ATE175978T1 - Verwendung von spezifischen molekülen zur steigerung der igf-1 aktivität - Google Patents

Verwendung von spezifischen molekülen zur steigerung der igf-1 aktivität

Info

Publication number
ATE175978T1
ATE175978T1 AT93919457T AT93919457T ATE175978T1 AT E175978 T1 ATE175978 T1 AT E175978T1 AT 93919457 T AT93919457 T AT 93919457T AT 93919457 T AT93919457 T AT 93919457T AT E175978 T1 ATE175978 T1 AT E175978T1
Authority
AT
Austria
Prior art keywords
activity
igf
specific molecules
increase igf
antibodies
Prior art date
Application number
AT93919457T
Other languages
English (en)
Inventor
Jennifer Margaret Pell
Peter Charles Bates
Claire Elisabeth Hamil Stewart
Original Assignee
Biotech & Biolog Scien Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotech & Biolog Scien Res filed Critical Biotech & Biolog Scien Res
Application granted granted Critical
Publication of ATE175978T1 publication Critical patent/ATE175978T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dental Preparations (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT93919457T 1992-08-20 1993-08-20 Verwendung von spezifischen molekülen zur steigerung der igf-1 aktivität ATE175978T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929217696A GB9217696D0 (en) 1992-08-20 1992-08-20 Use of specific binding molecules

Publications (1)

Publication Number Publication Date
ATE175978T1 true ATE175978T1 (de) 1999-02-15

Family

ID=10720662

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93919457T ATE175978T1 (de) 1992-08-20 1993-08-20 Verwendung von spezifischen molekülen zur steigerung der igf-1 aktivität

Country Status (8)

Country Link
EP (1) EP0656908B1 (de)
AT (1) ATE175978T1 (de)
AU (1) AU674697B2 (de)
CA (1) CA2141861A1 (de)
DE (1) DE69323204D1 (de)
GB (1) GB9217696D0 (de)
NZ (1) NZ255461A (de)
WO (1) WO1994004569A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9501472D0 (sv) * 1995-04-21 1995-04-21 Pharmacia Ab Truncated IGF-I
US20030069177A1 (en) 2000-05-16 2003-04-10 Genentech, Inc. Method for treating cartilage disorders
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
US6420518B1 (en) 1997-04-04 2002-07-16 Genetech, Inc. Insulin-like growth factor agonist molecules
DE60042550D1 (de) 1999-01-06 2009-08-27 Genentech Inc Mutierte varianten des insulin-ähnlichen wachstumsfaktor i (igf-i)
CA2356109C (en) 1999-01-06 2008-04-22 Genentech, Inc. Insulin-like growth factor (igf) i mutant variants
US6040292A (en) * 1999-06-04 2000-03-21 Celtrix Pharmaceuticals, Inc. Methods for treating diabetes
DK1265630T3 (da) 2000-03-24 2006-10-09 Genentech Inc Anvendelse af insulin til behandling af brusksygdomme
CN100439397C (zh) 2001-02-09 2008-12-03 基因技术股份有限公司 Igf-1的结晶
US7071300B2 (en) 2001-03-14 2006-07-04 Genentech, Inc. IGF antagonist peptides
WO2004039845A1 (en) * 2002-10-31 2004-05-13 Universita'degli Studi Di Roma 'la Sapienza' Antimicrobial lipase antibodies their nucleotide and aminoacid sequences and uses thereof
DK2274978T3 (en) 2003-09-12 2015-06-15 Ipsen Biopharmaceuticals Inc Methods of treating an insulin-like growth factor-I (IGF-I) deficiency
WO2005028515A1 (ja) 2003-09-24 2005-03-31 Kyowa Hakko Kogyo Co., Ltd. ヒトインスリン様成長因子に対する遺伝子組換え抗体
EP1802333A2 (de) 2004-09-13 2007-07-04 Arrowsmith Technologies LLP In-vivo-antikörperpufferung eines liganden
CA2637707A1 (en) 2006-02-02 2007-08-09 Rinat Neuroscience Corporation Methods for treating obesity by administering a trkb antagonist
KR100861914B1 (ko) * 2006-03-06 2008-10-09 (주)케어젠 인슐린 유사 성장인자―１의 활성을 가지는 펩타이드 및그의 용도
WO2010146059A2 (en) 2009-06-16 2010-12-23 F. Hoffmann-La Roche Ag Biomarkers for igf-1r inhibitor therapy
KR101669140B1 (ko) 2015-04-28 2016-10-26 (주)케어젠 항비만 및 항당뇨 효능을 갖는 펩타이드 및 이의 용도
WO2021005604A1 (en) 2019-07-11 2021-01-14 Opko Biologics Ltd. Long-acting igf-1 or igf-1 variants and methods of producing same

Also Published As

Publication number Publication date
AU674697B2 (en) 1997-01-09
GB9217696D0 (en) 1992-09-30
EP0656908A1 (de) 1995-06-14
DE69323204D1 (de) 1999-03-04
CA2141861A1 (en) 1994-03-03
EP0656908B1 (de) 1999-01-20
WO1994004569A1 (en) 1994-03-03
AU4967393A (en) 1994-03-15
NZ255461A (en) 1996-12-20

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