ATE182901T1 - Für androgen-rezeptor-protein kodierende dna - Google Patents

Für androgen-rezeptor-protein kodierende dna

Info

Publication number
ATE182901T1
ATE182901T1 AT89905317T AT89905317T ATE182901T1 AT E182901 T1 ATE182901 T1 AT E182901T1 AT 89905317 T AT89905317 T AT 89905317T AT 89905317 T AT89905317 T AT 89905317T AT E182901 T1 ATE182901 T1 AT E182901T1
Authority
AT
Austria
Prior art keywords
receptor protein
androgen receptor
dna coding
human androgen
polypeptides
Prior art date
Application number
AT89905317T
Other languages
English (en)
Inventor
Frank S French
Elisabeth M Wilson
David R Joseph
Dennis B Lubahn
Original Assignee
Univ North Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina filed Critical Univ North Carolina
Application granted granted Critical
Publication of ATE182901T1 publication Critical patent/ATE182901T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT89905317T 1988-04-15 1989-04-13 Für androgen-rezeptor-protein kodierende dna ATE182901T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/182,646 US6307030B1 (en) 1988-04-15 1988-04-15 Androgen receptor proteins, recombinant DNA molecules coding for such, and use of such compositions

Publications (1)

Publication Number Publication Date
ATE182901T1 true ATE182901T1 (de) 1999-08-15

Family

ID=22669419

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89905317T ATE182901T1 (de) 1988-04-15 1989-04-13 Für androgen-rezeptor-protein kodierende dna

Country Status (7)

Country Link
US (3) US6307030B1 (de)
EP (1) EP0365657B1 (de)
JP (1) JP3385380B2 (de)
AT (1) ATE182901T1 (de)
CA (1) CA1341347C (de)
DE (1) DE68929043T2 (de)
WO (1) WO1989009791A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614620A (en) * 1988-03-30 1997-03-25 Arch Development Corporation DNA binding proteins including androgen receptor
US6307030B1 (en) 1988-04-15 2001-10-23 The University Of North Carolina At Chapel Hill Androgen receptor proteins, recombinant DNA molecules coding for such, and use of such compositions
JPH05506141A (ja) * 1989-11-17 1993-09-16 アーチ　ディベラップメント　コーポレイション アンドロゲン受容体を含むｄｎａ結合蛋白質
CA2239976A1 (en) * 1995-09-20 1997-03-27 Paul A. Zamecnik Antisense oligonucleotide chemotherapy for benign hyperplasia or cancer of the prostate
EP0948542B1 (de) * 1996-09-11 2007-07-04 Oregon Health Sciences University Kalzium-aktivierte kaliumkanäle mit niedriger und mittlerer leitfähigkeit und ihre verwendungen.
CA2302169A1 (en) * 1998-06-30 2000-01-13 The University Of British Columbia Inhibitors of androgen-independent activation of androgen receptor
DE19834180A1 (de) 1998-07-29 2000-02-03 Benckiser Nv Zusammensetzung zur Verwendung in einer Geschirrspülmaschine
WO2002090529A1 (en) 2001-05-08 2002-11-14 Merck & Co., Inc. Dna molecules encoding macaca mulatta androgen receptor
NZ531223A (en) * 2001-07-27 2006-08-31 Univ Rochester Androgen receptor knock-out transgenic animals
AU2002318168B2 (en) 2002-02-25 2007-12-13 Vaxiion Therapeutics, Llc Minicell compositions and methods
WO2004057025A2 (en) * 2002-12-20 2004-07-08 Biodetection Systems B.V. Method for determining the presence of one or more ligands in a sample
US7467119B2 (en) * 2003-07-21 2008-12-16 Aureon Laboratories, Inc. Systems and methods for treating, diagnosing and predicting the occurrence of a medical condition
US7483554B2 (en) * 2003-11-17 2009-01-27 Aureon Laboratories, Inc. Pathological tissue mapping
US7505948B2 (en) * 2003-11-18 2009-03-17 Aureon Laboratories, Inc. Support vector regression for censored data
ATE502298T1 (de) * 2003-12-19 2011-04-15 Univ California Verfahren und materialien zur beurteilung von prostatakrebstherapien
NZ550102A (en) 2004-02-24 2010-10-29 Univ California Methods and materials for assessing prostate cancer therapies and compounds (thiohydantoine derivatives)
EP1728210A2 (de) * 2004-02-27 2006-12-06 Aureon Laboratories, Inc. Verfahren und system zur vorhersage des auftretens eines ereignisses
CA2575859A1 (en) * 2004-08-11 2006-02-23 Aureon Laboratories, Inc. Systems and methods for automated diagnosis and grading of tissue images
US7709517B2 (en) * 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
KR100777082B1 (ko) 2005-08-30 2007-11-28 주식회사 엘지생활건강 올리고뉴클레오타이드를 포함하는 피지분비 억제용 화장료조성물
SI2656842T1 (sl) 2006-03-27 2016-10-28 The Regents Of The University Of California Modulator androgenih receptorjev za zdravljenje raka prostate in bolezni, povezanih z androgenimi receptorji
WO2007127010A2 (en) 2006-03-29 2007-11-08 The Regents Of The University Of California Diarylthiohydantoin compounds
CA2654467A1 (en) * 2006-05-19 2007-11-29 University Of Rochester Prostate epithelial androgen receptor suppresses prostate growth and tumor invasion
US7910565B2 (en) * 2006-09-01 2011-03-22 Wisconsin Alumni Research Foundation Prostate cancer vaccine
WO2008116262A1 (en) * 2007-03-27 2008-10-02 Christopher Hovens Methods and compositions for treating prostate cancer
EP2620432A3 (de) 2007-10-26 2013-12-18 The Regents Of the University of California Diarylhydantoinverbindungen
CA2733506A1 (en) * 2008-08-08 2010-02-11 Christopher Hovens Biological applications of steroid binding domains
US8133724B2 (en) * 2008-09-17 2012-03-13 University Of Maryland, Baltimore Human androgen receptor alternative splice variants as biomarkers and therapeutic targets
US8841422B2 (en) 2008-09-17 2014-09-23 University Of Maryland, Baltimore Human androgen receptor alternative splice variants
GB0921873D0 (en) 2009-12-15 2010-01-27 Cytosystems Ltd Assay
AU2011218173C1 (en) 2010-02-16 2015-04-16 Aragon Pharmaceuticals, Inc. Androgen receptor modulators and uses thereof
NZ744456A (en) 2012-09-26 2019-09-27 Aragon Pharmaceuticals Inc Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
PL2945628T3 (pl) 2013-01-15 2020-09-21 Aragon Pharmaceuticals, Inc. Modulator receptorów androgenowych w skojarzeniu z octanem abirateronu i prednizonem do leczenia nowotworu stercza
WO2015168483A1 (en) * 2014-04-30 2015-11-05 Expression Pathology, Inc. Srm/mrm assay for the androgen receptor (ar) protein
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
US10702508B2 (en) 2017-10-16 2020-07-07 Aragon Pharmaceuticals, Inc. Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423208A (en) 1982-02-24 1983-12-27 Peter Grandics Affinity gel-adsorbent
JPS63502397A (ja) 1986-02-20 1988-09-14 カロビオ　エービー ステロイドレセプタ−タンパクの真核細胞における発現
WO1989009223A1 (en) 1988-03-30 1989-10-05 Arch Development Corporation Dna binding proteins including androgen receptor
US5614620A (en) * 1988-03-30 1997-03-25 Arch Development Corporation DNA binding proteins including androgen receptor
US6307030B1 (en) 1988-04-15 2001-10-23 The University Of North Carolina At Chapel Hill Androgen receptor proteins, recombinant DNA molecules coding for such, and use of such compositions

Also Published As

Publication number Publication date
DE68929043D1 (de) 1999-09-09
JPH03500605A (ja) 1991-02-14
US7129078B2 (en) 2006-10-31
US20050079576A1 (en) 2005-04-14
US6821767B1 (en) 2004-11-23
US6307030B1 (en) 2001-10-23
JP3385380B2 (ja) 2003-03-10
EP0365657A4 (en) 1991-08-21
DE68929043T2 (de) 2000-04-13
EP0365657B1 (de) 1999-08-04
WO1989009791A1 (en) 1989-10-19
CA1341347C (en) 2002-03-12
EP0365657A1 (de) 1990-05-02

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