ATE176779T1 - Verfahren zur herstellung von d-chiro inositol - Google Patents

Verfahren zur herstellung von d-chiro inositol

Info

Publication number: ATE176779T1
Authority: AT; Austria
Prior art keywords: chiro; inositol; resin; type; column packed
Prior art date: 1993-08-11

Application number

AT94923085T

Other languages

English (en)

Inventor

Kiyoshi Sato

Makoto Yoshida

Kenji Kanbe

Kiyoshi Hirazawa

Tomio Takeuchi

Original Assignee

Hokko Chem Ind Co

Zaidan Hojin Biseibutsu

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-08-11

Filing date

1994-08-08

Publication date

1999-03-15

1993-08-11 Priority claimed from JP5217926A external-priority patent/JP3053510B2/ja

1993-10-26 Priority claimed from JP05288827A external-priority patent/JP3113770B2/ja

1994-07-04 Priority claimed from JP06152181A external-priority patent/JP3113776B2/ja

1994-08-08 Application filed by Hokko Chem Ind Co, Zaidan Hojin Biseibutsu filed Critical Hokko Chem Ind Co

1999-03-15 Application granted granted Critical

1999-03-15 Publication of ATE176779T1 publication Critical patent/ATE176779T1/de

Links

CDAISMWEOUEBRE-LKPKBOIGSA-N 1D-chiro-inositol Chemical compound O[C@H]1[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O CDAISMWEOUEBRE-LKPKBOIGSA-N 0.000 title abstract 7
CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 title abstract 7
238000004519 manufacturing process Methods 0.000 title 1
230000002378 acidificating effect Effects 0.000 abstract 5
239000000243 solution Substances 0.000 abstract 4
NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 3
239000007864 aqueous solution Substances 0.000 abstract 3
238000006243 chemical reaction Methods 0.000 abstract 3
239000003456 ion exchange resin Substances 0.000 abstract 3
229920003303 ion-exchange polymer Polymers 0.000 abstract 3
239000011347 resin Substances 0.000 abstract 3
229920005989 resin Polymers 0.000 abstract 3
230000000694 effects Effects 0.000 abstract 2
PVTHJAPFENJVNC-MHRBZPPQSA-N kasugamycin Chemical compound N[C@H]1C[C@H](NC(=N)C(O)=O)[C@@H](C)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O PVTHJAPFENJVNC-MHRBZPPQSA-N 0.000 abstract 2
239000013078 crystal Substances 0.000 abstract 1
230000008021 deposition Effects 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000007935 neutral effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic
- C07C35/08—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing a six-membered rings
- C07C35/14—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing a six-membered rings with more than one hydroxy group bound to the ring
- C07C35/16—Inositols
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
- C07C29/10—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)

AT94923085T 1993-08-11 1994-08-08 Verfahren zur herstellung von d-chiro inositol ATE176779T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP5217926A JP3053510B2 (ja)	1993-08-11	1993-08-11	Ｄ−キロ−イノシトールの製造法
JP05288827A JP3113770B2 (ja)	1993-10-26	1993-10-26	Ｄ−キロ−イノシトールの製造方法
JP06152181A JP3113776B2 (ja)	1994-07-04	1994-07-04	Ｄ−キロ−イノシトールの製造方法

Publications (1)

Publication Number	Publication Date
ATE176779T1 true ATE176779T1 (de)	1999-03-15

Family

ID=27320233

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94923085T ATE176779T1 (de)	1993-08-11	1994-08-08	Verfahren zur herstellung von d-chiro inositol

Country Status (11)

Country	Link
US (1)	US5714643A (de)
EP (1)	EP0712827B1 (de)
KR (1)	KR100332144B1 (de)
CN (1)	CN1072637C (de)
AT (1)	ATE176779T1 (de)
CA (1)	CA2168953A1 (de)
DE (1)	DE69416594T2 (de)
DK (1)	DK0712827T3 (de)
ES (1)	ES2130440T3 (de)
TW (1)	TW350837B (de)
WO (1)	WO1995004711A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5932774A (en) *	1995-11-06	1999-08-03	Abbott Laboratories	Processes for the preparation of D-chiro-inositol
EP0790970B1 (de) *	1994-11-10	1999-06-09	Abbott Laboratories	Verbessertes verfahren zur herstellung von d-chiroinositol
JP2001215294A (ja) *	1999-11-22	2001-08-10	Japan Organo Co Ltd	復水脱塩装置
US6342645B2 (en) *	1999-12-30	2002-01-29	Insmed Pharmaceuticals, Inc.	Methods for the production and isolation of D-chiro-inositol from kasugamycin and the use of D-chiro-inositol obtained therefrom
US6660891B2 (en)	2000-05-15	2003-12-09	Insmed Incorporated	Methods for the production of D-chiro-inositol and the use of D-chiro inositol obtained therefrom
US6408277B1 (en) *	2000-06-21	2002-06-18	Banter Limited	System and method for automatic task prioritization
US7521481B2 (en)	2003-02-27	2009-04-21	Mclaurin Joanne	Methods of preventing, treating and diagnosing disorders of protein aggregation
EP1824496A4 (de) *	2004-11-17	2008-07-16	Joanne Mclaurin	Zusammensetzungen aus scyllo-inositol-derivaten und verfahren zur behandlung von störungen der proteinaggregation
WO2007041855A1 (en) *	2005-10-13	2007-04-19	Waratah Pharmaceuticals, Inc.	Scyllo-inositol derivatives and their use in the treatment of diseases characterised by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence
US20070197452A1 (en) *	2006-02-17	2007-08-23	Mclaurin Joanne	Treatment of amyloid-related diseases
CN103054837A (zh) *	2006-03-09	2013-04-24	瓦拉塔药品公司	用于治疗蛋白积聚病症的环己烷多元醇制剂
US20110028719A1 (en) *	2006-05-19	2011-02-03	Jacek Slon-Usakiewicz	Screening methods for amyloid beta modulators
US20100173960A1 (en) *	2006-09-21	2010-07-08	Antonio Cruz	The Combination of a Cyclohexanehexol and a NSAID for the Treatment of Neurodegenerative Diseases
US20110218176A1 (en)	2006-11-01	2011-09-08	Barbara Brooke Jennings-Spring	Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
US20080103116A1 (en) *	2006-11-01	2008-05-01	Jennings-Spring Barbara L	Method of treatment and compositions of D-chiro inositol and phosphates thereof
US20090214474A1 (en) *	2006-11-01	2009-08-27	Barbara Brooke Jennings	Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
WO2008061373A1 (en) *	2006-11-24	2008-05-29	Waratah Pharmaceuticals Inc.	Combination treatments for alzheimer's disease and similar diseases
JP2010523602A (ja) *	2007-04-12	2010-07-15	ワラタファーマシューティカルズ，インコーポレイテッド	眼疾患の治療におけるシクロヘキサンヘキソール誘導体の使用
CA2683580A1 (en) *	2007-04-12	2008-10-23	Joanne Mclaurin	Treatment of amyotrophic lateral sclerosis
CA2683546A1 (en) *	2007-04-12	2008-10-23	Joanne Mclaurin	Use of cyclohexanehexol derivatives in the treatment of .alpha.-synucleinopathies
WO2008124930A1 (en) *	2007-04-12	2008-10-23	Joanne Mclaurin	Use of cyclohexanehexol derivatives for the treatment of polyglutamine diseases
CA2740124A1 (en) *	2008-10-09	2010-04-15	Waratah Pharmaceuticals Inc.	Use of scyllo-inositols for the treatment of macular degeneration-related disorders
KR101447579B1 (ko)	2012-09-26	2014-10-15	주식회사 디와이내츄럴	미생물을 이용한 ｄ-카이로 이노시톨의 생산 방법
CN104961628A (zh) *	2015-06-30	2015-10-07	天津科技大学	一种由d-松醇转化为d-手性肌醇的方法
CN105669376B (zh) *	2016-02-27	2019-03-12	诸城市浩天药业有限公司	制备高结晶度、粒径大的肌醇的结晶工艺及应用
WO2019123718A1 (ja) *	2017-12-21	2019-06-27	オルガノ株式会社	非水液状物質の精製方法及び外気遮断部材付きイオン交換樹脂充填カートリッジ
WO2020225665A1 (en) *	2019-05-03	2020-11-12	Bono & Ditta S.P.A.	Process for the separation of pinitol from a carob extract
DE102022004733A1 (de)	2022-12-15	2024-06-20	Forschungszentrum Jülich GmbH	Genetisch modifizierter Mikroorganismus und dessen Verwendung zur Herstellung von D-Chiro-Inositol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS572381B2 (de) *	1974-11-18	1982-01-16
US5091596A (en) *	1990-12-20	1992-02-25	Univ. Of Va. Alumni Patents Foundation	Method for producing chiro-inositol

1994
- 1994-08-08 DE DE69416594T patent/DE69416594T2/de not_active Expired - Fee Related
- 1994-08-08 WO PCT/JP1994/001304 patent/WO1995004711A1/ja not_active Ceased
- 1994-08-08 DK DK94923085T patent/DK0712827T3/da active
- 1994-08-08 CA CA002168953A patent/CA2168953A1/en not_active Abandoned
- 1994-08-08 AT AT94923085T patent/ATE176779T1/de not_active IP Right Cessation
- 1994-08-08 KR KR1019960700719A patent/KR100332144B1/ko not_active Expired - Fee Related
- 1994-08-08 EP EP94923085A patent/EP0712827B1/de not_active Expired - Lifetime
- 1994-08-08 US US08/596,131 patent/US5714643A/en not_active Expired - Fee Related
- 1994-08-08 ES ES94923085T patent/ES2130440T3/es not_active Expired - Lifetime
- 1994-08-08 CN CN94193030A patent/CN1072637C/zh not_active Expired - Fee Related
- 1994-09-02 TW TW083108097A patent/TW350837B/zh active

Also Published As

Publication number	Publication date
ES2130440T3 (es)	1999-07-01
WO1995004711A1 (en)	1995-02-16
KR100332144B1 (ko)	2002-11-13
EP0712827A4 (de)	1996-11-06
DE69416594D1 (de)	1999-03-25
KR960703836A (ko)	1996-08-31
EP0712827A1 (de)	1996-05-22
CA2168953A1 (en)	1995-02-16
DE69416594T2 (de)	1999-09-23
US5714643A (en)	1998-02-03
CN1128986A (zh)	1996-08-14
TW350837B (en)	1999-01-21
EP0712827B1 (de)	1999-02-17
DK0712827T3 (da)	1999-09-20
CN1072637C (zh)	2001-10-10

Legal Events

Date	Code	Title	Description
1999-11-15	UEP	Publication of translation of european patent specification
2004-05-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69416594D1 (de)	1999-03-25	Verfahren zur herstellung von d-chiro inositol
WO1992007648A3 (en)	1992-11-26	Electro-synthesis of alcohols and carboxylic acids from corresponding metal salts
EP0151470A3 (en)	1986-07-30	Process for the recovery of citric acid
US3961034A (en)	1976-06-01	Method of removing sodium thiosulfate from a hydrosulfite reaction mixture
YU82487A (en)	1988-04-30	Process for producing aldehydes
ATE334219T1 (de)	2006-08-15	Verfahren zur reinigung von 1,3-propandiol aus einem fermentationsmedium
DE3260280D1 (en)	1984-08-02	Process for the preparation of isosorbid-5-nitrate
DE3778993D1 (de)	1992-06-17	Verfahren zur herstellung von silizium-tetrafluorid.
JPS5715885A (en)	1982-01-27	Method for recovery of high-purity waste water of washing
JPS6261592A (ja)	1987-03-18	塩基性アミノ酸の分離方法
IE64034B1 (en)	1995-06-28	Process for the recovery of citric acid from liquors containing it
DE68904692D1 (de)	1993-03-18	Herstellungsverfahren von cyclohexanol.
EP0483831A3 (en)	1993-01-13	Process for separating an organic acid or acids from an organic acid-containing solution
DE58902856D1 (de)	1993-01-14	Verfahren zur herstellung von o-substituierten hydroxylaminen.
MY150524A (en)	2014-01-30	Improved process for recovering hydrogen in producing pure terephthalic acid
ES483766A1 (es)	1980-05-16	Procedimiento de recuperacion de acidos carboxilicos
EP0213736B1 (de)	1990-09-26	Methode zur Trennung von Glycin und L-Serin aus einer Lösung die diese enthält
US3393233A (en)	1968-07-16	Method for recovering ethylene diamine tetraacetic acid
ATE29130T1 (de)	1987-09-15	Verfahren zur kontinuierlichen herstelllung von einer alpha-amino-saeure durch katalytische chemische hydrolyse und apparat fuer dieses verfahren.
JPS62255453A (ja)	1987-11-07	バリンの分離精製法
JP3881044B2 (ja)	2007-02-14	グリコール酸水溶液の製造法
JPS62195339A (ja)	1987-08-28	常温におけるメタンのメタノ−ルへの転換
ATE145404T1 (de)	1996-12-15	Verfahren zur reinigung von pentostatin
JP2767755B2 (ja)	1998-06-18	α―メチルスチレンの精製方法
JP2667956B2 (ja)	1997-10-27	ヘテロポリ酸塩系触媒からの触媒成分の回収方法