ATE179992T1 - Zusammensetzungen und methoden zur stimulation der produktion von blutplättchen mittels nicht gebundenem mpl-rezeptor - Google Patents

Zusammensetzungen und methoden zur stimulation der produktion von blutplättchen mittels nicht gebundenem mpl-rezeptor

Info

Publication number
ATE179992T1
ATE179992T1 AT95910102T AT95910102T ATE179992T1 AT E179992 T1 ATE179992 T1 AT E179992T1 AT 95910102 T AT95910102 T AT 95910102T AT 95910102 T AT95910102 T AT 95910102T AT E179992 T1 ATE179992 T1 AT E179992T1
Authority
AT
Austria
Prior art keywords
compositions
methods
mpl receptor
platelet production
stimulating platelet
Prior art date
Application number
AT95910102T
Other languages
English (en)
Inventor
Esther S Choi
Martha M Hokom
Pamela Hunt
Janet L Nichol
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE179992T1 publication Critical patent/ATE179992T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT95910102T 1994-01-21 1995-01-18 Zusammensetzungen und methoden zur stimulation der produktion von blutplättchen mittels nicht gebundenem mpl-rezeptor ATE179992T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/184,327 US5498599A (en) 1994-01-21 1994-01-21 Methods for stimulating platelet production

Publications (1)

Publication Number Publication Date
ATE179992T1 true ATE179992T1 (de) 1999-05-15

Family

ID=22676443

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95910102T ATE179992T1 (de) 1994-01-21 1995-01-18 Zusammensetzungen und methoden zur stimulation der produktion von blutplättchen mittels nicht gebundenem mpl-rezeptor

Country Status (18)

Country Link
US (1) US5498599A (de)
EP (1) EP0739354B1 (de)
JP (1) JP2853905B2 (de)
KR (1) KR100222274B1 (de)
CN (1) CN1071336C (de)
AT (1) ATE179992T1 (de)
AU (1) AU682581B2 (de)
CA (1) CA2181566C (de)
DE (1) DE69509631T2 (de)
DK (1) DK0739354T3 (de)
ES (1) ES2131308T3 (de)
GR (1) GR3030262T3 (de)
IL (1) IL112409A (de)
MX (1) MX9602905A (de)
NZ (1) NZ281395A (de)
TW (1) TW434019B (de)
WO (1) WO1995019992A1 (de)
ZA (1) ZA95526B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6589759B1 (en) 1999-03-30 2003-07-08 Trustees Of Boston University Compositions and methods for producing platelets and/or proplatelets from megakaryocytes
US6585995B1 (en) * 1999-09-21 2003-07-01 Hanson Stephen R Methods and compositions for treating platelet-related disorders
AU2001257056A1 (en) * 2000-04-14 2001-10-30 Genaissance Pharmaceuticals, Inc. Haplotypes of the mpl gene
EP1149906A1 (de) * 2000-04-25 2001-10-31 Pliva, Farmaceutska, Industrija, Dionicko Drustvo Thrombopoietin Rezeptormodulations Peptide
US20040028661A1 (en) * 2002-08-07 2004-02-12 Bartelmez Stephen H. Expansion of cells using thrombopoietin and anti-transforming growth factor-beta
ES2474573T3 (es) * 2006-01-04 2014-07-09 Baxter International Inc Medio de cultivo celular sin oligop�ptidos
US7879318B2 (en) * 2006-01-23 2011-02-01 Mcw Research Foundation, Inc. Method of reducing the effects of ischemia by administration of a thrombopoietin receptor ligand
GB201522097D0 (en) * 2015-12-15 2016-01-27 Cellular Therapeutics Ltd Cells
GB201700621D0 (en) 2017-01-13 2017-03-01 Guest Ryan Dominic Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue
BR112022011795A2 (pt) 2019-12-20 2022-08-30 Instil Bio Uk Ltd Métodos para preparar e isolar uma população terapêutica de linfócitos e para tratar câncer em um indivíduo, população terapêutica de linfócitos, bolsa criopreservada, recipiente flexível, e, sistema para extração de linfócitos
CN113502263B (zh) * 2021-06-09 2023-05-23 华南理工大学 一种促分化培养基及促进cd34阳性细胞分化为血小板的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198356A (en) * 1990-03-12 1993-03-30 Children's Hospital Medical Center Monophenotypic in vitro cell lines of megakaryocytic lineage, products produced thereby and methods
US5128449A (en) * 1988-07-05 1992-07-07 The University Of Tennessee Research Corporation Polypeptide and a method for its production
US5087448A (en) * 1989-02-02 1992-02-11 The Board Of Regents Of The University Of Oklahoma Enhancing growth of megakaryocytes in mammals using interleuking 6
US5032396A (en) * 1989-02-17 1991-07-16 Immunex Corporation IL-7 to stimulate platelet production
US5116951A (en) * 1990-09-19 1992-05-26 Ludwig Institute For Cancer Research Substantially pure interleukin-9 receptor and uses thereof
WO1992007074A1 (fr) * 1990-10-19 1992-04-30 Institut National De La Sante Et De La Recherche Medicale (Inserm) Polypeptide de la famille d'un recepteur de facteur de croissance, application au diagnostic et a la therapie des maladies myeloproliferatives
JP3811538B2 (ja) * 1996-03-28 2006-08-23 ロッテスノー株式会社 卵黄加工品およびそれを用いた冷菓
US7674220B2 (en) * 2007-08-09 2010-03-09 Illinois Tool Works Inc. Method and apparatus for applying hot-melt adhesive to zipper flanges and applying zipper to packages

Also Published As

Publication number Publication date
WO1995019992A1 (en) 1995-07-27
CN1143969A (zh) 1997-02-26
ES2131308T3 (es) 1999-07-16
HK1004485A1 (en) 1998-11-27
DE69509631T2 (de) 1999-12-30
TW434019B (en) 2001-05-16
AU682581B2 (en) 1997-10-09
KR100222274B1 (ko) 1999-10-01
DE69509631D1 (de) 1999-06-17
JP2853905B2 (ja) 1999-02-03
ZA95526B (en) 1995-12-12
JPH09502451A (ja) 1997-03-11
IL112409A (en) 1999-09-22
GR3030262T3 (en) 1999-08-31
NZ281395A (en) 1997-12-19
MX9602905A (es) 1997-06-28
AU1832495A (en) 1995-08-08
CA2181566C (en) 2000-05-30
CN1071336C (zh) 2001-09-19
DK0739354T3 (da) 1999-11-01
EP0739354A1 (de) 1996-10-30
CA2181566A1 (en) 1995-07-27
EP0739354B1 (de) 1999-05-12
IL112409A0 (en) 1995-03-30
US5498599A (en) 1996-03-12

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