ATE182682T1 - Verfahren und vorrichtung zur verminderung der verzerrung einer aus einer elektrophoretischen kapillare eluirenden probenzone - Google Patents

Verfahren und vorrichtung zur verminderung der verzerrung einer aus einer elektrophoretischen kapillare eluirenden probenzone

Info

Publication number
ATE182682T1
ATE182682T1 AT97945618T AT97945618T ATE182682T1 AT E182682 T1 ATE182682 T1 AT E182682T1 AT 97945618 T AT97945618 T AT 97945618T AT 97945618 T AT97945618 T AT 97945618T AT E182682 T1 ATE182682 T1 AT E182682T1
Authority
AT
Austria
Prior art keywords
sample zone
separation
capillary
eluted
separation capillaries
Prior art date
Application number
AT97945618T
Other languages
English (en)
Inventor
Eric S Nordman
Original Assignee
Perkin Elmer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perkin Elmer Corp filed Critical Perkin Elmer Corp
Application granted granted Critical
Publication of ATE182682T1 publication Critical patent/ATE182682T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Electrostatic Separation (AREA)
AT97945618T 1996-12-13 1997-11-11 Verfahren und vorrichtung zur verminderung der verzerrung einer aus einer elektrophoretischen kapillare eluirenden probenzone ATE182682T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/766,009 US5833826A (en) 1996-12-13 1996-12-13 Method and apparatus for reducing the distortion of a sample zone eluting from a capillary electrophoresis capillary

Publications (1)

Publication Number Publication Date
ATE182682T1 true ATE182682T1 (de) 1999-08-15

Family

ID=25075125

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97945618T ATE182682T1 (de) 1996-12-13 1997-11-11 Verfahren und vorrichtung zur verminderung der verzerrung einer aus einer elektrophoretischen kapillare eluirenden probenzone

Country Status (8)

Country Link
US (1) US5833826A (de)
EP (1) EP0883804B1 (de)
JP (1) JP3027198B2 (de)
AT (1) ATE182682T1 (de)
AU (1) AU708739B2 (de)
CA (1) CA2243959C (de)
DE (1) DE69700361T2 (de)
WO (1) WO1998026280A1 (de)

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US6193866B1 (en) * 1996-03-27 2001-02-27 Curagen Corporation Separation of charged particles by a spatially and temporally varying electric field
DE19725190A1 (de) * 1997-06-14 1998-12-17 Innova Gmbh Vorrichtungen mit integrierten Elektroden aus elektrisch leitfähigen Kunststoffen
AU9673198A (en) * 1997-10-02 1999-04-27 Aclara Biosciences, Inc. Capillary assays involving separation of free and bound species
FR2776072B1 (fr) 1998-03-11 2000-06-02 Centre Nat Rech Scient Perfectionnements aux dispositifs d'electrophorese multicapillaires du type a detection en sortie des capillaires
US6113767A (en) * 1998-04-24 2000-09-05 Apogee Designs, Ltd. Electrophoresis sequencing apparatus
ATE403856T1 (de) 1998-05-16 2008-08-15 Applera Corp Gerät zur überwachung der polymerase-ketten reaktion von dna
US6818437B1 (en) 1998-05-16 2004-11-16 Applera Corporation Instrument for monitoring polymerase chain reaction of DNA
US7498164B2 (en) 1998-05-16 2009-03-03 Applied Biosystems, Llc Instrument for monitoring nucleic acid sequence amplification reaction
US6024854A (en) * 1998-06-11 2000-02-15 Visible Genetics, Inc. Method and apparatus for improving electrophoresis resolution
US6270641B1 (en) 1999-04-26 2001-08-07 Sandia Corporation Method and apparatus for reducing sample dispersion in turns and junctions of microchannel systems
US6838680B2 (en) * 1999-05-12 2005-01-04 Aclara Biosciences, Inc. Multiplexed fluorescent detection in microfluidic devices
EP2383776B1 (de) * 1999-06-22 2015-02-25 President and Fellows of Harvard College Festkörper-Nanoporenvorrichtung zur Untersuchung von Biopolymeren
US6444106B1 (en) 1999-07-09 2002-09-03 Orchid Biosciences, Inc. Method of moving fluid in a microfluidic device
US20020029203A1 (en) * 2000-09-01 2002-03-07 Pelland David M. Electronic personal assistant with personality adaptation
US6994826B1 (en) 2000-09-26 2006-02-07 Sandia National Laboratories Method and apparatus for controlling cross contamination of microfluid channels
US6797139B2 (en) 2001-03-19 2004-09-28 Applera Corporation Detection cell for guiding excitation light therein and method for using same
US6596140B2 (en) 2001-05-01 2003-07-22 Applera Corporation Multi-channel capillary electrophoresis device and method
US6731437B2 (en) * 2001-05-04 2004-05-04 Applera Corporation Energy beam guide for an electrophoresis system
US20030104428A1 (en) * 2001-06-21 2003-06-05 President And Fellows Of Harvard College Method for characterization of nucleic acid molecules
JP2004537053A (ja) * 2001-07-25 2004-12-09 アプレラ コーポレイション 電気泳動検出システムにおける時間遅延積分
US7265833B2 (en) * 2001-07-25 2007-09-04 Applera Corporation Electrophoretic system with multi-notch filter and laser excitation source
US7280207B2 (en) 2001-07-25 2007-10-09 Applera Corporation Time-delay integration in a flow cytometry system
US6890409B2 (en) * 2001-08-24 2005-05-10 Applera Corporation Bubble-free and pressure-generating electrodes for electrophoretic and electroosmotic devices
US20040110205A1 (en) * 2002-09-23 2004-06-10 Hui Wang Methods and systems for nanopore data analysis
US7108775B2 (en) * 2002-11-08 2006-09-19 Applera Corporation Apparatus and method for confining eluted samples in electrophoresis systems
US6833068B2 (en) * 2003-01-13 2004-12-21 Sandia National Laboratories Passive injection control for microfluidic systems
US20040259269A1 (en) * 2003-06-20 2004-12-23 Groton Biosystems Method for detection of molecular species in a crude sample using capillary electrophoresis
US7341652B2 (en) * 2003-06-20 2008-03-11 Groton Biosytems, Llc Stationary capillary electrophoresis system
US7601545B2 (en) * 2003-06-20 2009-10-13 Groton Biosystems, Llc Automated macromolecule sample preparation system
US20040260414A1 (en) * 2003-06-20 2004-12-23 Groton Biosystems, Llc Method and apparatus for operating an automated biomolecular preparation system
US7169599B2 (en) * 2003-06-20 2007-01-30 Groton Biosystems, Llc Fluid interface for bioprocessor systems
WO2005017025A2 (en) * 2003-08-15 2005-02-24 The President And Fellows Of Harvard College Study of polymer molecules and conformations with a nanopore
US7238485B2 (en) 2004-03-23 2007-07-03 President And Fellows Of Harvard College Methods and apparatus for characterizing polynucleotides
DE102006010808B4 (de) * 2006-03-07 2009-08-13 BEGO Bremer Goldschlägerei Wilh. Herbst GmbH & Co. KG Vorrichtung, System, Verfahren, Computerprogramm und Datenträger zur elektrophoretischen Abscheidung mit einer beweglichen Elektrode
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EP0376611A3 (de) * 1988-12-30 1992-07-22 The Board Of Trustees Of The Leland Stanford Junior University Elektroforetische Vorrichtung
US5073239A (en) * 1990-01-24 1991-12-17 Bio-Rad Laboratories, Inc. Fluid introduction into a capillary by electroendosmosis
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US5439578A (en) * 1993-06-03 1995-08-08 The Governors Of The University Of Alberta Multiple capillary biochemical analyzer

Also Published As

Publication number Publication date
DE69700361D1 (de) 1999-09-02
EP0883804B1 (de) 1999-07-28
AU708739B2 (en) 1999-08-12
AU5105198A (en) 1998-07-03
DE69700361T2 (de) 2000-02-03
CA2243959C (en) 2003-03-11
EP0883804A1 (de) 1998-12-16
CA2243959A1 (en) 1998-06-18
JP3027198B2 (ja) 2000-03-27
US5833826A (en) 1998-11-10
WO1998026280A1 (en) 1998-06-18
JPH11506545A (ja) 1999-06-08

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