ATE181672T1 - Geschmacksmaskierte feste zubereitung und verfahren zur herstellung - Google Patents
Geschmacksmaskierte feste zubereitung und verfahren zur herstellungInfo
- Publication number
- ATE181672T1 ATE181672T1 AT94106590T AT94106590T ATE181672T1 AT E181672 T1 ATE181672 T1 AT E181672T1 AT 94106590 T AT94106590 T AT 94106590T AT 94106590 T AT94106590 T AT 94106590T AT E181672 T1 ATE181672 T1 AT E181672T1
- Authority
- AT
- Austria
- Prior art keywords
- active ingredient
- preparation
- powdery
- ion exchanger
- coated
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 9
- 239000007787 solid Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 7
- 229920000642 polymer Polymers 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000003782 beta lactam antibiotic agent Substances 0.000 abstract 1
- 235000019658 bitter taste Nutrition 0.000 abstract 1
- 239000003729 cation exchange resin Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 235000019640 taste Nutrition 0.000 abstract 1
- 229920003169 water-soluble polymer Polymers 0.000 abstract 1
- 239000002132 β-lactam antibiotic Substances 0.000 abstract 1
- 229940124586 β-lactam antibiotics Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Seasonings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12509193 | 1993-04-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE181672T1 true ATE181672T1 (de) | 1999-07-15 |
Family
ID=14901627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94106590T ATE181672T1 (de) | 1993-04-28 | 1994-04-27 | Geschmacksmaskierte feste zubereitung und verfahren zur herstellung |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5464612A (de) |
| EP (1) | EP0622083B1 (de) |
| AT (1) | ATE181672T1 (de) |
| CA (1) | CA2122286A1 (de) |
| DE (1) | DE69419281T2 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824339A (en) * | 1995-09-08 | 1998-10-20 | Takeda Chemical Industries, Ltd | Effervescent composition and its production |
| ES2273409T3 (es) * | 1997-03-28 | 2007-05-01 | Eisai Co., Ltd. | Medicamento oral que previene el sabor desagradable y similar. |
| WO1998058654A1 (fr) * | 1997-06-20 | 1998-12-30 | Ohkura Pharmaceutical Co., Ltd. | Composition sous forme de gel |
| BR9705470A (pt) * | 1997-11-12 | 1999-07-06 | Ind Quimica E Farmaceutica Sch | Processo para a preparação de uma composição farmaceutica oral composição farmaceutica oral e kit compreendendo uma composição farmacêutica |
| EP1025858A4 (de) * | 1998-08-28 | 2009-03-11 | Eisai R&D Man Co Ltd | Arzneimittel mit verminderter bitterkeit usw. |
| DE60040540D1 (de) * | 1999-07-14 | 2008-11-27 | Schering Plough Ltd | Maskieren des geschmacks der oralen flüssigen chinolon-zubereitungen mit ionenaustauscherharzen |
| US6514492B1 (en) | 1999-07-14 | 2003-02-04 | Schering-Plough Veterinary Corporation | Taste masking of oral quinolone liquid preparations using ion exchange resins |
| US6451345B1 (en) * | 2000-01-20 | 2002-09-17 | Eurand Pharmaceuticals Ltd. | Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration |
| PT1260215E (pt) | 2000-03-01 | 2009-09-03 | Eisai R&D Man Co Ltd | Comprimido de desintegração rápida que contém poli(álcool vinílico) |
| CA2403594A1 (en) * | 2000-03-27 | 2002-09-18 | Kyowa Hakko Kogyo Co., Ltd. | Granules having good taking property |
| AU2001263812B2 (en) * | 2000-03-28 | 2004-09-23 | Sandoz Ag | Granulated particles with masked taste |
| US20020176842A1 (en) * | 2001-04-09 | 2002-11-28 | Lyn Hughes | Extended release of active ingredients |
| EP1429728A1 (de) * | 2001-08-29 | 2004-06-23 | SRL Technologies, Inc. | Zubereitungen mit verzögerter freisetzung |
| CZ300438B6 (cs) * | 2003-11-25 | 2009-05-20 | Pliva Hrvatska D.O.O. | Zpusob prípravy orální pevné lékové formy s okamžitým uvolnováním úcinné látky obsahující jako úcinnou látku polymorfní formu finasteridu |
| JP2005187376A (ja) * | 2003-12-25 | 2005-07-14 | Shin Etsu Chem Co Ltd | 低置換度セルロースエーテル含有カプセル及びその製造方法 |
| US20050265955A1 (en) * | 2004-05-28 | 2005-12-01 | Mallinckrodt Inc. | Sustained release preparations |
| CN102908337B (zh) | 2012-10-12 | 2014-03-05 | 大连医诺生物有限公司 | 微囊化氨基酸组合物及其制备方法 |
| CN113234206B (zh) * | 2021-04-21 | 2022-08-16 | 深圳市真味生物科技有限公司 | 一种电子烟雾化芯材料及其制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH383552A (de) * | 1958-10-24 | 1964-10-31 | Clinical Products Limited | Verfahren zur Herstellung von Harz-Arzneistoffverbindungen |
| GB856501A (en) * | 1958-11-14 | 1960-12-21 | Horner Frank W Ltd | Penicillin preparations |
| GB1462356A (en) * | 1973-07-10 | 1977-01-26 | Beecham Group Ltd | Pharmaceutical compositions |
| US3954470A (en) * | 1975-03-13 | 1976-05-04 | Gte Sylvania Incorporated | Process for fabricating a color cathode ray tube |
| US4221778A (en) * | 1979-01-08 | 1980-09-09 | Pennwalt Corporation | Prolonged release pharmaceutical preparations |
| US4762709A (en) * | 1983-09-16 | 1988-08-09 | Pennwalt Corporation | Liquid prolonged release pharmaceutical formulations containing ionic constituents |
| GB2176999B (en) * | 1985-06-22 | 1989-07-12 | Stanley Stewart Davis | Sustained release medicament |
| NZ217326A (en) * | 1985-08-26 | 1990-02-26 | Searle & Co | A porous, active drug-polymer matrix having masked taste properties, wherein the active drug contains amine or amido groups |
| US4800087A (en) * | 1986-11-24 | 1989-01-24 | Mehta Atul M | Taste-masked pharmaceutical compositions |
| US4996047A (en) * | 1988-11-02 | 1991-02-26 | Richardson-Vicks, Inc. | Sustained release drug-resin complexes |
| DE3930733A1 (de) * | 1989-09-14 | 1991-03-28 | Roehm Gmbh | Verfahren zur herstellung eines komplexierten arzneimittels |
| JPH03102284A (ja) * | 1989-09-18 | 1991-04-26 | Toshiba Glass Co Ltd | ガラス線量測定方法およびその測定装置 |
| FR2676364B1 (fr) * | 1991-05-17 | 1993-09-10 | Lafon Labor | Composition pharmaceutique a base de derives d'aminobutanone. |
-
1994
- 1994-04-27 AT AT94106590T patent/ATE181672T1/de active
- 1994-04-27 DE DE69419281T patent/DE69419281T2/de not_active Expired - Fee Related
- 1994-04-27 EP EP94106590A patent/EP0622083B1/de not_active Expired - Lifetime
- 1994-04-27 CA CA002122286A patent/CA2122286A1/en not_active Abandoned
- 1994-04-28 US US08/233,964 patent/US5464612A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69419281D1 (de) | 1999-08-05 |
| CA2122286A1 (en) | 1994-10-29 |
| DE69419281T2 (de) | 2000-03-23 |
| EP0622083A1 (de) | 1994-11-02 |
| EP0622083B1 (de) | 1999-06-30 |
| US5464612A (en) | 1995-11-07 |
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