ATE177636T1 - Transdermale behandlung der nesselsucht mit optisch reinem (+)-cetirizin - Google Patents
Transdermale behandlung der nesselsucht mit optisch reinem (+)-cetirizinInfo
- Publication number
- ATE177636T1 ATE177636T1 AT94910260T AT94910260T ATE177636T1 AT E177636 T1 ATE177636 T1 AT E177636T1 AT 94910260 T AT94910260 T AT 94910260T AT 94910260 T AT94910260 T AT 94910260T AT E177636 T1 ATE177636 T1 AT E177636T1
- Authority
- AT
- Austria
- Prior art keywords
- cetirizine
- optically pure
- treatment
- hurts
- useful
- Prior art date
Links
- ZKLPARSLTMPFCP-NRFANRHFSA-N 2-[2-[4-[(s)-(4-chlorophenyl)-phenylmethyl]piperazin-1-ium-1-yl]ethoxy]acetate Chemical compound C1CN(CCOCC(=O)O)CCN1[C@H](C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-NRFANRHFSA-N 0.000 title abstract 3
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 abstract 2
- 208000036284 Rhinitis seasonal Diseases 0.000 abstract 2
- 201000009961 allergic asthma Diseases 0.000 abstract 2
- 201000010105 allergic rhinitis Diseases 0.000 abstract 2
- 208000006673 asthma Diseases 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 208000017022 seasonal allergic rhinitis Diseases 0.000 abstract 2
- ZKLPARSLTMPFCP-UHFFFAOYSA-N Cetirizine Chemical compound C1CN(CCOCC(=O)O)CCN1C(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-UHFFFAOYSA-N 0.000 abstract 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 206010014950 Eosinophilia Diseases 0.000 abstract 1
- 208000030852 Parasitic disease Diseases 0.000 abstract 1
- 206010039094 Rhinitis perennial Diseases 0.000 abstract 1
- 206010052568 Urticaria chronic Diseases 0.000 abstract 1
- 206010046751 Urticaria physical Diseases 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 229960001803 cetirizine Drugs 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 208000024376 chronic urticaria Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000013764 eosinophil chemotaxis Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000022719 perennial allergic rhinitis Diseases 0.000 abstract 1
- 201000002881 physical urticaria Diseases 0.000 abstract 1
- 230000001932 seasonal effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95091092A | 1992-09-24 | 1992-09-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE177636T1 true ATE177636T1 (de) | 1999-04-15 |
Family
ID=25491013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94910260T ATE177636T1 (de) | 1992-09-24 | 1993-09-22 | Transdermale behandlung der nesselsucht mit optisch reinem (+)-cetirizin |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5627183A (de) |
| EP (2) | EP0661975B1 (de) |
| JP (1) | JPH08501562A (de) |
| AT (1) | ATE177636T1 (de) |
| AU (1) | AU5136193A (de) |
| CA (1) | CA2145413A1 (de) |
| DE (1) | DE69324025T2 (de) |
| DK (1) | DK0661975T3 (de) |
| ES (1) | ES2128556T3 (de) |
| GR (1) | GR3029927T3 (de) |
| WO (1) | WO1994006430A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5831066A (en) | 1988-12-22 | 1998-11-03 | The Trustees Of The University Of Pennsylvania | Regulation of bcl-2 gene expression |
| ES2122042T3 (es) * | 1992-09-24 | 1998-12-16 | Sepracor Inc | Tratamiento de rinitis alergica y asma que emplea (-)cetirizina. |
| GB9305282D0 (en) * | 1993-03-15 | 1993-05-05 | Ucb Sa | Enantiomers of 1-(4-chlorophenyl)phenylmethyl)-4-(4-methylphenyl)sulphonyl)piperazine |
| US6469009B1 (en) | 1996-04-08 | 2002-10-22 | Ucb, S.A. | Pharmaceutical compositions for the treatment of rhinitis |
| EP0811374A1 (de) * | 1996-05-29 | 1997-12-10 | Pfizer Inc. | Formulierung für ein Kombinationspräparat mit Cetirizin und Pseudoephedrin |
| IN188720B (de) * | 1997-11-06 | 2002-11-02 | Panacea Biotec Ltd | |
| US6432961B1 (en) * | 1998-08-18 | 2002-08-13 | Ucb S.A. | Method for preventing the onset of asthma |
| US6762347B1 (en) * | 1999-07-12 | 2004-07-13 | James Giovannoni | NOR gene compositions and methods for use thereof |
| US20030125308A1 (en) * | 1999-12-28 | 2003-07-03 | Yukiko Inamoto | Antipruritic agents for external use |
| US6258814B1 (en) * | 2000-10-13 | 2001-07-10 | Schering Corporation | Method of using cetirizine and pharmaceutical compositions containing the same for inducing sleep |
| US6596686B2 (en) | 2001-03-12 | 2003-07-22 | International Flavors & Fragrances Inc. | Use of dihydropyrans as fragrance Material |
| WO2004069338A1 (en) * | 2003-01-31 | 2004-08-19 | Schering Corporation | Use of combinations of h1 and h3 histamine receptor antagonists for the preparation of a medicament for the treatment of allergic skin and allergic ocular conditions |
| GB2403655A (en) * | 2003-07-11 | 2005-01-12 | Cipla Ltd | Combined pharmaceutical product comprising a beta-2 adrenoreceptor agonist & an antihistamine for treatment of respiratory diseases such as asthma |
| WO2005077371A1 (en) * | 2004-02-12 | 2005-08-25 | Ucb Farchim Sa | Use of levocetirizine for the preparation of a drug |
| US8513259B2 (en) | 2009-07-03 | 2013-08-20 | Jdp Therapeutics, Inc. | Non-sedating antihistamine injection formulations and methods of use thereof |
| US8263581B2 (en) | 2009-07-03 | 2012-09-11 | Jdp Therapeutics, Inc. | Non-sedating antihistamine injection formulations and methods of use thereof |
| US11253513B2 (en) | 2019-10-07 | 2022-02-22 | Jdp Therapeutics Llc | Dosing regimen for injectable cetirizine |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI75816C (fi) * | 1981-02-06 | 1988-08-08 | Ucb Sa | Foerfarande foer framstaellning av terapeutiskt aktiv 2-/4-(difenylmetyl)-1-piperazinyl/-aettiksyror eller dess amid. |
| US4829064A (en) * | 1987-06-08 | 1989-05-09 | Analgesic Associates | Cough/cold mixtures comprising non-sedating antihistamine drugs |
| GB8827390D0 (en) * | 1988-11-23 | 1988-12-29 | Ucb Sa | Process for preparation of 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-pipera-zinyl)ethoxy)-acetic acid & its dihydrochloride |
| GB8827391D0 (en) * | 1988-11-23 | 1988-12-29 | Ucb Sa | Process for preparation of 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-pipera-zinyl)ethoxy)-acetic acid & its dihydrochloride |
| ES2122042T3 (es) * | 1992-09-24 | 1998-12-16 | Sepracor Inc | Tratamiento de rinitis alergica y asma que emplea (-)cetirizina. |
| GB9305282D0 (en) * | 1993-03-15 | 1993-05-05 | Ucb Sa | Enantiomers of 1-(4-chlorophenyl)phenylmethyl)-4-(4-methylphenyl)sulphonyl)piperazine |
-
1993
- 1993-09-22 ES ES94910260T patent/ES2128556T3/es not_active Expired - Lifetime
- 1993-09-22 WO PCT/US1993/008999 patent/WO1994006430A1/en not_active Ceased
- 1993-09-22 DE DE69324025T patent/DE69324025T2/de not_active Expired - Fee Related
- 1993-09-22 AT AT94910260T patent/ATE177636T1/de not_active IP Right Cessation
- 1993-09-22 EP EP94910260A patent/EP0661975B1/de not_active Expired - Lifetime
- 1993-09-22 JP JP6508428A patent/JPH08501562A/ja active Pending
- 1993-09-22 CA CA002145413A patent/CA2145413A1/en not_active Abandoned
- 1993-09-22 DK DK94910260T patent/DK0661975T3/da active
- 1993-09-22 EP EP98115519A patent/EP0885611A3/de not_active Withdrawn
- 1993-09-22 AU AU51361/93A patent/AU5136193A/en not_active Abandoned
-
1996
- 1996-03-26 US US08/622,617 patent/US5627183A/en not_active Expired - Lifetime
-
1999
- 1999-04-07 GR GR990401020T patent/GR3029927T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0661975B1 (de) | 1999-03-17 |
| CA2145413A1 (en) | 1994-03-31 |
| ES2128556T3 (es) | 1999-05-16 |
| EP0885611A2 (de) | 1998-12-23 |
| US5627183A (en) | 1997-05-06 |
| JPH08501562A (ja) | 1996-02-20 |
| EP0661975A1 (de) | 1995-07-12 |
| DK0661975T3 (da) | 1999-09-27 |
| AU5136193A (en) | 1994-04-12 |
| GR3029927T3 (en) | 1999-07-30 |
| EP0885611A3 (de) | 1999-01-07 |
| WO1994006430A1 (en) | 1994-03-31 |
| DE69324025D1 (de) | 1999-04-22 |
| DE69324025T2 (de) | 1999-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |