ATE182787T1 - Ophthalmische zusammensetzungen, die kombinationen von einem carboanhydrase-inhibitor und einem beta-adrenergischen antagonist enthalten - Google Patents

Ophthalmische zusammensetzungen, die kombinationen von einem carboanhydrase-inhibitor und einem beta-adrenergischen antagonist enthalten

Info

Publication number: ATE182787T1
Authority: AT; Austria
Prior art keywords: beta; compositions containing; adrenergic antagonist; ophthalmic compositions; containing combinations
Prior art date: 1991-04-17

Application number

AT92303330T

Other languages

English (en)

Inventor

John J Baldwin

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-04-17

Filing date

1992-04-14

Publication date

1999-08-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27103852&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE182787(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1992-04-14 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1999-08-15 Application granted granted Critical

1999-08-15 Publication of ATE182787T1 publication Critical patent/ATE182787T1/de

Links

239000002876 beta blocker Substances 0.000 title abstract 3
239000003489 carbonate dehydratase inhibitor Substances 0.000 title abstract 2
239000000203 mixture Substances 0.000 title 1
229940122072 Carbonic anhydrase inhibitor Drugs 0.000 abstract 1
206010030043 Ocular hypertension Diseases 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT92303330T 1991-04-17 1992-04-14 Ophthalmische zusammensetzungen, die kombinationen von einem carboanhydrase-inhibitor und einem beta-adrenergischen antagonist enthalten ATE182787T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US68671891A	1991-04-17	1991-04-17
US83491392A	1992-02-13	1992-02-13

Publications (1)

Publication Number	Publication Date
ATE182787T1 true ATE182787T1 (de)	1999-08-15

Family

ID=27103852

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92303330T ATE182787T1 (de)	1991-04-17	1992-04-14	Ophthalmische zusammensetzungen, die kombinationen von einem carboanhydrase-inhibitor und einem beta-adrenergischen antagonist enthalten

Country Status (24)

Country	Link
EP (1)	EP0509752B1 (de)
JP (1)	JP2527513B2 (de)
KR (1)	KR920019348A (de)
CN (1)	CN1073421C (de)
AT (1)	ATE182787T1 (de)
AU (1)	AU648659C (de)
CA (1)	CA2065965C (de)
CH (1)	CH0509752H1 (de)
CY (1)	CY2146B1 (de)
CZ (1)	CZ285129B6 (de)
DE (3)	DE69229688C5 (de)
DK (1)	DK0509752T3 (de)
ES (1)	ES2133304T3 (de)
GR (1)	GR3031467T3 (de)
IE (1)	IE921240A1 (de)
IL (1)	IL101537A (de)
LU (1)	LU90506I2 (de)
MX (1)	MX9201785A (de)
NL (1)	NL990041I2 (de)
NO (1)	NO306196B1 (de)
RO (1)	RO113612B1 (de)
SK (1)	SK282039B6 (de)
WO (1)	WO1992018124A1 (de)
YU (1)	YU39392A (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5932572A (en) *	1992-02-21	1999-08-03	Alcon Laboratories, Inc.	Topical anti-glaucoma compositions
WO1993016701A2 (en) *	1992-02-21	1993-09-02	Alcon Laboratories, Inc.	Topical antiglaucoma compositions comprising carbonic anhydrase inhibitors and beta-blockers
US6071904A (en) *	1996-12-11	2000-06-06	Alcon Laboratories, Inc.	Process for manufacturing ophthalmic suspensions
FI981473L (fi) *	1998-06-25	1999-12-26	Orion Yhtymae Oyj	Menetelmä pulmonaalihypertension hoitamiseksi
TWI298257B (en)	2001-05-31	2008-07-01	Allergan Inc	Hypotensive lipid and timolol compositions and methods of using same
CN100345594C (zh) *	2004-01-19	2007-10-31	无锡杰西医药科技有限公司	乙酰唑胺滴眼液
US8211450B2 (en) *	2010-05-05	2012-07-03	Senju Usa, Inc.	Ophthalmic composition
US9061034B2 (en)	2010-07-29	2015-06-23	Allergan, Inc.	Preservative free bimatoprost and timolol solutions
KR101820184B1 (ko)	2010-07-29	2018-01-18	알러간, 인코포레이티드	방부제가 없는 비마토프로스트 및 티몰롤 용액
JP5893204B1 (ja) *	2015-02-23	2016-03-23	参天製薬株式会社	防腐効果のある医薬の組合せ
JP6132968B1 (ja) *	2016-01-29	2017-05-24	参天製薬株式会社	ドルゾラミド、高分子およびホウ酸を含有する医薬組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4863922A (en) *	1984-12-12	1989-09-05	Merck & Co., Inc.	Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use

1992
- 1992-04-09 RO RO93-01388A patent/RO113612B1/ro unknown
- 1992-04-09 SK SK1103-93A patent/SK282039B6/sk not_active IP Right Cessation
- 1992-04-09 IL IL101537A patent/IL101537A/xx not_active IP Right Cessation
- 1992-04-09 WO PCT/US1992/002903 patent/WO1992018124A1/en not_active Ceased
- 1992-04-09 CZ CZ932098A patent/CZ285129B6/cs not_active IP Right Cessation
- 1992-04-14 DE DE69229688A patent/DE69229688C5/de not_active Expired - Lifetime
- 1992-04-14 ES ES92303330T patent/ES2133304T3/es not_active Expired - Lifetime
- 1992-04-14 EP EP92303330A patent/EP0509752B1/de not_active Expired - Lifetime
- 1992-04-14 DK DK92303330T patent/DK0509752T3/da active
- 1992-04-14 AT AT92303330T patent/ATE182787T1/de active
- 1992-04-14 DE DE2000175002 patent/DE10075002I2/de active Active
- 1992-04-14 DE DE69229688T patent/DE69229688T4/de not_active Expired - Lifetime
- 1992-04-14 CA CA002065965A patent/CA2065965C/en not_active Expired - Lifetime
- 1992-04-14 CH CH92303330T patent/CH0509752H1/fr unknown
- 1992-04-15 YU YU39392A patent/YU39392A/sh unknown
- 1992-04-15 MX MX9201785A patent/MX9201785A/es unknown
- 1992-04-16 IE IE124092A patent/IE921240A1/en not_active IP Right Cessation
- 1992-04-16 KR KR1019920006335A patent/KR920019348A/ko not_active Ceased
- 1992-04-16 CN CN92103682A patent/CN1073421C/zh not_active Expired - Lifetime
- 1992-04-16 AU AU14979/92A patent/AU648659C/en not_active Expired
- 1992-04-17 JP JP4097956A patent/JP2527513B2/ja not_active Expired - Lifetime
1993
- 1993-10-15 NO NO933714A patent/NO306196B1/no not_active IP Right Cessation
1999
- 1999-10-08 GR GR990402558T patent/GR3031467T3/el unknown
- 1999-12-01 NL NL990041C patent/NL990041I2/nl unknown
- 1999-12-29 CY CY9900045A patent/CY2146B1/xx unknown
2000
- 2000-01-19 LU LU90506C patent/LU90506I2/fr unknown

Also Published As

Publication number	Publication date
NL990041I1 (nl)	2000-02-01
CN1066781A (zh)	1992-12-09
CY2146B1 (en)	2002-06-21
SK282039B6 (sk)	2001-10-08
EP0509752A3 (en)	1993-03-03
NO306196B1 (no)	1999-10-04
DE69229688T4 (de)	2010-08-19
LU90506I2 (fr)	2000-03-28
DE69229688T2 (de)	2000-02-24
DE69229688D1 (de)	1999-09-09
RO113612B1 (ro)	1998-09-30
CZ209893A3 (en)	1994-06-15
DK0509752T3 (da)	1999-12-06
CA2065965C (en)	1998-06-16
GR3031467T3 (en)	2000-01-31
DE10075002I1 (de)	2000-03-30
DE10075002I2 (de)	2004-07-01
NO933714L (no)	1993-10-15
SK110393A3 (en)	1994-02-02
MX9201785A (es)	1992-10-01
AU648659C (en)	2008-02-14
AU1497992A (en)	1992-10-22
CZ285129B6 (cs)	1999-05-12
JPH05117167A (ja)	1993-05-14
NL990041I2 (nl)	2000-04-03
CA2065965A1 (en)	1992-10-18
IL101537A (en)	1997-11-20
WO1992018124A1 (en)	1992-10-29
JP2527513B2 (ja)	1996-08-28
DE69229688C5 (de)	2010-10-21
KR920019348A (ko)	1992-11-19
IL101537A0 (en)	1992-12-30
EP0509752A2 (de)	1992-10-21
NO933714D0 (no)	1993-10-15
ES2133304T3 (es)	1999-09-16
CN1073421C (zh)	2001-10-24
IE921240A1 (en)	1992-10-21
AU648659B2 (en)	1994-04-28
EP0509752B1 (de)	1999-08-04
YU39392A (sh)	1995-12-04
HK1009251A1 (en)	1999-05-28
CH0509752H1 (de)	2012-11-30

Publication	Publication Date	Title
ATE182787T1 (de)	1999-08-15	Ophthalmische zusammensetzungen, die kombinationen von einem carboanhydrase-inhibitor und einem beta-adrenergischen antagonist enthalten
DE59310329D1 (de)	2003-03-13	Neue Sulfonamide
EP0253094A3 (en)	1990-08-22	Use of prostaglandin d2-active substances in the treatment of ocular hypertension and glaucoma
ATE202706T1 (de)	2001-07-15	Verwendung von 9-deoxyprostaglandinderivaten zur behandlung von glaukom
FI901289A7 (fi)	1990-09-16	Muistia ja oppimista parantava tai kognitiivisten tai psykoottisten häiriöiden hoidossa käytettävä koostumus, joka sisältää D-sykloseriiniä ja D-alaniinia
DE69418947D1 (de)	1999-07-15	Stilbenderivate und analoga sowie deren anwendung
DK0445781T3 (da)	1996-02-19	Anti-glaucomapræparater indeholdende 3-arylcarbonyl-1-aminoalkyl-1H-indol
PT788361E (pt)	2002-11-29	Novas composicoes a base de uma mistura sinergetica entre pelo menos um ligante de vdr e um retinoide
FR2656214B1 (fr)	1994-07-22	Cadre dynamique d'osteosynthese du rachis.
ATE113207T1 (de)	1994-11-15	Benzamid gegen kognitive erkrankungen.
ATE150007T1 (de)	1997-03-15	Neue von amiden abgeleitete biaromatische verbinungen, pharmazeutische und kosmetische zusammensetzungen, die sie enthalten, und ihre verwendungen
ATE216889T1 (de)	2002-05-15	Anwendung von prostagrandin-analogen für die behandlung von glaukome und okuläre hypertension
IT8919968A0 (it)	1989-03-31	Procedimento e composizione per ridurre la permeabilita' diuna zona ad alta permeabilita' in un giacimento petrolifero.
IL90100A0 (en)	1989-12-15	Certain paf antagonist/antihistamine combinations and methods
ATE6590T1 (de)	1984-03-15	Verwendung von ophthalmischen zusammensetzungen, die einen plasminogenaktivator enthalten, zur reinigung von kontaktlinsen.
IT1170238B (it)	1987-06-03	Impiego di ibuprofene e flurbiprofene nella cura dell'erpete
ATE107165T1 (de)	1994-07-15	Verwendung von macrolactonen als antiallergica.
IL86752A (en)	1993-01-14	Thiophene derivatives and their preparation and their use as intermediates in the preparation of n-(2,4-dimethylthien-3-yl) -n-(1-methoxyprop-2-yl) - chloroacetamide
BE881763A (fr)	1980-08-18	Nouvelles compositions pharmaceutiques utilisables pour le traitement de l'hypertension
RU92015818A (ru)	1996-04-20	Способ для лечения энуреза
ITBO950086A0 (it)	1995-03-09	Uso di 2, 3-diidro-4(1h)-chinazolinoni e di composizioni farmaceutiche che li contengono nel trattamento dei disturbi dell'apprendimento e della memoria
IT1229511B (it)	1991-09-03	Dispositivo per la cura chirurgica dell'astigmatismo
ITFI950075V0 (it)	1995-07-26	Supporto per pallina utilizzabile per l'esercizio del coordinamento dei movimenti e/o per passatempo
ITMI910265A1 (it)	1992-08-05	Impiego di antagonisti dei recettori del trombossano nel trattamento di disfunzioni della vescica urinaria dell'uomo
IT8817908A0 (it)	1988-01-25	Macchina semiautomatica per le operazioni di raccolta,mondatura e stipatura delle drupe dell'olivo edi altri frutti simili