ATE176243T1 - Pacap-derivate mit c-amp-produzierenden eigenschaften - Google Patents

Pacap-derivate mit c-amp-produzierenden eigenschaften

Info

Publication number
ATE176243T1
ATE176243T1 AT92114102T AT92114102T ATE176243T1 AT E176243 T1 ATE176243 T1 AT E176243T1 AT 92114102 T AT92114102 T AT 92114102T AT 92114102 T AT92114102 T AT 92114102T AT E176243 T1 ATE176243 T1 AT E176243T1
Authority
AT
Austria
Prior art keywords
group
lys
substituted
leu
val
Prior art date
Application number
AT92114102T
Other languages
English (en)
Inventor
Chieko Kitada
Takuya Watanabe
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE176243T1 publication Critical patent/ATE176243T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT92114102T 1991-08-22 1992-08-19 Pacap-derivate mit c-amp-produzierenden eigenschaften ATE176243T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21116191 1991-08-22

Publications (1)

Publication Number Publication Date
ATE176243T1 true ATE176243T1 (de) 1999-02-15

Family

ID=16601412

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92114102T ATE176243T1 (de) 1991-08-22 1992-08-19 Pacap-derivate mit c-amp-produzierenden eigenschaften

Country Status (5)

Country Link
US (2) US5623050A (de)
EP (1) EP0529487B1 (de)
AT (1) ATE176243T1 (de)
CA (1) CA2076593C (de)
DE (1) DE69228277T2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996034958A1 (en) * 1995-05-03 1996-11-07 Biostar Inc. Vasoactive intestinal peptide
US6037321A (en) * 1995-05-03 2000-03-14 Biostar Inc. Fusion proteins comprising vasoactive intestinal peptide or PACAP
US6017533A (en) * 1996-04-25 2000-01-25 Shiseido Company, Ltd. Peptides having specific affinity to pituitary adenylate cyclase activating polypeptide type 1 receptors
PL345583A1 (en) * 1998-07-20 2001-12-17 Sod Conseils Rech Applic Peptide analogues of pacap
US6242563B1 (en) 1998-07-20 2001-06-05 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Peptide analogues
AR036400A1 (es) 2001-08-30 2004-09-08 Stem Cell Therapeutics Inc Regulacion combinada de la produccion de celulas nerviosas.
ATE541921T1 (de) * 2001-09-14 2012-02-15 Stem Cell Therapeutics Inc Prolaktin-induzierte zunahme an neuronalen stammzellen und dessen therapeutische anwendung
US20030054551A1 (en) * 2001-09-18 2003-03-20 Stem Cell Therapeutics Inc. Effect of growth hormone and IGF-1 on neural stem cells
JP4783013B2 (ja) 2002-07-30 2011-09-28 ステム セル セラピューティクス インコーポレイテッド 多能性神経幹細胞からの希突起神経膠細胞産生
CA2492442A1 (en) * 2002-07-31 2004-02-05 Stem Cell Therapeutics Inc. Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (pacap)
EP1571155B1 (de) * 2002-11-27 2011-08-24 Ils Inc. Peptide und medizinische zusammensetzungen mit denselben
CA2556266A1 (en) 2004-02-13 2005-08-25 Stem Cell Therapeutics Corp. Use of luteinizing hormone (lh), and chorionic gonadotropin (hcg) for proliferation of neural stem cells and neurogenesis
CA2582567A1 (en) * 2004-10-07 2006-04-13 Stem Cell Therapeutics Corp. Stimulation of proliferation of pluripotential stem cells through administration of pregnancy associated compounds
US7007328B1 (en) * 2004-11-05 2006-03-07 Terry Bailey System and apparatus for upper body support of a recumbent person
WO2007036033A1 (en) 2005-09-27 2007-04-05 Stem Cell Therapeutics Corp. Oligodendrocyte precursor cell proliferation regulated by prolactin
WO2007106987A1 (en) * 2006-03-17 2007-09-27 Stem Cell Therapeutics Corp. Continuous dosing regimens for neural stem cell proliferating agents and neural stem cell differentiating agents
EP2519633B1 (de) 2009-12-29 2017-10-25 CuRNA, Inc. Behandlung von erkrankungen im zusammenhang mit dem nuclear-respirator-faktor 1 (nrf1) mittels hemmung des natürlichen antisense-transkripts gegen nrf1
EP3712164A4 (de) * 2017-11-14 2021-08-18 Senju Pharmaceutical Co., Ltd. Pacap-stabilisiertes peptid

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562175A (en) * 1984-02-03 1985-12-31 Ding Chang Synthetic peptides
US4605641A (en) * 1984-10-09 1986-08-12 Hoffmann-La Roche Inc. Synthetic vasoactive intestinal peptide analogs
JPS62246595A (ja) * 1986-04-17 1987-10-27 Eisai Co Ltd 気菅支拡張作用・降圧作用ペプタイド
US5128242A (en) * 1989-06-19 1992-07-07 The Administrators Of The Tulane Educational Fund Hypothalamic polypeptides with adenylate cyclase stimulating activity
US5198542A (en) * 1989-06-20 1993-03-30 Takeda Chemical Industries, Inc. Dna encoding a pitvitary adenylate cyclase activating protein and use thereof
EP0467279A3 (en) * 1990-07-18 1992-08-05 Takeda Chemical Industries, Ltd. Polypeptides having c-amp producing activity

Also Published As

Publication number Publication date
US5801147A (en) 1998-09-01
DE69228277T2 (de) 1999-07-08
EP0529487A2 (de) 1993-03-03
CA2076593A1 (en) 1993-02-23
US5623050A (en) 1997-04-22
CA2076593C (en) 2002-06-04
EP0529487A3 (en) 1994-06-22
EP0529487B1 (de) 1999-01-27
DE69228277D1 (de) 1999-03-11

Similar Documents

Publication Publication Date Title
ATE176243T1 (de) Pacap-derivate mit c-amp-produzierenden eigenschaften
HU895678D0 (en) Process for the preparation of novel insulin derivatives and pharmaceutical compositions containing such active ingredient
ATE129409T1 (de) Neue verwendung von peptidderivat.
PH27425A (en) Insulin derivatives the use thereof and a pharmaceutical formulation containing them
CA2085495A1 (en) Isoxyanatocarboxylic acids, a process for their preparation and their use in coating compositions as cross-linking agents
NZ240189A (en) Aryl substituted amides, carbamates, carbonates, ketones and esters; preparation and pharmaceutical/cosmetic compositions thereof
EP0254080A3 (en) Malonic acid derivatives and methods for their synthesis
HUT61004A (en) Process for producing quinoxaline derivatives and pharmaceutical compositions comprising such compounds as active ingredient
EP0548024A3 (de)
HUT55034A (en) Process for producing peptides with hemoregulating effect and pharmaceutical compositions comprising such compounds as active ingredient
KR880009934A (ko) 피리딘-2,4-및 2,5-디카복실산 유도체, 이의 제조방법, 이의 용도 및 이들 화합물을 기본으로 하는 약제
ATE166205T1 (de) Tb-wirksame carbonsäure
ATE121726T1 (de) Hydroquinonester von aminosäuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische oder kosmetische zusammensetzungen.
IL86638A0 (en) (2-cyano-2-oximinoacetyl)-amino acid derivatives,their preparation and their use as pesticides
IL86637A0 (en) (2-cyano-2-oximinoacetyl)-amino acid derivatives,their preparation and their use as pesticides
EP0309971A3 (de) Pergualinähnliche Verbindungen und pharmazeutisches Mittel
IE781545L (en) Benzimidazole-2-derivatives.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties