ATE178618T1 - Herstellung von hydroxamsäurederivaten - Google Patents

Herstellung von hydroxamsäurederivaten

Info

Publication number: ATE178618T1
Authority: AT; Austria
Prior art keywords: acid derivatives; hydroxamic acid; production; hydrogen; formula
Prior art date: 1995-02-24

Application number

AT96903152T

Other languages

English (en)

Inventor

Christopher David Floyd

Christopher Norman Lewis

Original Assignee

British Biotech Pharm

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-02-24

Filing date

1996-02-26

Publication date

1999-04-15

1996-02-26 Application filed by British Biotech Pharm filed Critical British Biotech Pharm

1999-04-15 Application granted granted Critical

1999-04-15 Publication of ATE178618T1 publication Critical patent/ATE178618T1/de

Links

239000002253 acid Substances 0.000 title abstract 3
NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 title abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 abstract 2
239000007795 chemical reaction product Substances 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
239000007787 solid Substances 0.000 abstract 2
238000003746 solid phase reaction Methods 0.000 abstract 2
239000000758 substrate Substances 0.000 abstract 2
230000015572 biosynthetic process Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
238000006303 photolysis reaction Methods 0.000 abstract 1
230000015843 photosynthesis, light reaction Effects 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000006239 protecting group Chemical group 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/003—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by transforming the C-terminal amino acid to amides
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Analytical Chemistry (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Polymers & Plastics (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

AT96903152T 1995-02-24 1996-02-26 Herstellung von hydroxamsäurederivaten ATE178618T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9503749.5A GB9503749D0 (en)	1995-02-24	1995-02-24	Synthesis of hydroxamic acid derivatives

Publications (1)

Publication Number	Publication Date
ATE178618T1 true ATE178618T1 (de)	1999-04-15

Family

ID=10770202

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96903152T ATE178618T1 (de)	1995-02-24	1996-02-26	Herstellung von hydroxamsäurederivaten

Country Status (7)

Country	Link
US (3)	US5932695A (de)
EP (1)	EP0811019B1 (de)
JP (1)	JPH11500620A (de)
AT (1)	ATE178618T1 (de)
DE (1)	DE69602016T2 (de)
GB (1)	GB9503749D0 (de)
WO (1)	WO1996026223A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998015525A1 (en) *	1996-10-07	1998-04-16	Sumitomo Pharmaceuticals Co., Ltd.	Hydroxamic acids
US6281245B1 (en)	1996-10-28	2001-08-28	Versicor, Inc.	Methods for solid-phase synthesis of hydroxylamine compounds and derivatives, and combinatorial libraries thereof
AU5426398A (en)	1996-10-28	1998-05-22	Versicor Inc	Methods for solid-phase synthesis of hydroxylamine compounds and derivatives, and combinatorial libraries thereof
US6392010B1 (en) *	1996-12-19	2002-05-21	Aventis Pharmaceuticals Inc.	Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
US6133409A (en) *	1996-12-19	2000-10-17	Aventis Pharmaceuticals Products Inc.	Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
UA67733C2 (uk) *	1996-12-19	2004-07-15	Авентіс Фармасьютікалз Продактс Інк.	Спосіб твердофазного синтезу альдегідів, кетонів, оксимів, амінів і гідроксамової кислоти
ATE287885T1 (de)	1997-03-04	2005-02-15	Pharmacia Corp	Hydroxamsäure-sulfonamid-derivate mit amidiertem aromatischen ring
AU1589099A (en) *	1997-11-18	1999-06-07	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Functionalized resin for the synthesis of amides and peptides
CA2318487A1 (en) *	1998-01-09	1999-07-15	Sean Rees Klopfenstein	Solid supported synthesis of hydroxamic acids
US6569636B2 (en)	1998-05-29	2003-05-27	Hawaii Biotechnology Group, Inc.	Assay for modulators of metallo-enzyme activity
CA2337756A1 (en) *	1998-07-23	2000-02-03	Otto F. Schall	Libraries of polyhydroxamates and their analogs
US6291709B1 (en) *	1998-12-28	2001-09-18	The Procter & Gamble Company	Solid supported synthesis of hydroxamic acids
US6506936B1 (en) *	1999-02-25	2003-01-14	Fibrogen, Inc.	N-substituted arylsulfonylamino hydroxamic acids useful as inhibitors of c-proteinase and for treating or preventing disorders related to unregulated collagen production
GB9918684D0 (en) *	1999-08-09	1999-10-13	Novartis Ag	Organic compounds
US6797820B2 (en) *	1999-12-17	2004-09-28	Vicuron Pharmaceuticals Inc.	Succinate compounds, compositions and methods of use and preparation
DE10004565A1 (de) *	2000-02-02	2001-08-09	Merck Patent Gmbh	Alkalistabile Beschichtung auf Trägermaterialien
US7141607B1 (en)	2000-03-10	2006-11-28	Insite Vision Incorporated	Methods and compositions for treating and inhibiting retinal neovascularization
US6620882B1 (en)	2000-05-02	2003-09-16	Advanced Syntech, Llc	Solid support template for preparation of highly functionalized heterocycle compounds
GB0103303D0 (en) *	2001-02-09	2001-03-28	Novartis Ag	Organic compounds
WO2002072647A1 (en) *	2001-03-08	2002-09-19	The Regents Of The University Of California	Polyacrylamide medium for the electrophoretic separation of biomolecules
WO2002072790A2 (en)	2001-03-14	2002-09-19	Myriad Genetics, Inc	Tsg101-gag interaction and use thereof
US6608196B2 (en)	2001-05-03	2003-08-19	Galileo Pharmaceuticals, Inc.	Process for solid supported synthesis of pyruvate-derived compounds
US20040236519A1 (en) *	2001-06-08	2004-11-25	Marshall Garland R.	Libraries of confomationally constrained peptides, chiral azacrowns, and peptidomimetics and methods of making the same
KR101076018B1 (ko) *	2003-01-08	2011-10-21	유니버시티 오브 워싱톤	항균제
AU2005265093A1 (en)	2004-06-18	2006-01-26	Wyeth	Processes for preparing 6-alkyl-5-arylsulfonyl- dihydrophenanthridines
US7338775B1 (en)	2005-02-09	2008-03-04	Myriad Genetics, Inc.	Enzyme assay and use thereof
JP4775538B2 (ja) *	2005-02-28	2011-09-21	リンテック株式会社	光分解性高分子化合物
TWI519508B (zh) *	2007-06-12	2016-02-01	Achaogen Inc	抗菌劑
DE102009019852A1 (de)	2009-05-06	2010-11-11	Schebo Biotech Ag	Polymere mit neuen Strukturelementen, Verfahren zu ihrer Herstellung und ihre Verwendung
WO2013057186A1 (en)	2011-10-19	2013-04-25	Danmarks Tekniske Universitet	Photolabile linker for the synthesis of hydroxamic acids
EP2847168A1 (de)	2012-05-10	2015-03-18	Achaogen, Inc.	Antibakterielle wirkstoffe

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4461876A (en) *	1982-09-09	1984-07-24	Columbia University	Polymeric reagents for the isolation and protection of carbonyl compounds
GB8521192D0 (en) *	1985-08-23	1985-10-02	Courtaulds Plc	Polymeric carrier materials
US4868248A (en) *	1989-03-22	1989-09-19	Nalco Chemical Company	Polyhydroxyamic acid polymers from polyacrylic acids
EP0514648B2 (de) *	1991-05-23	2000-10-11	Cytec Technology Corp.	Microdispersionen von Polymeren mit Hydroxamsäuregruppen
FR2688788B1 (fr) *	1992-03-17	1994-05-13	Bio Merieux	Composes hydrosolubles derives d'un homopolymere ou copolymere de l'anhydride maleique, et applications desdits composes au support de molecules biologiques.

1995
- 1995-02-24 GB GBGB9503749.5A patent/GB9503749D0/en active Pending
1996
- 1996-02-26 US US08/809,499 patent/US5932695A/en not_active Expired - Fee Related
- 1996-02-26 JP JP8525514A patent/JPH11500620A/ja active Pending
- 1996-02-26 EP EP96903152A patent/EP0811019B1/de not_active Expired - Lifetime
- 1996-02-26 WO PCT/GB1996/000428 patent/WO1996026223A1/en not_active Ceased
- 1996-02-26 AT AT96903152T patent/ATE178618T1/de not_active IP Right Cessation
- 1996-02-26 DE DE69602016T patent/DE69602016T2/de not_active Expired - Fee Related
1999
- 1999-06-09 US US09/328,492 patent/US6093798A/en not_active Expired - Fee Related
- 1999-06-09 US US09/328,493 patent/US6228988B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPH11500620A (ja)	1999-01-19
US6228988B1 (en)	2001-05-08
GB9503749D0 (en)	1995-04-12
US6093798A (en)	2000-07-25
US5932695A (en)	1999-08-03
WO1996026223A1 (en)	1996-08-29
DE69602016D1 (de)	1999-05-12
EP0811019A1 (de)	1997-12-10
EP0811019B1 (de)	1999-04-07
DE69602016T2 (de)	1999-09-02

Legal Events

Date	Code	Title	Description
1999-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69602016D1 (de)	1999-05-12	Herstellung von hydroxamsäurederivaten
HUP9901894A2 (hu)	1999-09-28	Eljárás kurkuminnal rokon vegyületek előállítására
AU572018B2 (en)	1988-04-28	Thixotropic coating composition
TW363055B (en)	1999-07-01	Process for purifying crude (meth)acrylic acid
BR9916513A (pt)	2001-09-04	Composição de revestimento, e, processo para revestir substratos
UA35553C2 (uk)	2001-04-16	Спосіб отримання ароматичних сполук
NO20005714L (no)	2000-11-13	Nye substituerte cykliske forbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem
BG104767A (en)	2001-05-31	Process for preparing protected 4-aminomethyl-pyrrolidin-3-ones
ZA961170B (en)	1997-08-14	Preparation of biuret-containing polyisocyanates.
DE69920906D1 (de)	2004-11-11	Zwischenprodukte in der synthese von epothilonen und verfahren zu deren herstellung
NO975679L (no)	1998-02-02	Fremgangsmåte for fremstilling av N-monosubstituerte og N,N'-disubstituerte, usymmetriske, cykliske ureaer
DE69724141D1 (de)	2003-09-18	Verbindungen verwendbar zur perhaloalkylierung, reagenz für ihrer durchführung und verfahren zu ihrer herstellung
Hansen et al.	1995	Substrate acidities and conversion times for reactions of amides with di-tert-butyl bicarbonate
BR9803702A (pt)	2000-04-11	Processo para preparação de produtos de politriazina contendo grupos 2,2,6,6-tetrametil-4-piperidila.
MY106303A (en)	1995-04-29	Hydroxyimidazolines and polyamine fuel additive compositions
NZ335104A (en)	2000-10-27	Process for preparing hydroxamic acids from carboxylic acid intermediates for use as matrix metalloproteinase inhibitors
HUP9801200A2 (hu)	1998-09-28	NO-szintáz inhibitor hatással rendelkező argininanalógok, ezeket tartalmazó gyógyszerkészítmények és eljárás a vegyületek előállítására
AU5689790A (en)	1990-12-13	Reagents for rapid peptide synthesis
DK1432677T3 (da)	2008-06-16	Urinstofoligomerer, fremgangsmåde til fremstilling heraf og sammensætninger indeholdende disse
NO20002214D0 (no)	2000-04-28	FremgangsmÕte for syntese av pyrrolaminer
Köckritz et al.	1993	α-SUBSTITUTED PHOSPHONATES 68.1 α-AMINOPHOSPHONATES AND PHOSPHONO-SUBSTITUTED HETEROCYCLES FROM DIETHYL [2, 2, 2-TRICHLORO-1-ISOCYANATO-ETHYL] PHOSPHONATE
MX9804954A (es)	1998-09-30	Proceso para la preparacion de hidrazidas.
CA1264899C (en)	1990-01-23	SYNTHESIS OF PEPTIDES USING THIOXANTHYLMETHYLOXYCARBONYL DIOXIDES
SEKIZAKI et al.	1999	The structural requirements for an inverse substrate for enzymatic peptide synthesis: position isomers of guanidinonaphthyl esters as the acyl donor component
KR920703452A (ko)	1992-12-17	염화 칼슘과 아세틸렌의 제조를 위한 2-단 공정