ATE179211T1 - Menschliche il-3-varianten - Google Patents

Menschliche il-3-varianten

Info

Publication number
ATE179211T1
ATE179211T1 AT92921235T AT92921235T ATE179211T1 AT E179211 T1 ATE179211 T1 AT E179211T1 AT 92921235 T AT92921235 T AT 92921235T AT 92921235 T AT92921235 T AT 92921235T AT E179211 T1 ATE179211 T1 AT E179211T1
Authority
AT
Austria
Prior art keywords
pct
variants
human
sec
methods
Prior art date
Application number
AT92921235T
Other languages
English (en)
Inventor
Mathew Alexander Vadas
Angel Francisco Lopez
Mary Frances Shannon
Original Assignee
Medvet Science Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medvet Science Pty Ltd filed Critical Medvet Science Pty Ltd
Application granted granted Critical
Publication of ATE179211T1 publication Critical patent/ATE179211T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5403—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT92921235T 1991-10-07 1992-10-07 Menschliche il-3-varianten ATE179211T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPK874291 1991-10-07

Publications (1)

Publication Number Publication Date
ATE179211T1 true ATE179211T1 (de) 1999-05-15

Family

ID=3775735

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92921235T ATE179211T1 (de) 1991-10-07 1992-10-07 Menschliche il-3-varianten

Country Status (11)

Country Link
US (1) US5591427A (de)
EP (1) EP0609280B1 (de)
JP (1) JPH07501520A (de)
AT (1) ATE179211T1 (de)
AU (1) AU668364B2 (de)
CA (1) CA2120707A1 (de)
DE (1) DE69228997T2 (de)
DK (1) DK0609280T3 (de)
ES (1) ES2133329T3 (de)
GR (1) GR3030032T3 (de)
WO (1) WO1993007171A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586222B1 (en) 1989-08-16 2003-07-01 Chiron Corporation Recombinant PR-3 and compositions thereof
US5843693A (en) * 1989-08-16 1998-12-01 Chiron Corporation Assay method for screening for inhibitors of proTNF conversion
US5998378A (en) * 1989-08-16 1999-12-07 Chiron Corporation Compositions for the inhibition of TNF hormone formation and uses thereof
JPH08503706A (ja) * 1992-11-24 1996-04-23 ジー．ディー．サール アンド カンパニー インターロイキン−３（ｉｌ−３）多重変異ポリペプチド
US6153183A (en) * 1992-11-24 2000-11-28 G. D. Searle & Company Co-administration of interleukin-3 mutant polypeptides with CSF's or cytokines for multi-lineage hematopoietic cell production
US6413509B1 (en) * 1992-11-24 2002-07-02 S. Christopher Bauer Methods of ex-vivo expansion of hematopoietic cells using interleukin-3 mutant polypeptides with other hematopoietic growth factors
US7091319B1 (en) * 1992-11-24 2006-08-15 Bauer S Christopher IL-3 variant hematopoiesis fusion protein
US5772992A (en) * 1992-11-24 1998-06-30 G.D. Searle & Co. Compositions for co-administration of interleukin-3 mutants and other cytokines and hematopoietic factors
US6403076B1 (en) 1992-11-24 2002-06-11 S. Christopher Bauer Compositions for increasing hematopoiesis with interleukin-3 mutants
US6436387B1 (en) * 1992-11-24 2002-08-20 G.D. Searle & Co. Methods of ex-vivo expansion of hematopoietic cells using multivariant IL-3 hematopoiesis chimera proteins
US5738849A (en) * 1992-11-24 1998-04-14 G. D. Searle & Co. Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
US6361977B1 (en) * 1992-11-24 2002-03-26 S. Christopher Bauer Methods of using multivariant IL-3 hematopoiesis fusion protein
US6361976B1 (en) 1992-11-24 2002-03-26 S. Christopher Bauer Co-administration of interleukin-3 mutant polypeptides with CSF'S for multi-lineage hematopoietic cell production
US6057133A (en) * 1992-11-24 2000-05-02 G. D. Searle Multivariant human IL-3 fusion proteins and their recombinant production
NZ269766A (en) * 1993-07-28 1998-01-26 Medvet Science Pty Ltd Haemopoietic growth factor antagonists; relates to modified forms of such factors
AU699913B2 (en) * 1993-11-10 1998-12-17 Henry M. Jackson Foundation For The Advancement Of Military Medicine Compositions and method for stimulating antibody release by B lymphocytes
US20050059149A1 (en) * 1993-11-22 2005-03-17 Bauer S. Christopher Methods of ex-vivo expansion of hematopoeitic cells using multivariant IL-3 hematopoiesis chimera proteins
JPH10504441A (ja) 1994-03-07 1998-05-06 カイロン コーポレイション Ｔｎｆ形成阻害のための組成物およびその使用
US6465616B1 (en) 1994-04-08 2002-10-15 Bresagen Limited Interleukin-5 antagonist
US6017523A (en) * 1995-06-06 2000-01-25 G.D. Searle & Co. Therapeutic methods employing mutant human interleukin-3 (IL-3) polypeptides
WO1997012979A1 (en) * 1995-10-05 1997-04-10 G.D Searle & Co. Interleuken-3 (il-3) receptor agonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
OA09736A (en) * 1987-02-18 1993-11-30 Schering Biotech Corp "Human interleukin-3 and muteins thereof".
DE69030937T2 (de) * 1989-08-14 1997-10-09 Gist Brocades Nv Mutanten von Interleukin-3

Also Published As

Publication number Publication date
ES2133329T3 (es) 1999-09-16
DK0609280T3 (da) 1999-10-25
US5591427A (en) 1997-01-07
GR3030032T3 (en) 1999-07-30
DE69228997T2 (de) 1999-08-26
EP0609280A4 (en) 1994-09-14
EP0609280A1 (de) 1994-08-10
AU2753892A (en) 1993-05-03
CA2120707A1 (en) 1993-04-15
DE69228997D1 (de) 1999-05-27
EP0609280B1 (de) 1999-04-21
AU668364B2 (en) 1996-05-02
JPH07501520A (ja) 1995-02-16
WO1993007171A1 (en) 1993-04-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee