ATE178601T1 - Neue benzopyranderivate - Google Patents
Neue benzopyranderivateInfo
- Publication number
- ATE178601T1 ATE178601T1 AT93902526T AT93902526T ATE178601T1 AT E178601 T1 ATE178601 T1 AT E178601T1 AT 93902526 T AT93902526 T AT 93902526T AT 93902526 T AT93902526 T AT 93902526T AT E178601 T1 ATE178601 T1 AT E178601T1
- Authority
- AT
- Austria
- Prior art keywords
- represent
- hydroxy
- new
- hydrogen
- benzopyrane derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1081992 | 1992-01-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE178601T1 true ATE178601T1 (de) | 1999-04-15 |
Family
ID=11760967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93902526T ATE178601T1 (de) | 1992-01-24 | 1993-01-25 | Neue benzopyranderivate |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5646308A (de) |
| EP (1) | EP0632033B1 (de) |
| JP (1) | JP3260458B2 (de) |
| KR (1) | KR100217167B1 (de) |
| CN (1) | CN1036918C (de) |
| AT (1) | ATE178601T1 (de) |
| AU (1) | AU3367393A (de) |
| CA (1) | CA2128603A1 (de) |
| DE (1) | DE69324354T2 (de) |
| DK (1) | DK0632033T3 (de) |
| ES (1) | ES2132217T3 (de) |
| GR (1) | GR3030581T3 (de) |
| SG (1) | SG52734A1 (de) |
| WO (1) | WO1993015068A1 (de) |
| ZA (1) | ZA93436B (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428031A (en) * | 1991-12-03 | 1995-06-27 | Merck & Co., Inc. | Methods of treating cardiac arrhythmia |
| DE69422038T2 (de) * | 1993-04-23 | 2000-09-14 | Chugai Seiyaku K.K., Tokio/Tokyo | Benzopyranderivate |
| US5719155A (en) * | 1993-11-10 | 1998-02-17 | Japan Tobacco Inc. | Chroman derivative and pharmaceutical use thereof |
| CA2195974C (en) * | 1994-08-18 | 2000-12-05 | David A. Claremon | 2,3-dihydro-1-(2,2,2-trifluoroethyl)-2-oxo-5-phenyl-1h-1,4-benzodiazepines |
| US5726171A (en) * | 1995-06-07 | 1998-03-10 | Merck & Co Inc | N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo B! 1,4!diazepin-3yl)-acetamides |
| US5691331A (en) * | 1995-06-07 | 1997-11-25 | Merck & Co., Inc. | N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides |
| US5700797A (en) * | 1995-06-07 | 1997-12-23 | Merck & Co, Inc. | N-(2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)-3-amides |
| JPH11506760A (ja) * | 1995-06-07 | 1999-06-15 | メルク エンド カンパニー インコーポレーテッド | 新規なｎ−（２，４−ジオキソ−２，３，４，５−テトラヒドロ−１ｈ−１，５−ベンゾジアゼピン−３イル）−３−アミド |
| US5631251A (en) * | 1995-06-07 | 1997-05-20 | Merck & Co., Inc. | 5-cyclopropyl-1,4 benzodiazepine-2-ones |
| US6218427B1 (en) * | 1996-08-27 | 2001-04-17 | Shionogi & Co., Ltd. | Chromene-3-carboxylate derivatives |
| FR2756284B1 (fr) * | 1996-11-26 | 2000-04-28 | Adir | Nouveaux derives du benzopyrane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| TW533073B (en) * | 1997-03-03 | 2003-05-21 | Chugai Pharmaceutical Co Ltd | Therapeutic agents for peripheral vascular disease |
| US6218411B1 (en) * | 1997-08-08 | 2001-04-17 | Chugai Seiyaku Kabushiki Kaisha | Therapeutics for diabetic complications |
| KR20010085866A (ko) * | 1998-09-30 | 2001-09-07 | 나가야마 오사무 | 4-치환 벤조피란 유도체의 제조법 |
| CZ20013076A3 (cs) * | 2000-08-29 | 2002-04-17 | Kuraray Co., Ltd. | Způsob výroby chromankarboxylové kyseliny |
| KR100602191B1 (ko) * | 2004-03-10 | 2006-07-19 | 한국화학연구원 | 5-라이폭시게네이즈 저해활성을 가지는2,2'-이중치환-3,4-디하이드로-7,8-이중치환-6-알킬아미노벤조피란 유도체 |
| JP2007536302A (ja) * | 2004-05-05 | 2007-12-13 | エフ．ホフマン−ラ ロシュ アーゲー | ５−ｈｔ６受容体、５−ｈｔ２ａ受容体、又はその両方の調節に有用なアリールスルホニルベンゾジオキサン類 |
| MX2007000911A (es) | 2004-07-30 | 2007-04-12 | Torrent Pharmaceuticals Ltd | Nevibolol y sus sales farmaceuticamente aceptables, proceso para su preparacion y composiciones farmaceuticas de nevibolol. |
| EP1831203A1 (de) | 2004-12-21 | 2007-09-12 | F. Hoffmann-Roche AG | Chromanderivate und deren anwendungen bei der behandlung von zns-erkrankungen |
| RU2388748C2 (ru) * | 2004-12-21 | 2010-05-10 | Ф. Хоффманн-Ля Рош Аг | Производные тетралина и индана и их применения в качестве антагонистов 5-нт |
| MX2007007481A (es) * | 2004-12-21 | 2007-07-20 | Hoffmann La Roche | Derivados de tetralina e indano y usos de los mismos. |
| SI1831159T1 (sl) * | 2004-12-21 | 2010-04-30 | Hoffmann La Roche | Derivati tetralina in indana ter njune uporabe |
| CN101124212A (zh) * | 2004-12-21 | 2008-02-13 | 弗·哈夫曼-拉罗切有限公司 | 色满衍生物及其作为5-ht受体配体的用途 |
| KR100704009B1 (ko) * | 2005-08-30 | 2007-04-04 | 한국화학연구원 | 염증억제 활성을 가지는6-알킬아미노-2-메틸-2'-(ｎ-메틸치환술폰아미도)메틸-2ｈ-1-벤조피란 유도체 |
| DE602006020351D1 (en) * | 2005-11-03 | 2011-04-07 | Hoffmann La Roche | Arylsulfonylchromane als 5-ht6-inhibitoren |
| BRPI0713502A2 (pt) * | 2006-06-20 | 2012-03-13 | F. Hoffmann-La Roche Ag | derivados de tetralina de arilsulfonamidil e empregos destes |
| EP2035370A2 (de) * | 2006-06-20 | 2009-03-18 | F. Hoffmann-Roche AG | Tetralin- und indanderivate und ihre verwendung |
| AU2007263076A1 (en) * | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Arylsulfonyl naphthalene derivatives and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH619701A5 (de) * | 1975-08-07 | 1980-10-15 | Bayer Ag | |
| JPS57167981A (en) * | 1981-04-08 | 1982-10-16 | Kowa Co | Benzopyran derivative |
| GB8911280D0 (en) * | 1989-05-17 | 1989-07-05 | Beecham Group Plc | Novel compounds |
| ATE161254T1 (de) * | 1990-07-27 | 1998-01-15 | Chugai Pharmaceutical Co Ltd | Benzopyranderivat |
-
1993
- 1993-01-21 ZA ZA93436A patent/ZA93436B/xx unknown
- 1993-01-22 JP JP00942193A patent/JP3260458B2/ja not_active Expired - Fee Related
- 1993-01-22 CN CN93102056A patent/CN1036918C/zh not_active Expired - Fee Related
- 1993-01-25 DE DE69324354T patent/DE69324354T2/de not_active Expired - Fee Related
- 1993-01-25 SG SG1996008501A patent/SG52734A1/en unknown
- 1993-01-25 AT AT93902526T patent/ATE178601T1/de not_active IP Right Cessation
- 1993-01-25 CA CA002128603A patent/CA2128603A1/en not_active Abandoned
- 1993-01-25 KR KR1019940702541A patent/KR100217167B1/ko not_active Expired - Fee Related
- 1993-01-25 US US08/256,580 patent/US5646308A/en not_active Expired - Fee Related
- 1993-01-25 EP EP93902526A patent/EP0632033B1/de not_active Expired - Lifetime
- 1993-01-25 ES ES93902526T patent/ES2132217T3/es not_active Expired - Lifetime
- 1993-01-25 WO PCT/JP1993/000086 patent/WO1993015068A1/ja not_active Ceased
- 1993-01-25 DK DK93902526T patent/DK0632033T3/da active
- 1993-01-25 AU AU33673/93A patent/AU3367393A/en not_active Abandoned
-
1999
- 1999-06-22 GR GR990401664T patent/GR3030581T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69324354D1 (de) | 1999-05-12 |
| EP0632033B1 (de) | 1999-04-07 |
| US5646308A (en) | 1997-07-08 |
| JPH05294954A (ja) | 1993-11-09 |
| EP0632033A1 (de) | 1995-01-04 |
| AU3367393A (en) | 1993-09-01 |
| GR3030581T3 (en) | 1999-10-29 |
| KR950700277A (ko) | 1995-01-16 |
| KR100217167B1 (ko) | 1999-09-01 |
| ES2132217T3 (es) | 1999-08-16 |
| DE69324354T2 (de) | 1999-11-25 |
| JP3260458B2 (ja) | 2002-02-25 |
| ZA93436B (en) | 1993-08-25 |
| CN1077954A (zh) | 1993-11-03 |
| CA2128603A1 (en) | 1993-08-05 |
| EP0632033A4 (de) | 1995-02-01 |
| SG52734A1 (en) | 1998-09-28 |
| CN1036918C (zh) | 1998-01-07 |
| DK0632033T3 (da) | 1999-10-18 |
| WO1993015068A1 (fr) | 1993-08-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |