93915333 T AT 93915333T AT E175355 T1 ATE175355 T1 AT E175355T1
Authority
AT
Austria
Prior art keywords
somatotropin
stabilized
parenteral administration
complex
animals
Prior art date
Application number
AT93915333T
Other languages
English (en)
Inventor
Michael Thomas Clark
Robert J Gyurik
Sharon K Lewis
Marianne C Murray
Matthew J Raymond
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE175355T1 publication Critical patent/ATE175355T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Fodder In General (AREA)
  • Medicinal Preparation (AREA)
  • Feed For Specific Animals (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cultivation Of Plants (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT93915333T 1992-06-11 1993-06-11 Stabilisiertes somatotropin zur parenteralen verabreichung ATE175355T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/896,958 US5198422A (en) 1992-06-11 1992-06-11 Stabilized somatotropin for parenteral administration

Publications (1)

Publication Number Publication Date
ATE175355T1 true ATE175355T1 (de) 1999-01-15

Family

ID=25407118

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93915333T ATE175355T1 (de) 1992-06-11 1993-06-11 Stabilisiertes somatotropin zur parenteralen verabreichung

Country Status (20)

Country Link
US (1) US5198422A (de)
EP (1) EP0644770B1 (de)
JP (1) JP3247380B2 (de)
KR (1) KR100269896B1 (de)
CN (1) CN1069214C (de)
AT (1) ATE175355T1 (de)
AU (1) AU670805B2 (de)
CA (1) CA2137677C (de)
DE (1) DE69322958T2 (de)
DK (1) DK0644770T3 (de)
ES (1) ES2125990T3 (de)
GR (1) GR3029291T3 (de)
HU (1) HU223944B1 (de)
IL (1) IL105958A (de)
NO (1) NO314784B1 (de)
NZ (1) NZ253914A (de)
PL (1) PL175971B1 (de)
TW (1) TW341513B (de)
WO (1) WO1993025222A1 (de)
ZA (1) ZA934100B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA949350B (en) 1994-01-25 1996-05-24 Upjohn Co Aqueous prolonged release formulation
KR19990071255A (ko) 1998-02-28 1999-09-15 성재갑 소마토트로핀과 비타민의 합제 조성물
ID27131A (id) * 1998-06-26 2001-03-01 Pfizer Prod Inc Proses yang lebih baik untuk membuat hasil adisi basa schiff dari amina dengan o-hidroksi aldehida dan komposisi materi yang didasarkan padanya
US20080113025A1 (en) * 1998-11-02 2008-05-15 Elan Pharma International Limited Compositions comprising nanoparticulate naproxen and controlled release hydrocodone
JP2001316294A (ja) * 2000-03-14 2001-11-13 Pfizer Prod Inc ｏ−バニリンおよびｏ−バニリン／テトラメチルクロマニルカルボン酸化合物の組み合わせの使用法
CN100369953C (zh) * 2002-09-09 2008-02-20 尼克塔治疗亚拉巴马公司 水溶性聚合物链烷醛
CA2512052C (en) 2002-12-31 2016-06-21 Altus Pharmaceuticals Inc. Human growth hormone crystals and methods for preparing them
JP2006523609A (ja) * 2002-12-31 2006-10-19 アルタス ファーマシューティカルズ インコーポレイテッド タンパク質結晶およびイオン性ポリマーの複合体
TWI429436B (zh) * 2007-04-10 2014-03-11 Helsinn Therapeutics Us Inc 使用生長激素促泌素治療或預防嘔吐之方法
CA2963784A1 (en) 2007-06-08 2008-12-18 Mannkind Corporation Ire-1.alpha. inhibitors
ITMI20130341A1 (it) 2013-03-07 2014-09-08 Gm Morando S R L Sistema schermante modulare
WO2017131214A1 (ja) * 2016-01-29 2017-08-03 日産化学工業株式会社 水溶性有効成分の放出が制御された経皮吸収組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1296253C (en) * 1986-10-20 1992-02-25 Praveen Tyle Stabilized growth hormone compositions
EP0374120A3 (de) * 1988-12-13 1991-07-31 Monsanto Company Zusammensetzung mit kontrollierter Wirkstoffabgabe von Polypeptiden
US5015627A (en) * 1990-07-20 1991-05-14 Smithkline Beecham Corporation Stabilized somatotropin for parenteral administration

Also Published As

Publication number Publication date
IL105958A0 (en) 1993-10-20
AU670805B2 (en) 1996-08-01
HUT68917A (en) 1995-08-28
NO944782L (no) 1994-12-09
DK0644770T3 (da) 1999-08-30
IL105958A (en) 1997-11-20
NO944782D0 (no) 1994-12-09
CN1069214C (zh) 2001-08-08
JPH07508003A (ja) 1995-09-07
DE69322958D1 (de) 1999-02-18
ES2125990T3 (es) 1999-03-16
NZ253914A (en) 1997-12-19
PL175971B1 (pl) 1999-03-31
NO314784B1 (no) 2003-05-26
JP3247380B2 (ja) 2002-01-15
TW341513B (en) 1998-10-01
CN1085804A (zh) 1994-04-27
HU223944B1 (hu) 2005-03-29
ZA934100B (en) 1994-06-10
AU4535493A (en) 1994-01-04
HU9403548D0 (en) 1995-02-28
KR100269896B1 (ko) 2000-10-16
GR3029291T3 (en) 1999-05-28
CA2137677A1 (en) 1993-12-23
CA2137677C (en) 1998-08-25
WO1993025222A1 (en) 1993-12-23
EP0644770A4 (de) 1995-10-25
EP0644770A1 (de) 1995-03-29
EP0644770B1 (de) 1999-01-07
US5198422A (en) 1993-03-30
DE69322958T2 (de) 1999-05-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee