ATE186734T1 - L-lysyl-glycyl-l-histidin und entsprechende pharmazeutische zusammensetzungen zur wundheilung - Google Patents

L-lysyl-glycyl-l-histidin und entsprechende pharmazeutische zusammensetzungen zur wundheilung

Info

Publication number: ATE186734T1
Authority: AT; Austria
Prior art keywords: glycyl; lysyl; histidine; wound healing; pharmaceutical compositions
Prior art date: 1994-05-27

Application number

AT95107298T

Other languages

English (en)

Inventor

Masayoshi Koyama

Mikiko Takahashi

Masayoshi Yanagawa

Original Assignee

Hoechst Japan

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-05-27

Filing date

1995-05-13

Publication date

1999-12-15

1995-05-13 Application filed by Hoechst Japan filed Critical Hoechst Japan

1999-12-15 Application granted granted Critical

1999-12-15 Publication of ATE186734T1 publication Critical patent/ATE186734T1/de

Links

UETQMSASAVBGJY-QWRGUYRKSA-N Lys-Gly-His Chemical compound NCCCC[C@H](N)C(=O)NCC(=O)N[C@H](C(O)=O)CC1=CNC=N1 UETQMSASAVBGJY-QWRGUYRKSA-N 0.000 title abstract 4
239000008194 pharmaceutical composition Substances 0.000 title 1
230000029663 wound healing Effects 0.000 title 1
JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 abstract 1
210000002950 fibroblast Anatomy 0.000 abstract 1
239000002184 metal Chemical class 0.000 abstract 1
229910052751 metal Chemical class 0.000 abstract 1
230000035755 proliferation Effects 0.000 abstract 1
230000001737 promoting effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000003357 wound healing promoting agent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT95107298T 1994-05-27 1995-05-13 L-lysyl-glycyl-l-histidin und entsprechende pharmazeutische zusammensetzungen zur wundheilung ATE186734T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP6115161A JPH07316192A (ja)	1994-05-27	1994-05-27	Ｌ−リシル−グリシル−ｌ−ヒスチジンおよびこれを含有する創傷治療剤

Publications (1)

Publication Number	Publication Date
ATE186734T1 true ATE186734T1 (de)	1999-12-15

Family

ID=14655848

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95107298T ATE186734T1 (de)	1994-05-27	1995-05-13	L-lysyl-glycyl-l-histidin und entsprechende pharmazeutische zusammensetzungen zur wundheilung

Country Status (11)

Country	Link
US (1)	US5591711A (de)
EP (1)	EP0684259B1 (de)
JP (1)	JPH07316192A (de)
KR (1)	KR950032272A (de)
AT (1)	ATE186734T1 (de)
AU (1)	AU705569B2 (de)
CA (1)	CA2150334A1 (de)
DE (1)	DE69513324T2 (de)
DK (1)	DK0684259T3 (de)
ES (1)	ES2140575T3 (de)
GR (1)	GR3032077T3 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6515009B1 (en)	1991-09-27	2003-02-04	Neorx Corporation	Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en)	1993-01-28	1998-09-22	Neorx Corporation	Therapeutic inhibitor of vascular smooth muscle cells
US6491938B2 (en)	1993-05-13	2002-12-10	Neorx Corporation	Therapeutic inhibitor of vascular smooth muscle cells
GB2321191B (en) *	1997-01-17	2000-09-27	Johnson & Johnson Medical	Peptides for use in wound treatment
US6117911A (en)	1997-04-11	2000-09-12	Neorx Corporation	Compounds and therapies for the prevention of vascular and non-vascular pathologies
US20030130185A1 (en) *	2000-09-29	2003-07-10	David Bar-Or	Metal-binding compounds and uses therefor
US7632803B2 (en)	1999-10-01	2009-12-15	Dmi Life Sciences, Inc.	Metal-binding compounds and uses therefor
US20030158111A1 (en) *	1999-10-01	2003-08-21	David Bar-Or	Methods and products for oral care
CN1390231A (zh)	1999-10-01	2003-01-08	Dmi生物科学公司	金属－结合性化合物及其用途
US7592304B2 (en)	1999-10-01	2009-09-22	Dmi Life Sciences, Inc.	Metal-binding compounds and uses therefor
US6613083B2 (en)	2001-05-02	2003-09-02	Eckhard Alt	Stent device and method
US20210369768A1 (en) *	2020-06-01	2021-12-02	Balchem Corporation	Metal di-amino acid chelates or metal tri-amino acid chelates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4760051A (en) *	1985-01-24	1988-07-26	Pickart Loren R	Use of GHL-Cu as a wound-healing and anti-inflammatory agent
US5120831A (en) *	1985-02-08	1992-06-09	Procyte Corporation	Metal-peptide compositions
US4810693A (en) *	1985-02-08	1989-03-07	Procyte Corporation	Method for inducing biological coverings in wounds
US5023237A (en) *	1989-08-30	1991-06-11	Procyte Corporation	Methods and compositions for healing ulcers
US5059588A (en) *	1989-10-13	1991-10-22	Procyte Corporation, Incorporated	Methods and compositions for healing bone using gly his lys: copper
US5386012A (en) *	1990-02-06	1995-01-31	Strid; Lars	Growth factor in connection with artificial implants
US5118665A (en) *	1990-02-09	1992-06-02	Procyte Corporation	Anti-oxidative and anti-inflammatory metal:peptide complexes and uses thereof
US5164367A (en) *	1990-03-26	1992-11-17	Procyte Corporation	Method of using copper(ii) containing compounds to accelerate wound healing

1994
- 1994-05-27 JP JP6115161A patent/JPH07316192A/ja active Pending
1995
- 1995-05-13 ES ES95107298T patent/ES2140575T3/es not_active Expired - Lifetime
- 1995-05-13 DK DK95107298T patent/DK0684259T3/da active
- 1995-05-13 EP EP95107298A patent/EP0684259B1/de not_active Expired - Lifetime
- 1995-05-13 DE DE69513324T patent/DE69513324T2/de not_active Expired - Fee Related
- 1995-05-13 AT AT95107298T patent/ATE186734T1/de not_active IP Right Cessation
- 1995-05-19 US US08/444,845 patent/US5591711A/en not_active Expired - Fee Related
- 1995-05-25 AU AU20289/95A patent/AU705569B2/en not_active Ceased
- 1995-05-26 KR KR1019950013381A patent/KR950032272A/ko not_active Abandoned
- 1995-05-26 CA CA002150334A patent/CA2150334A1/en not_active Abandoned
1999
- 1999-12-08 GR GR990403168T patent/GR3032077T3/el unknown

Also Published As

Publication number	Publication date
CA2150334A1 (en)	1995-11-28
US5591711A (en)	1997-01-07
ES2140575T3 (es)	2000-03-01
EP0684259B1 (de)	1999-11-17
KR950032272A (ko)	1995-12-20
AU2028995A (en)	1995-12-07
DK0684259T3 (da)	2000-05-08
AU705569B2 (en)	1999-05-27
DE69513324T2 (de)	2000-04-13
GR3032077T3 (en)	2000-03-31
EP0684259A1 (de)	1995-11-29
JPH07316192A (ja)	1995-12-05
DE69513324D1 (de)	1999-12-23

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Legal Events

Date	Code	Title	Description
2000-03-15	UEP	Publication of translation of european patent specification
2006-02-15	REN	Ceased due to non-payment of the annual fee