ATE183774T1 - Löslicher interferon-rezeptor, seine herstellung und anwendung - Google Patents

Löslicher interferon-rezeptor, seine herstellung und anwendung

Info

Publication number: ATE183774T1
Authority: AT; Austria
Prior art keywords: preparation; application; interferon receptor; soluble interferon; soluble
Prior art date: 1993-10-24

Application number

AT94116559T

Other languages

English (en)

Inventor

Carolina Abramovich

Edward Ratovitski

Michel Revel

Original Assignee

Yeda Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-10-24

Filing date

1994-10-20

Publication date

1999-09-15

1994-10-20 Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev

1999-09-15 Application granted granted Critical

1999-09-15 Publication of ATE183774T1 publication Critical patent/ATE183774T1/de

Links

102000001617 Interferon Receptors Human genes 0.000 title 1
108010054267 Interferon Receptors Proteins 0.000 title 1
102000007438 Interferon alpha-beta Receptor Human genes 0.000 abstract 1
108010086140 Interferon alpha-beta Receptor Proteins 0.000 abstract 1
238000003745 diagnosis Methods 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6866—Interferon
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Cell Biology (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
General Physics & Mathematics (AREA)
Zoology (AREA)
Toxicology (AREA)
Biotechnology (AREA)
Oncology (AREA)
Microbiology (AREA)
Pathology (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Genetics & Genomics (AREA)
Neurology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Neurosurgery (AREA)

AT94116559T 1993-10-24 1994-10-20 Löslicher interferon-rezeptor, seine herstellung und anwendung ATE183774T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IL10737893A IL107378A (en)	1993-10-24	1993-10-24	SOLUBLE INTERFERON alpha-RECEPTOR, ITS PREPARATION AND USE

Publications (1)

Publication Number	Publication Date
ATE183774T1 true ATE183774T1 (de)	1999-09-15

Family

ID=11065371

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94116559T ATE183774T1 (de)	1993-10-24	1994-10-20	Löslicher interferon-rezeptor, seine herstellung und anwendung

Country Status (13)

Country	Link
US (1)	US5643749A (de)
EP (1)	EP0679717B1 (de)
JP (3)	JPH07236488A (de)
AT (1)	ATE183774T1 (de)
AU (1)	AU684103B2 (de)
CA (1)	CA2134030C (de)
DE (1)	DE69420251T2 (de)
DK (1)	DK0679717T3 (de)
ES (1)	ES2140489T3 (de)
GR (1)	GR3031354T3 (de)
IL (1)	IL107378A (de)
SI (1)	SI0679717T1 (de)
ZA (1)	ZA948345B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE181961T1 (de) *	1991-04-17	1999-07-15	Medisup Int Nv	Neue wasserlösliche polypeptide mit hoher affinität für alpha- und beta- interferone
US5780027A (en) *	1995-07-14	1998-07-14	Meiogen Biotechnology Corporation	Methods of treatment of down syndrome by interferon antagonists
US7063958B1 (en) *	1996-01-16	2006-06-20	The Rockefeller University	Nucleic acids db, the receptor for leptin
EP1021726B1 (de) *	1996-08-19	2004-12-15	Shaker, Ghassan I.	Verwendung von molt4 cd69 expression zur bestimmung der anwesenheit und der aktivität von interferoninhibitoren
EP1780277A1 (de) *	1997-01-15	2007-05-02	Yeda Research And Development Company, Ltd.	IFN Rezeptor 1 bindende Proteine, dafür kodierende DNA und Verfahren zur Regulierung der zellulären Antwort auf Interferone
KR100799828B1 (ko) *	1997-01-15	2008-01-31	예다 리서치 앤드 디벨럽먼트 캄파니 리미티드	신규한 인터페론 수용체 1 결합 단백질들, 이들을 코딩하는 디엔에이 및 인터페론에 대한 세포성 반응을 조절하는 방법
US20020119129A1 (en)	1997-01-15	2002-08-29	Yeda Research And Development Co. Ltd.	Novel IFN receptor 1 binding proteins, DNA encoding them, and methods of modulating cellular response to interferons
NZ504771A (en) *	1997-12-19	2002-09-27	Applied Research Systems	IFNAR2/ INFcomplex for prolonging the in vivo effects of type I interferon (INF)
AUPP670698A0 (en) *	1998-10-23	1998-11-19	Monash University	A method of regulation
UA74557C2 (en)	1999-09-03	2006-01-16	Applied Research Systems	A method for producing a heterologous secreted protein from chinese hamster ovaries cells grown on microcarriers
IL147414A0 (en) *	2001-12-31	2002-08-14	Yeda Res & Dev	Ifnar2 mutants, their production and use
AU2006262289A1 (en) *	2005-06-22	2007-01-04	Genentech, Inc.	Methods and compositions for targeting IFNAR2
RU2411039C2 (ru) *	2007-12-26	2011-02-10	Валентина Васильевна Малиновская	Иммунокорригирующее средство для лечения заболеваний вирусной этиологии
WO2013003475A1 (en)	2011-06-27	2013-01-03	Cellscript, Inc.	Inhibition of innate immune response
ES2470816B1 (es) *	2012-11-22	2015-04-01	Servicio Andaluz De Salud	Proteína recombinante y usos en el diagnóstico de la esclerosis múltiple
CA3029627A1 (en)	2016-07-01	2018-01-04	Resolve Therapeutics, Llc	Optimized binuclease fusions and methods
BR112020003670A2 (pt)	2017-08-22	2020-09-01	Sanabio, Llc	receptores de interferon solúveis e usos dos mesmos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE132191T1 (de) *	1989-04-19	1996-01-15	Hoffmann La Roche	Auflösbare interferon-gamma-rezeptoren sowie verfahren zu deren herstellung
IL91562A0 (en) *	1989-09-07	1990-04-29	Yeda Res & Dev	Interferon-gamma receptor fragment and its production
ATE181961T1 (de) *	1991-04-17	1999-07-15	Medisup Int Nv	Neue wasserlösliche polypeptide mit hoher affinität für alpha- und beta- interferone
IL106591A (en) *	1992-09-03	2008-03-20	Yeda Res & Dev	Interferon alpha/beta binding protein, its preparation and pharmaceutical compositions containing it

1993
- 1993-10-24 IL IL10737893A patent/IL107378A/xx not_active IP Right Cessation
1994
- 1994-10-20 DK DK94116559T patent/DK0679717T3/da active
- 1994-10-20 DE DE69420251T patent/DE69420251T2/de not_active Expired - Lifetime
- 1994-10-20 AT AT94116559T patent/ATE183774T1/de active
- 1994-10-20 ES ES94116559T patent/ES2140489T3/es not_active Expired - Lifetime
- 1994-10-20 EP EP94116559A patent/EP0679717B1/de not_active Expired - Lifetime
- 1994-10-20 AU AU75977/94A patent/AU684103B2/en not_active Expired
- 1994-10-20 SI SI9430275T patent/SI0679717T1/xx unknown
- 1994-10-21 CA CA2134030A patent/CA2134030C/en not_active Expired - Lifetime
- 1994-10-24 ZA ZA948345A patent/ZA948345B/xx unknown
- 1994-10-24 JP JP6284046A patent/JPH07236488A/ja not_active Withdrawn
- 1994-10-24 US US08/328,256 patent/US5643749A/en not_active Expired - Lifetime
1999
- 1999-09-29 GR GR990402447T patent/GR3031354T3/el unknown
2004
- 2004-12-07 JP JP2004354550A patent/JP2005130865A/ja active Pending
2006
- 2006-11-10 JP JP2006305759A patent/JP2007097593A/ja active Pending

Also Published As

Publication number	Publication date
CA2134030A1 (en)	1995-04-25
ZA948345B (en)	1995-07-17
DE69420251T2 (de)	2000-05-11
AU7597794A (en)	1995-05-11
JPH07236488A (ja)	1995-09-12
DE69420251D1 (de)	1999-09-30
CA2134030C (en)	2010-06-29
JP2007097593A (ja)	2007-04-19
IL107378A0 (en)	1994-01-25
US5643749A (en)	1997-07-01
EP0679717A3 (de)	1997-04-23
EP0679717B1 (de)	1999-08-25
ES2140489T3 (es)	2000-03-01
JP2005130865A (ja)	2005-05-26
GR3031354T3 (en)	2000-01-31
SI0679717T1 (en)	1999-12-31
EP0679717A2 (de)	1995-11-02
DK0679717T3 (da)	2000-03-13
IL107378A (en)	2005-05-17
AU684103B2 (en)	1997-12-04

Legal Events

Date	Code	Title	Description
2000-03-15	UEP	Publication of translation of european patent specification

Publication	Publication Date	Title
ATE183774T1 (de)	1999-09-15	Löslicher interferon-rezeptor, seine herstellung und anwendung
DE10199018I1 (de)	2001-07-12	Thiazolidindion-Derivate deren Herstellung und Anwendung
ATE224910T1 (de)	2002-10-15	Derivate von dolestatin, deren herstellung und verwendung
ATE211467T1 (de)	2002-01-15	4-amino-derivate der mycophenolsäure mit immun suppressiver wirkung
EE9800459A (et)	1999-06-15	Spiro-piperidiini derivaadid ja nende kasutamine terapeutiliste toimeainetena
FI950458A7 (fi)	1995-08-04	N-(3-aminopropyyli)-N-fenyyli-5,6,7,8-tetrahydronaftalen-2-karboksamidijohdannaiset, niiden valmistus ja terapeuttinen käyttö
DE68913739D1 (de)	1994-04-14	Kosmetische und hautbehandlungs-zusammensetzungen.
ATE218567T1 (de)	2002-06-15	1h-pyrido(3,4-b)indolcarboxamidderivate, ihre herstellung und therapeutische verwendung
DE3779250D1 (de)	1992-06-25	Acrylcopolymere, diese enthaltende hautschutzmittel und ihre anwendung.
ATE226584T1 (de)	2002-11-15	4-oxo-3,5-dihydro-4h-pyridazino(4,5-b)indol-1- acetamid-derivate, ihre herstellung und therapeutische anwendung
FI941068A7 (fi)	1994-09-09	Bentsoksatsiinijohdannaiset, niiden valmistus ja terapeuttinen käyttö
FI892344A7 (fi)	1989-11-18	6-fenyyli-3-piperatsinyylialkyyli-1H,3H-pyrimidiini-2,4-dionin johdannaisia, niiden valmistus ja niiden terapeuttinen käyttö
DE69330075D1 (de)	2001-05-10	Oxazolinderivate, ihre Herstellung und Anwendung
DE59100496D1 (de)	1993-11-25	Verwendung von selektiv hydrierten Styrol-Butadien-Copolymerisaten in kosmetischen und pharmazeutischen Zubereitungen.
ATE184005T1 (de)	1999-09-15	Oxazolidinone derivate, ihre herstellung und ihre therapeutische verwendung
DE69408211D1 (de)	1998-03-05	Polyfunktionelle Polyisobutylene, ihre Herstellung, ihre Formulierung und ihre Anwendung
DE69217783D1 (de)	1997-04-10	3-Phenoxybenzyl(iden)pyrrolidin-Derivate, deren Herstellung und deren Verwendung als muskarin-cholinerge Mittel
EE03687B1 (et)	2002-04-15	Furaandiarüülmetülideeni derivaadid, nende valmistamise meetod ja kasutamine teraapias
EE9900135A (et)	1999-12-15	N-(2-bensotiasolüül)-1-piperidiinetaanamiini derivaadid, nende valmistamine ja kasutamine raviks
ATE198192T1 (de)	2001-01-15	Benzolsulfonamidderivate, ihre herstellung und ihre therapeutische verwendung
ATE210126T1 (de)	2001-12-15	4-amino-6-substituierte mycophenolsäurederivate mit immunsuppressiver wirkung
ATE205841T1 (de)	2001-10-15	Derivate von 5-naphthalin-1-yl-1,3-dioxanen, ihre herstellung und therapeutische anwendung
DE3788888D1 (de)	1994-03-10	Perhydrothiazepin- und Perhydroazepinderivate, ihre Herstellung und ihre therapeutische Verwendung.
FR2753196B1 (fr)	1998-10-23	Derives d'indazole tricyclique, leur preparation et leur application en therapeutique
DE69015602D1 (de)	1995-02-09	Oxadiazolinon-Derivat, seine Herstellung und seine Verwendung.