ATE183087T1 - Verwendung von beta-hydroxy-beta- methylbutyratsäuere zur förderung der stickstoffzurückhaltung beim menschen - Google Patents

Verwendung von beta-hydroxy-beta- methylbutyratsäuere zur förderung der stickstoffzurückhaltung beim menschen

Info

Publication number
ATE183087T1
ATE183087T1 AT94903563T AT94903563T ATE183087T1 AT E183087 T1 ATE183087 T1 AT E183087T1 AT 94903563 T AT94903563 T AT 94903563T AT 94903563 T AT94903563 T AT 94903563T AT E183087 T1 ATE183087 T1 AT E183087T1
Authority
AT
Austria
Prior art keywords
beta
hydroxy
hmb
humans
nitrogen retention
Prior art date
Application number
AT94903563T
Other languages
English (en)
Inventor
Steven L Nissen
Paul J Flakkol
Naji N Abumrad
Original Assignee
Univ Iowa State Res Found Inc
Univ Vanderbilt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25542600&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE183087(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Iowa State Res Found Inc, Univ Vanderbilt filed Critical Univ Iowa State Res Found Inc
Application granted granted Critical
Publication of ATE183087T1 publication Critical patent/ATE183087T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT94903563T 1992-12-23 1993-12-09 Verwendung von beta-hydroxy-beta- methylbutyratsäuere zur förderung der stickstoffzurückhaltung beim menschen ATE183087T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/996,187 US5348979A (en) 1992-12-23 1992-12-23 Method of promoting nitrogen retention in humans

Publications (1)

Publication Number Publication Date
ATE183087T1 true ATE183087T1 (de) 1999-08-15

Family

ID=25542600

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94903563T ATE183087T1 (de) 1992-12-23 1993-12-09 Verwendung von beta-hydroxy-beta- methylbutyratsäuere zur förderung der stickstoffzurückhaltung beim menschen

Country Status (9)

Country Link
US (1) US5348979A (de)
EP (1) EP0637239B1 (de)
JP (1) JP2925326B2 (de)
AT (1) ATE183087T1 (de)
AU (1) AU664511B2 (de)
CA (1) CA2129541C (de)
DE (1) DE69325998T2 (de)
ES (1) ES2134340T3 (de)
WO (1) WO1994014429A1 (de)

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US6323237B1 (en) * 1997-03-17 2001-11-27 Btg International Limited Therapeutic compositions
US20090253781A1 (en) * 2002-05-24 2009-10-08 Btg International Limited Therapeutic compositions
US6316038B1 (en) 1997-03-17 2001-11-13 Btg International Limited Therapeutic compositions
US6103764A (en) * 1997-11-07 2000-08-15 Iowa State University Research Foundation, Inc. Method for increasing the aerobic capacity of muscle
US6031000A (en) * 1998-06-23 2000-02-29 Iowa State University Research Foundation, Inc. Composition comprising β-hydroxy-β-methylbutyric acid and at least one amino acid and methods of use
AU2620600A (en) * 1999-01-21 2000-08-07 Steroidogenesis Inhibitors International Composition of anti-hiv drugs and anti-cortisol compounds and method for decreasing the side effects of anti-hiv drugs in a human
BR0209820A (pt) * 2001-05-18 2004-06-01 Lonza Ag Processo para a preparação de formulações sólidas de 3-hidróxi-3-metilbutirato de sódio
US20040048925A1 (en) * 2002-09-09 2004-03-11 Wiley David B. Composition and method for enhancing the bioavailability of calcium and magnesium in dietary supplements and food additives
US20040106678A1 (en) * 2002-09-17 2004-06-03 Dobbins Thomas A Compositions for the parenteral administration of calcium and magnesium
US6812249B2 (en) * 2003-03-04 2004-11-02 Sal Abraham Process for preparing a 3-hydroxy-3-methylbutyrate amino acid salt and method of use
US20050215640A1 (en) 2004-03-26 2005-09-29 Baxter Jeffrey H HMB compositions and uses thereof
GB0420856D0 (en) * 2004-09-20 2004-10-20 Ketocytonyx Inc Cns modulators
EP1778213B1 (de) 2004-07-16 2017-04-05 BTG International Limited Verfahren zur herstellung oligomerer verbindungen
WO2006020179A2 (en) * 2004-07-20 2006-02-23 Ketocytonyx Inc. Oligomeric ketone compounds
WO2006012490A2 (en) * 2004-07-23 2006-02-02 Ketocytonyx Inc. Ketogenic saccharides
WO2006098767A2 (en) * 2004-09-21 2006-09-21 Ketocytonyx Inc. Treatment of adhd
US20070281892A1 (en) * 2004-09-21 2007-12-06 Martin Keith F Dopaminergic Mimetics
WO2007056176A2 (en) * 2005-11-03 2007-05-18 Southwest Immunology, Inc. Compositions for preventing and reducing delayed onset muscle soreness
JP5227182B2 (ja) 2005-12-19 2013-07-03 アボット・ラボラトリーズ １型および２型サイトカイン産生における不均衡を調節するためのベータ−ヒドロキシ−ベータ−メチルブチラートの使用
US9259430B2 (en) 2008-12-09 2016-02-16 Metabolic Technologies, Inc. Nutritional intervention for improving muscular function and strength
WO2010068696A1 (en) 2008-12-09 2010-06-17 Metabolic Technologies, Inc. Nutritional intervention for improving muscular function and strength
US9539224B2 (en) 2008-12-09 2017-01-10 Metabolic Technologies, Inc. Nutritional intervention for improving muscular function and strength
US9770424B2 (en) 2008-12-09 2017-09-26 Metabolic Technologies, Inc. Nutritional intervention for improving muscular function and strength
US11173167B2 (en) 2008-12-09 2021-11-16 Metabolic Technologies, Inc. Nutritional intervention for improving muscular function and strength
US9707241B2 (en) 2008-12-09 2017-07-18 Metabolic Technologies, Inc. Nutritional intervention for improving muscular function and strength
EP2512236B1 (de) * 2009-12-18 2016-10-19 Metabolic Technologies, Inc. Verbessertes verfahren zur verabreichung von beta-hydroxy-beta-methylbutyrat (hmb)
BR112012018174A2 (pt) 2010-01-29 2019-08-27 Abbott Lab líquidos nutricionais embalados assepticamente compreendendo hmb.
US9693577B2 (en) 2010-01-29 2017-07-04 Abbott Laboratories Method of preparing a nutritional powder comprising spray dried HMB
ES2481865T3 (es) 2010-01-29 2014-07-31 Abbott Laboratories Emulsiones nutricionales que comprenden HMB de calcio
TWI526161B (zh) * 2010-06-10 2016-03-21 亞培公司 包含鈣ｈｍｂ及可溶性蛋白質之實質上透明營養液
US10092590B2 (en) 2012-09-10 2018-10-09 Metabolic Technologies, Inc. Composition of HMB and ATP and methods of use
US20150057346A1 (en) * 2013-08-23 2015-02-26 Abbott Laboratories Methods of maintaining intramuscular myoglobin levels, maintaining maximal aerobic capacity, and enhancing the oxidative capacity of muscle in a subject
US12208073B2 (en) 2015-09-16 2025-01-28 Metabolic Technologies, LLC Compositions and methods of use of beta-hydroxy-beta-methylbutyrate (HMB) for enhancing recovery from soft tissue trauma
PT3349745T (pt) 2015-09-16 2024-03-18 Metabolic Tech Inc Composições e métodos de utilização de beta-hidroxi-beta metilbutirato (hmb) para melhorar a recuperação de traumatismos de tecidos moles
WO2017127675A1 (en) 2016-01-21 2017-07-27 Metabolic Technololgies, Inc. COMPOSITIONS AND METHODS OF USE OF β-HYDROXY-β-METHYLBUTYRATE (HMB) FOR MODULATING AUTOPHAGY AND LIPOPHAGY
HUE069527T2 (hu) 2016-10-21 2025-03-28 Metabolic Tech Llc Béta-hidroxi-béta-metil-butirát (HMB) és probiotikumok kompozíciói és alkalmazási eljárásai
JOP20190146A1 (ar) * 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
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CN112839643A (zh) 2018-06-20 2021-05-25 胺细拉健康公司 用于治疗肌肉中脂肪浸润的组合物及方法
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Also Published As

Publication number Publication date
CA2129541A1 (en) 1994-07-07
US5348979A (en) 1994-09-20
DE69325998T2 (de) 2000-01-05
DE69325998D1 (de) 1999-09-16
AU5746394A (en) 1994-07-19
CA2129541C (en) 1999-05-11
AU664511B2 (en) 1995-11-16
EP0637239A1 (de) 1995-02-08
EP0637239B1 (de) 1999-08-11
EP0637239A4 (de) 1996-12-04
JP2925326B2 (ja) 1999-07-28
JPH07507569A (ja) 1995-08-24
WO1994014429A1 (en) 1994-07-07
ES2134340T3 (es) 1999-10-01

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