ATE183312T1 - Verfahren zur reinigung und detektion von lipoprotein (a) und assoziiertem cholesterol - Google Patents
Verfahren zur reinigung und detektion von lipoprotein (a) und assoziiertem cholesterolInfo
- Publication number
- ATE183312T1 ATE183312T1 AT92913182T AT92913182T ATE183312T1 AT E183312 T1 ATE183312 T1 AT E183312T1 AT 92913182 T AT92913182 T AT 92913182T AT 92913182 T AT92913182 T AT 92913182T AT E183312 T1 ATE183312 T1 AT E183312T1
- Authority
- AT
- Austria
- Prior art keywords
- lipoprotein
- support
- purification
- detection
- bound
- Prior art date
Links
- 102000057248 Lipoprotein(a) Human genes 0.000 title abstract 5
- 108010033266 Lipoprotein(a) Proteins 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 5
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 4
- 235000012000 cholesterol Nutrition 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
- 102000004856 Lectins Human genes 0.000 abstract 2
- 108090001090 Lectins Proteins 0.000 abstract 2
- 102000004895 Lipoproteins Human genes 0.000 abstract 2
- 108090001030 Lipoproteins Proteins 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 2
- 239000002523 lectin Substances 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/60—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving cholesterol
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70445791A | 1991-05-23 | 1991-05-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE183312T1 true ATE183312T1 (de) | 1999-08-15 |
Family
ID=24829583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92913182T ATE183312T1 (de) | 1991-05-23 | 1992-05-21 | Verfahren zur reinigung und detektion von lipoprotein (a) und assoziiertem cholesterol |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5320968A (de) |
| EP (1) | EP0585387B1 (de) |
| AT (1) | ATE183312T1 (de) |
| DE (1) | DE69229784T2 (de) |
| WO (1) | WO1992021015A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5783400A (en) * | 1990-04-27 | 1998-07-21 | Genzyme Corporation | Method for the isolation of lipoprotein allowing for the subsequent quantification of its mass and cholesterol content |
| US5756067A (en) * | 1993-11-08 | 1998-05-26 | Peptide Delivery Systems Pty Ltd | Labelled diagnostic compositions and method of their use |
| US5786156A (en) * | 1993-12-21 | 1998-07-28 | Perimmune Holdings, Inc. | Immunoreactive peptides of APO(A) |
| EP0659765A3 (de) * | 1993-12-21 | 1995-09-27 | Akzo Nobel Nv | Immunorealitive Apo(a) Peptide. |
| US5994061A (en) * | 1995-09-29 | 1999-11-30 | Queen's University At Kingston | DNA constructs and methods for screening for increased expression of human apo AI gene |
| CA2246308C (en) | 1996-12-09 | 2008-11-18 | Denka Seiken Co., Ltd. | Method for quantifying cholesterol in high-density lipoprotein |
| US5814472A (en) * | 1997-05-13 | 1998-09-29 | Wako Pure Chemical Industries, Ltd. | Measurement of LDL-cholesterol |
| EP1049934A1 (de) * | 1998-01-20 | 2000-11-08 | Abbott Laboratories | Spezifische antikörper gegen kringle 5 von apolipoproteine a und verfahren zur deren verwendung |
| US6150123A (en) * | 1998-09-03 | 2000-11-21 | Centre Integre De Recherches Biocliniques Sur Le Sida (Cirbs) | Affinity biotinylation |
| ES2252358T3 (es) * | 2002-04-09 | 2006-05-16 | Cholestech Corporation | Metodo y dispositivo de ensayo para la cuantificacion del colesterol asociado a lipoproteinas de alta densidad. |
| WO2008086019A1 (en) * | 2007-01-09 | 2008-07-17 | Cholestech Corporation | Device and method for measuring ldl-associated cholesterol |
| US8247235B2 (en) | 2007-06-08 | 2012-08-21 | Quest Diagnostics Investments Incorporated | Lipoprotein analysis by differential charged-particle mobility |
| EP2645102A3 (de) * | 2007-06-08 | 2014-01-22 | Quest Diagnostics Investments Incorporated | Lipoproteinanalyse durch differentielle Mobilität für geladene Teilchen |
| US9354200B1 (en) | 2008-08-07 | 2016-05-31 | Quest Diagnostics Investments Incorporated | Detection apparatus for differential-charged particle mobility analyzer |
| US9250211B2 (en) | 2010-12-30 | 2016-02-02 | Quest Diagnostics Investments Incorporated | Magnetic separation of lipoproteins using dextran sulfate |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4126416A (en) * | 1977-11-21 | 1978-11-21 | The Trustees Of Boston University | Method for determining the level of LDL cholesterol in blood plasma |
| EP0006822B1 (de) * | 1978-07-04 | 1982-10-13 | Laboratoires Goella | Verfahren zur Bestimmung des Cholesteringehaltes im Serum und Reagens zur Durchführung des Verfahrens |
| SE448324B (sv) * | 1985-09-27 | 1987-02-09 | Pharmacia Ab | Sett vid immunkemisk bestemning av lipoproteiner och apolipoproteiner |
-
1992
- 1992-05-21 AT AT92913182T patent/ATE183312T1/de not_active IP Right Cessation
- 1992-05-21 EP EP92913182A patent/EP0585387B1/de not_active Expired - Lifetime
- 1992-05-21 WO PCT/US1992/004302 patent/WO1992021015A1/en not_active Ceased
- 1992-05-21 DE DE69229784T patent/DE69229784T2/de not_active Expired - Fee Related
-
1993
- 1993-02-23 US US08/021,189 patent/US5320968A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0585387A4 (de) | 1995-01-18 |
| US5320968A (en) | 1994-06-14 |
| EP0585387B1 (de) | 1999-08-11 |
| WO1992021015A1 (en) | 1992-11-26 |
| EP0585387A1 (de) | 1994-03-09 |
| DE69229784D1 (de) | 1999-09-16 |
| DE69229784T2 (de) | 2000-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |