ATE185816T1 - In sol-gel immobilizierte lipase bearbeitet hydrophoben substanzen - Google Patents

In sol-gel immobilizierte lipase bearbeitet hydrophoben substanzen

Info

Publication number
ATE185816T1
ATE185816T1 AT95103126T AT95103126T ATE185816T1 AT E185816 T1 ATE185816 T1 AT E185816T1 AT 95103126 T AT95103126 T AT 95103126T AT 95103126 T AT95103126 T AT 95103126T AT E185816 T1 ATE185816 T1 AT E185816T1
Authority
AT
Austria
Prior art keywords
sol
hydrophobic substances
gel processes
lipase immobilized
processes hydrophobic
Prior art date
Application number
AT95103126T
Other languages
English (en)
Inventor
Manfred T Reetz
Joerg Simpelkamp
Albin Zonta
Original Assignee
Studiengesellschaft Kohle Mbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Studiengesellschaft Kohle Mbh filed Critical Studiengesellschaft Kohle Mbh
Application granted granted Critical
Publication of ATE185816T1 publication Critical patent/ATE185816T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/02—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils
    • C11C1/04—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by hydrolysis
    • C11C1/045—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by hydrolysis using enzymes or microorganisms, living or dead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/003—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with alcohols
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/04—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils
    • C11C3/08—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils with fatty acids
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/04—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils
    • C11C3/10—Ester interchange
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/084—Polymers containing vinyl alcohol units
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Silicon Polymers (AREA)
  • Colloid Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fats And Perfumes (AREA)
AT95103126T 1994-03-11 1995-03-04 In sol-gel immobilizierte lipase bearbeitet hydrophoben substanzen ATE185816T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4408152A DE4408152A1 (de) 1994-03-11 1994-03-11 Immobilisierte Lipasen in hydrophoben Sol-Gel-Materialien

Publications (1)

Publication Number Publication Date
ATE185816T1 true ATE185816T1 (de) 1999-11-15

Family

ID=6512449

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95103126T ATE185816T1 (de) 1994-03-11 1995-03-04 In sol-gel immobilizierte lipase bearbeitet hydrophoben substanzen

Country Status (8)

Country Link
US (2) US5817493A (de)
EP (1) EP0676414B1 (de)
JP (1) JPH07274964A (de)
AT (1) ATE185816T1 (de)
CA (1) CA2144218A1 (de)
DE (2) DE4408152A1 (de)
DK (1) DK0676414T3 (de)
ES (1) ES2137388T3 (de)

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US6140475A (en) * 1997-04-11 2000-10-31 Altus Biologics Inc. Controlled dissolution crosslinked protein crystals
DE19731990A1 (de) * 1997-07-25 1999-01-28 Studiengesellschaft Kohle Mbh Verfahren zur Herstellung und Identifizierung von neuen Hydrolasen mit verbesserten Eigenschaften
US6756217B1 (en) * 1998-05-29 2004-06-29 Southern Illinois University Glass composite materials containing alkoxosilane derivative having alterable charge, hydrophobic and hydrophilic groups
DE19850507C1 (de) * 1998-11-03 2000-05-04 Goldschmidt Ag Th Verfahren zur Herstellung von Acrylsäureestern und/oder Methacrylsäureestern von hydroxyfunktionellen Siloxanen und/oder polyoxyalkylenmodifizierten Siloxanen und deren Verwendung
FR2788280B1 (fr) * 1999-01-08 2001-04-06 Sophim Procede de fabrication d'un emollient non gras a partir d'extraits d'olives
US20010046493A1 (en) * 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
DE10041809A1 (de) * 2000-08-25 2002-03-07 Giesing Michael Arrays immobilisierter Biomoleküle, deren Herstellung und Verwendung
DE10046039A1 (de) * 2000-09-18 2002-03-28 Basf Ag Polykondensation von organischen Siliciumverbindungen
US6790275B2 (en) 2001-09-25 2004-09-14 W. R. Grace & Co.-Conn. Pumpably verifiable fluid fiber compositions
US6569233B2 (en) 2001-09-25 2003-05-27 W. R. Grace & Co.-Conn. Pumpably verifiable fluid fiber compositions
US20030153026A1 (en) * 2002-01-04 2003-08-14 Javier Alarcon Entrapped binding protein as biosensors
US6855556B2 (en) 2002-01-04 2005-02-15 Becton, Dickinson And Company Binding protein as biosensors
US20030207304A1 (en) * 2002-04-26 2003-11-06 Eric Black Glycerol-doped aerogel coatings as biological capture media
AU2003229206A1 (en) * 2002-05-31 2003-12-19 Mcmaster University Polyol-modified silanes as precursors for silica
CA2496736C (en) * 2002-08-23 2012-11-13 Mcmaster University Methods and compounds for controlling the morphology and shrinkage of silica derived from polyol-modified silanes
US7311926B2 (en) * 2002-12-20 2007-12-25 Battelle Memorial Institute Biocomposite materials and methods for making the same
US7142464B2 (en) * 2003-04-29 2006-11-28 Saifun Semiconductors Ltd. Apparatus and methods for multi-level sensing in a memory array
US7642077B2 (en) 2003-12-08 2010-01-05 Genencor International, Inc. Biocomposite comprising co-precipitate of enzyme, silicate and polyamine
WO2005124348A1 (en) * 2004-06-09 2005-12-29 Becton, Dickinson And Company Multianalyte sensor
DK1809320T3 (da) * 2004-10-14 2010-11-15 Cystic Fibrosis Foundation The Præparater indeholdende lipase, protease og amylase til behandling af pankreatisk insufficiens
FR2877007B1 (fr) * 2004-10-22 2006-12-08 Rhodia Chimie Sa Preparation de silicones et silanes fonctionnalises via une catalyse enzymatique
KR20140053410A (ko) 2005-08-19 2014-05-07 아보트 러보러터리즈 이원 가변 도메인 면역글로불린 및 이의 용도
US20100196344A1 (en) * 2005-10-14 2010-08-05 Cystic Fibrosis Foundation Therapeutics, Inc. Compositions and methods for treating pancreatic insufficiency
IL180598A0 (en) * 2007-01-08 2007-07-04 Basheer Sobhi Immobilized interfacial enzymes of improved and stabilized activity
ITMI20070435A1 (it) 2007-03-05 2008-09-06 Innovate Biotechnology Srl 2',3'-di-o-acil-5-fluoronucleosidi
DE102010028788B4 (de) * 2010-05-10 2022-03-31 Tutech Innovation Gmbh Ein in der Reaktivrektifikation einsetzbarer, einen Biokatalysator aufweisender Kolonneneinbau und dessen Verwendung in der Reaktivrektifikation
CA2869568A1 (en) * 2012-04-06 2013-10-10 Akermin, Inc. Polysilicate-polysilicone enzyme immobilization materials
WO2014071389A1 (en) 2012-11-05 2014-05-08 Veech Richard L Ketone bodies to protect tissues from damage by ionizing radiation
GB2552704A (en) * 2016-08-04 2018-02-07 Univ Bath Biomolecule preservation
CN114836409A (zh) * 2022-05-05 2022-08-02 南京师范大学 生物分子的固定化方法及其应用
CN118663226B (zh) * 2024-07-09 2025-05-16 内蒙古北峰岭粮油有限公司 一种凹凸棒复合酶脱色剂的制备方法和应用

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FR2267992A1 (de) * 1974-04-19 1975-11-14 Rhone Poulenc Ind
US4148689A (en) * 1976-05-14 1979-04-10 Sanraku-Ocean Co., Ltd. Immobilization of microorganisms in a hydrophilic complex gel
DE3537259A1 (de) * 1985-10-19 1987-04-23 Hoechst Ag Copolymerisat, verfahren zu seiner herstellung und seine verwendung als enzymtraeger
SU1696475A1 (ru) * 1989-02-09 1991-12-07 Институт Микробиологии Ан Узсср Способ получени иммобилизованной липазы
WO1990012092A1 (de) * 1989-04-04 1990-10-18 Fritz Pittner Verfahren zum immobilisieren von proteinen, peptiden, coenzymen od.dgl. an einem träger
US5200334A (en) * 1991-08-13 1993-04-06 The Regents Of The University Of California Sol-gel encapsulated enzyme
JP3030245B2 (ja) * 1995-12-26 2000-04-10 三洋電機株式会社 画像表示装置

Also Published As

Publication number Publication date
US6080402A (en) 2000-06-27
ES2137388T3 (es) 1999-12-16
EP0676414A1 (de) 1995-10-11
DK0676414T3 (da) 2000-04-25
JPH07274964A (ja) 1995-10-24
DE4408152A1 (de) 1995-09-14
US5817493A (en) 1998-10-06
DE69512817T2 (de) 2000-04-06
DE69512817D1 (de) 1999-11-25
EP0676414B1 (de) 1999-10-20
CA2144218A1 (en) 1995-09-12

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee