ATE183742T1 - 2-aminopyrazin-5-carbonsäureamid derivate, deren herstellung und deren verwendung als heilmittel - Google Patents

2-aminopyrazin-5-carbonsäureamid derivate, deren herstellung und deren verwendung als heilmittel

Info

Publication number: ATE183742T1
Authority: AT; Austria
Prior art keywords: group; hydrogen atom; aminopyrazine; remedies; production
Prior art date: 1993-05-17

Application number

AT94401032T

Other languages

English (en)

Inventor

Pascal George

Benoit Marabout

Jacques Froissant

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-05-17

Filing date

1994-05-10

Publication date

1999-09-15

1994-05-10 Application filed by Synthelabo filed Critical Synthelabo

1999-09-15 Application granted granted Critical

1999-09-15 Publication of ATE183742T1 publication Critical patent/ATE183742T1/de

Links

-1 4-(phenoxymethyl)piperid-1-yl group Chemical group 0.000 abstract 4
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 3
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000005931 tert-butyloxycarbonyl group Chemical group [H]C([H])([H])C(OC(*)=O)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT94401032T 1993-05-17 1994-05-10 2-aminopyrazin-5-carbonsäureamid derivate, deren herstellung und deren verwendung als heilmittel ATE183742T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9305930A FR2705344B1 (fr)	1993-05-17	1993-05-17	Dérivés de 2-aminopyrazine-5-carboxamide, leur préparation et leur application en thérapeutique.

Publications (1)

Publication Number	Publication Date
ATE183742T1 true ATE183742T1 (de)	1999-09-15

Family

ID=9447217

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94401032T ATE183742T1 (de)	1993-05-17	1994-05-10	2-aminopyrazin-5-carbonsäureamid derivate, deren herstellung und deren verwendung als heilmittel

Country Status (19)

Country	Link
US (1)	US5420130A (de)
EP (1)	EP0625514B1 (de)
JP (1)	JPH06329645A (de)
CN (1)	CN1104637A (de)
AT (1)	ATE183742T1 (de)
AU (1)	AU671361B2 (de)
CA (1)	CA2123668A1 (de)
CZ (1)	CZ283499B6 (de)
DE (1)	DE69420179D1 (de)
FI (1)	FI942265L (de)
FR (1)	FR2705344B1 (de)
HU (1)	HUT69711A (de)
IL (1)	IL109655A (de)
NO (1)	NO941830L (de)
NZ (1)	NZ260531A (de)
PL (1)	PL173309B1 (de)
RU (1)	RU2128176C1 (de)
SK (1)	SK57494A3 (de)
ZA (1)	ZA943353B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MXPA00010805A (es) *	1998-05-06	2002-05-08	Univ Duke	Metodo para el tratamiento de sindromes de la vejiga y del tracto urinario inferior.
PL200955B1 (pl)	1998-08-20	2009-02-27	Toyama Chemical Co Ltd	Przeciwwirusowa kompozycja farmaceutyczna i jej zastosowanie oraz zawierająca azot heterocykliczna pochodna karboksamidu

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4041032A (en) *	1974-01-16	1977-08-09	Yamanouchi Pharmaceutical Co., Ltd.	Pyrazine derivatives
GB8712365D0 (en) *	1987-05-26	1987-07-01	Ici America Inc	Aminomethylphenolic pyrazines
FR2656609B1 (fr) *	1989-12-28	1992-03-27	Synthelabo	Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.

1993
- 1993-05-17 FR FR9305930A patent/FR2705344B1/fr not_active Expired - Fee Related
1994
- 1994-05-10 DE DE69420179T patent/DE69420179D1/de not_active Expired - Lifetime
- 1994-05-10 EP EP94401032A patent/EP0625514B1/de not_active Expired - Lifetime
- 1994-05-10 AT AT94401032T patent/ATE183742T1/de not_active IP Right Cessation
- 1994-05-15 IL IL10965594A patent/IL109655A/en not_active IP Right Cessation
- 1994-05-16 RU RU94016363A patent/RU2128176C1/ru active
- 1994-05-16 PL PL94303478A patent/PL173309B1/pl unknown
- 1994-05-16 US US08/243,315 patent/US5420130A/en not_active Expired - Fee Related
- 1994-05-16 AU AU63126/94A patent/AU671361B2/en not_active Ceased
- 1994-05-16 CZ CZ941195A patent/CZ283499B6/cs unknown
- 1994-05-16 CA CA002123668A patent/CA2123668A1/en not_active Abandoned
- 1994-05-16 ZA ZA943353A patent/ZA943353B/xx unknown
- 1994-05-16 CN CN94105541A patent/CN1104637A/zh active Pending
- 1994-05-16 SK SK574-94A patent/SK57494A3/sk unknown
- 1994-05-16 NZ NZ260531A patent/NZ260531A/en unknown
- 1994-05-16 NO NO941830A patent/NO941830L/no unknown
- 1994-05-16 JP JP6100999A patent/JPH06329645A/ja active Pending
- 1994-05-16 FI FI942265A patent/FI942265L/fi unknown
- 1994-05-16 HU HU9401512A patent/HUT69711A/hu unknown

Also Published As

Publication number	Publication date
DE69420179D1 (de)	1999-09-30
RU2128176C1 (ru)	1999-03-27
NO941830D0 (no)	1994-05-16
FI942265A7 (fi)	1994-11-18
FR2705344A1 (fr)	1994-11-25
IL109655A0 (en)	1994-08-26
FI942265L (fi)	1994-11-18
CZ283499B6 (cs)	1998-04-15
CN1104637A (zh)	1995-07-05
CA2123668A1 (en)	1994-11-18
IL109655A (en)	1999-03-12
CZ119594A3 (en)	1994-12-15
EP0625514B1 (de)	1999-08-25
HUT69711A (en)	1995-09-28
JPH06329645A (ja)	1994-11-29
US5420130A (en)	1995-05-30
AU671361B2 (en)	1996-08-22
ZA943353B (en)	1995-03-28
NZ260531A (en)	1995-10-26
RU94016363A (ru)	1996-04-10
HU9401512D0 (en)	1994-08-29
AU6312694A (en)	1994-11-24
PL173309B1 (pl)	1998-02-27
EP0625514A1 (de)	1994-11-23
FI942265A0 (fi)	1994-05-16
NO941830L (no)	1994-11-18
SK57494A3 (en)	1995-07-11
FR2705344B1 (fr)	1995-06-30

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Legal Events

Date	Code	Title	Description
2000-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties