ATE179421T1 - Benzopyranderivate, deren herstellung und diese enthaltende pharmazeutische zusammensetzungen - Google Patents

Benzopyranderivate, deren herstellung und diese enthaltende pharmazeutische zusammensetzungen

Info

Publication number: ATE179421T1
Authority: AT; Austria
Prior art keywords: alkyl; halo; alkoxy; hydroxy; production
Prior art date: 1994-07-06

Application number

AT95401607T

Other languages

English (en)

Inventor

Gilbert Lavielle

Thierry Dubuffet

Mark Millan

Adrian Newman-Tancredi

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-07-06

Filing date

1995-07-05

Publication date

1999-05-15

1995-07-05 Application filed by Adir filed Critical Adir

1999-05-15 Application granted granted Critical

1999-05-15 Publication of ATE179421T1 publication Critical patent/ATE179421T1/de

Links

150000001562 benzopyrans Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 7
-1 pyridinecarbonyl Chemical group 0.000 abstract 7
125000003545 alkoxy group Chemical group 0.000 abstract 3
125000001475 halogen functional group Chemical group 0.000 abstract 3
YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical compound C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 2
125000004442 acylamino group Chemical group 0.000 abstract 2
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 2
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000004953 trihalomethyl group Chemical group 0.000 abstract 2
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
KYNSBQPICQTCGU-UHFFFAOYSA-N Benzopyrane Chemical compound C1=CC=C2C=CCOC2=C1 KYNSBQPICQTCGU-UHFFFAOYSA-N 0.000 abstract 1
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000006254 cycloalkyl carbonyl group Chemical group 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
125000005185 naphthylcarbonyl group Chemical group C1(=CC=CC2=CC=CC=C12)C(=O)* 0.000 abstract 1
125000005544 phthalimido group Chemical group 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000000168 pyrrolyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Addiction (AREA)
Anesthesiology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT95401607T 1994-07-06 1995-07-05 Benzopyranderivate, deren herstellung und diese enthaltende pharmazeutische zusammensetzungen ATE179421T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9408328A FR2722194B1 (fr)	1994-07-06	1994-07-06	Nouveaux derives de benzopyrane, leur procede de preparation et les compositions pharmacuetiques qui les contiennent

Publications (1)

Publication Number	Publication Date
ATE179421T1 true ATE179421T1 (de)	1999-05-15

Family

ID=9465049

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95401607T ATE179421T1 (de)	1994-07-06	1995-07-05	Benzopyranderivate, deren herstellung und diese enthaltende pharmazeutische zusammensetzungen

Country Status (16)

Country	Link
US (2)	US5663191A (de)
EP (1)	EP0691342B1 (de)
JP (1)	JP2999139B2 (de)
CN (1)	CN1049660C (de)
AT (1)	ATE179421T1 (de)
AU (1)	AU684165B2 (de)
CA (1)	CA2153195C (de)
DE (1)	DE69509308T2 (de)
DK (1)	DK0691342T3 (de)
ES (1)	ES2133686T3 (de)
FI (1)	FI111945B (de)
FR (1)	FR2722194B1 (de)
GR (1)	GR3030168T3 (de)
NO (1)	NO311085B1 (de)
NZ (1)	NZ272501A (de)
ZA (1)	ZA955631B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5891882A (en) *	1996-12-06	1999-04-06	Abbott Laboratories	Benzopyranopyrrole and benzopyranopyridine α-1 adenergic compounds
FR2764890B1 (fr) *	1997-06-24	1999-08-27	Adir	Nouveaux derives chromeniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5919802A (en) *	1997-12-05	1999-07-06	Princeton University	Methods of preventing and/or treating temporal lobe epilepsy
TWI274750B (en)	1999-01-12	2007-03-01	Abbott Gmbh & Co Kg	Triazole compounds showing high affinity to dopamine D3 receptor and pharmaceutical composition comprising the same
FR2823752B1 (fr) *	2001-04-18	2004-10-22	Servier Lab	Nouveaux derives de pyrimidin-4-ones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB0118892D0 (en) *	2001-08-02	2001-09-26	Vernalis Res Ltd	Method of treatment
US20040053968A1 (en) *	2001-12-28	2004-03-18	Hartman George D.	Methods and compositions for treating peridontal disease
EP1856126A2 (de) *	2005-02-17	2007-11-21	Wyeth a Corporation of the State of Delaware	Cycloalkyl-anelliertes indol, benzothiophen, benzofuran und inden-derivate
MX2008012566A (es) *	2006-04-03	2008-10-10	Hoffmann La Roche	Proceso para preparar acidos beta-aril o heteroaril-carboxilicos ciclicos enantiomericamente enriquecidos.
TW200924752A (en) *	2007-09-17	2009-06-16	Organon Nv	Tricyclic heterocyclic derivatives
CN102245570A (zh) *	2008-12-16	2011-11-16	弗·哈夫曼-拉罗切有限公司	制备吡咯烷-3-甲酸类的方法
FR2948372B1 (fr) *	2009-07-21	2011-07-22	Servier Lab	Nouveaux derives chromeniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN105111220A (zh) *	2015-09-12	2015-12-02	浙江大学	取代1,4-二氢苯并吡喃[2,3-b]吡咯化合物及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3518272A (en) *	1968-02-05	1970-06-30	Warner Lambert Pharmaceutical	Tetrahydro benzopyranoquinolines and process for their production
US3888946A (en) *	1971-03-17	1975-06-10	Little Inc A	Pyrano benzopyrans
AU560459B2 (en) *	1982-06-01	1987-04-09	Abbott Laboratories	Tetrahydro-benzo(e) isoindolines
US4666916A (en) *	1985-11-08	1987-05-19	Ciba-Geigy Corporation	Hexahydro-(1)-benzo-(pyrano and thiopyrano) (4,3-C)pyridines, useful as serotin-2 blocking agents
JPH03502701A (ja) *	1988-12-15	1991-06-20	アボツト・ラボラトリーズ	５‐ｈｔ選択性物質
GB8917333D0 (en) *	1989-07-28	1989-09-13	Merck Sharp & Dohme	Therapeutic agents
FR2687146B1 (fr) *	1992-02-12	1994-04-01	Adir Cie	Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

1994
- 1994-07-06 FR FR9408328A patent/FR2722194B1/fr not_active Expired - Fee Related
1995
- 1995-07-04 AU AU24826/95A patent/AU684165B2/en not_active Ceased
- 1995-07-04 CA CA002153195A patent/CA2153195C/fr not_active Expired - Fee Related
- 1995-07-05 EP EP95401607A patent/EP0691342B1/de not_active Expired - Lifetime
- 1995-07-05 US US08/498,217 patent/US5663191A/en not_active Expired - Lifetime
- 1995-07-05 NO NO19952660A patent/NO311085B1/no not_active IP Right Cessation
- 1995-07-05 AT AT95401607T patent/ATE179421T1/de active
- 1995-07-05 FI FI953308A patent/FI111945B/fi not_active IP Right Cessation
- 1995-07-05 DK DK95401607T patent/DK0691342T3/da active
- 1995-07-05 ES ES95401607T patent/ES2133686T3/es not_active Expired - Lifetime
- 1995-07-05 DE DE69509308T patent/DE69509308T2/de not_active Expired - Lifetime
- 1995-07-05 NZ NZ272501A patent/NZ272501A/en not_active IP Right Cessation
- 1995-07-05 CN CN95109942A patent/CN1049660C/zh not_active Expired - Fee Related
- 1995-07-06 JP JP7170635A patent/JP2999139B2/ja not_active Expired - Fee Related
- 1995-07-06 ZA ZA955631A patent/ZA955631B/xx unknown
1997
- 1997-01-21 US US08/786,504 patent/US5723484A/en not_active Expired - Lifetime
1999
- 1999-05-07 GR GR990401249T patent/GR3030168T3/el unknown

Also Published As

Publication number	Publication date
FI111945B (fi)	2003-10-15
DE69509308T2 (de)	1999-11-25
CN1119189A (zh)	1996-03-27
DE69509308D1 (de)	1999-06-02
CA2153195A1 (fr)	1996-01-07
NO952660L (no)	1996-01-08
FR2722194A1 (fr)	1996-01-12
FI953308A7 (fi)	1996-01-07
DK0691342T3 (da)	1999-11-08
ZA955631B (en)	1996-02-16
AU2482695A (en)	1996-01-18
EP0691342B1 (de)	1999-04-28
GR3030168T3 (en)	1999-08-31
ES2133686T3 (es)	1999-09-16
AU684165B2 (en)	1997-12-04
CA2153195C (fr)	2004-06-15
US5663191A (en)	1997-09-02
CN1049660C (zh)	2000-02-23
FI953308A0 (fi)	1995-07-05
JP2999139B2 (ja)	2000-01-17
NO952660D0 (no)	1995-07-05
NO311085B1 (no)	2001-10-08
EP0691342A1 (de)	1996-01-10
FR2722194B1 (fr)	1996-08-23
US5723484A (en)	1998-03-03
NZ272501A (en)	1996-03-26
JPH0841066A (ja)	1996-02-13

Legal Events

Date	Code	Title	Description
2000-01-15	UEP	Publication of translation of european patent specification

Publication	Publication Date	Title
ATE179421T1 (de)	1999-05-15	Benzopyranderivate, deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
BG103945A (bg)	2000-07-31	Производни на 4"-заместен-9-деоксо-9а-аза-9а- хомоеритромицин а
TR200003478T2 (tr)	2001-03-21	Antikanser maddeleri olarak faydalı izotiyazol türevleri
CY1107391T1 (el)	2010-07-28	Αρυλσυμπυκνωμενες αζαπολυκυκλικες ενωσεις
DK0539204T3 (da)	1998-09-07	Antivirale 4-substituerede-deoxy-2,3-didehydroderivater af alfa-D-neuraminsyre
HN1998000074A (es)	1999-01-08	Derivados de macrolidos c-4 sustituidos
DK0580502T3 (da)	1999-05-31	3-(hydroxybenzylidenyl)-indolin-2-oner og farmaceutiske sammensætninger indeholdende disse
TR199902995T2 (xx)	2000-02-21	9-Oksim eritromisin t�revleri
FR2619111B1 (fr)	1991-01-11	Derives de (piperidinyl-4)methyl-2 tetrahydro-1,2,3,4 9h-pyrido (3,4-b) indole, leur preparation et leur application en therapeutique
DE69920362D1 (de)	2004-10-28	Neue Makrolidderivate
UA50711C2 (uk)	2002-11-15	Антрациклінові похідні, їх застосування при лікуванні амілоїдозу та фармацевтична композиція
ITMI910456A1 (it)	1992-08-21	Composizione farmaceutica per il trattamento della cataratta
FI881609A0 (fi)	1988-04-07	Dihydropyridinamider, foerfarande foer deras framstaellning och deras anvaendning i laekemedel.
FI873892A0 (fi)	1987-09-09	Nya derivat av dihydro-oxazol, foerfarande foer deras framstaellning och deras anvaendning.
PT77666A (fr)	1983-12-01	Procede de preparation de nouveaux derives de la nitrosouree
FI810103L (fi)	1981-07-17	Nya 2,3-dihydro-imidazo /1,2-b/ pyridazinderivat foerfarande foer deras framstaellning och deras terapeutiska anvaendning
ATE170520T1 (de)	1998-09-15	Eburnan-derivate, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
ES2065192T3 (es)	1995-02-01	Nuevos nicotinatos de diacil-glicerol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
BG103985A (en)	2000-07-31	Multicyclic derivatives of erythromycin
FR2676448B1 (fr)	1995-01-20	Nouveaux derives amidiques de 1-amino octahydropyrido [2,1-c] [1,4] oxazine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
DK1202992T3 (da)	2005-01-24	Ascididemin-derivater og terapeutiske anvendelser deraf
ECSP951499A (es)	1997-04-16	Compuestos ariltios