ATE179428T1 - Verfahren zur herstellung von hepatitis antigenen und impfstoffen - Google Patents

Verfahren zur herstellung von hepatitis antigenen und impfstoffen

Info

Publication number
ATE179428T1
ATE179428T1 AT93402469T AT93402469T ATE179428T1 AT E179428 T1 ATE179428 T1 AT E179428T1 AT 93402469 T AT93402469 T AT 93402469T AT 93402469 T AT93402469 T AT 93402469T AT E179428 T1 ATE179428 T1 AT E179428T1
Authority
AT
Austria
Prior art keywords
vaccines
carried out
hepatitis antigens
producing hepatitis
purification
Prior art date
Application number
AT93402469T
Other languages
English (en)
Inventor
Bernard Fanget
Alain Francon
Original Assignee
Pasteur Merieux Serums Vacc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Merieux Serums Vacc filed Critical Pasteur Merieux Serums Vacc
Application granted granted Critical
Publication of ATE179428T1 publication Critical patent/ATE179428T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32411—Hepatovirus, i.e. hepatitis A virus
    • C12N2770/32422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32411—Hepatovirus, i.e. hepatitis A virus
    • C12N2770/32434—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT93402469T 1992-10-14 1993-10-07 Verfahren zur herstellung von hepatitis antigenen und impfstoffen ATE179428T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9212285A FR2696748B1 (fr) 1992-10-14 1992-10-14 Procédé de préparation d'antigènes et de vaccins de l'hépatite A (HAV).

Publications (1)

Publication Number Publication Date
ATE179428T1 true ATE179428T1 (de) 1999-05-15

Family

ID=9434534

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93402469T ATE179428T1 (de) 1992-10-14 1993-10-07 Verfahren zur herstellung von hepatitis antigenen und impfstoffen

Country Status (10)

Country Link
US (1) US5731187A (de)
EP (1) EP0593339B1 (de)
JP (1) JP3724821B2 (de)
AT (1) ATE179428T1 (de)
CA (1) CA2108292C (de)
DE (1) DE69324645T2 (de)
DK (1) DK0593339T3 (de)
ES (1) ES2132204T3 (de)
FR (1) FR2696748B1 (de)
GR (1) GR3030636T3 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6908598A (en) * 1996-10-29 1998-05-22 Smithkline Beecham Biologicals (Sa) Purification of respiratory syncytial virus antigens
AU5370598A (en) * 1996-12-13 1998-07-03 Schering Corporation Methods for purifying viruses
US6261823B1 (en) 1996-12-13 2001-07-17 Schering Corporation Methods for purifying viruses
US6544769B1 (en) 1996-12-13 2003-04-08 Schering Corporation Compostions comprising viruses and methods for concentrating virus preparations
DE60327069D1 (de) * 2002-04-30 2009-05-20 Oncolytics Biotech Inc Verbesserte reinigungsmethode für viren
EP1783138A4 (de) * 2004-07-27 2007-08-22 Genomidea Inc Verfahren zur aufreinigung eines virus-mantels
US7901921B2 (en) * 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
EP3121268B1 (de) * 2015-07-23 2018-12-26 Grifols, S.A. Verfahren zur reinigung eines in-vitro-hergestellten virus und clearance-assay für das virus
EP3695849A1 (de) 2019-02-13 2020-08-19 Mediagnost Gesellschaft für Forschung und Herstellung von Diagnostika GmbH Verfahren zur extraktion eines antigens des hepatitis-a-virus (hav) aus einer zellkultur
KR102277089B1 (ko) * 2019-12-19 2021-07-14 에스케이바이오사이언스(주) A형 간염 바이러스의 제조방법 및 상기의 방법에 따라 제조된 a형 간염 바이러스
JP2024004020A (ja) * 2022-06-28 2024-01-16 Ｋｍバイオロジクス株式会社 Ａ型肝炎ウイルスのクロマトグラフィー精製方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ225583A (en) * 1987-08-06 1991-07-26 Merck & Co Inc Process for purifying hepatitis a virions (hav)
JPH0761955B2 (ja) * 1988-04-28 1995-07-05 国立予防衛生研究所長 凍結乾燥ａ型肝炎ワクチン
CA2047041A1 (en) * 1990-07-18 1992-01-19 John A. Lewis Process for purification of hepatitis-a virus capsids
IT1248075B (it) * 1991-06-18 1995-01-05 Sclavo Spa Processo per la purificazione del virus dell'epatite a (hav), virus cosi` purificato e composizioni vaccinali che lo contengono.

Also Published As

Publication number Publication date
CA2108292C (en) 2005-04-12
FR2696748B1 (fr) 1994-12-30
US5731187A (en) 1998-03-24
DE69324645D1 (de) 1999-06-02
JPH06279317A (ja) 1994-10-04
DE69324645T2 (de) 1999-12-30
JP3724821B2 (ja) 2005-12-07
CA2108292A1 (en) 1994-04-15
GR3030636T3 (en) 1999-10-29
DK0593339T3 (da) 1999-11-08
ES2132204T3 (es) 1999-08-16
FR2696748A1 (fr) 1994-04-15
EP0593339A1 (de) 1994-04-20
EP0593339B1 (de) 1999-04-28

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Legal Events

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UEP Publication of translation of european patent specification