ATE186747T1 - Cytochrome p-450 reduktase screening für ergosterol biosynthese-inhibitoren - Google Patents

Cytochrome p-450 reduktase screening für ergosterol biosynthese-inhibitoren

Info

Publication number
ATE186747T1
ATE186747T1 AT94107752T AT94107752T ATE186747T1 AT E186747 T1 ATE186747 T1 AT E186747T1 AT 94107752 T AT94107752 T AT 94107752T AT 94107752 T AT94107752 T AT 94107752T AT E186747 T1 ATE186747 T1 AT E186747T1
Authority
AT
Austria
Prior art keywords
cytochrome
reductase
culture
preferred embodiments
test samples
Prior art date
Application number
AT94107752T
Other languages
English (en)
Inventor
Donald R Kirsch
Margaret Hsien-Fen Kuh Lai
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ATE186747T1 publication Critical patent/ATE186747T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT94107752T 1993-05-25 1994-05-19 Cytochrome p-450 reduktase screening für ergosterol biosynthese-inhibitoren ATE186747T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6689393A 1993-05-25 1993-05-25

Publications (1)

Publication Number Publication Date
ATE186747T1 true ATE186747T1 (de) 1999-12-15

Family

ID=22072383

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94107752T ATE186747T1 (de) 1993-05-25 1994-05-19 Cytochrome p-450 reduktase screening für ergosterol biosynthese-inhibitoren

Country Status (5)

Country Link
US (1) US6387647B1 (de)
EP (1) EP0626453B1 (de)
AT (1) ATE186747T1 (de)
DE (1) DE69421641T2 (de)
ES (1) ES2139034T3 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995006132A2 (en) * 1993-08-27 1995-03-02 Myco Pharmaceuticals, Incorporated Identifying biologically active agents through culture color change
GB9514184D0 (en) 1995-07-12 1995-09-13 Zeneca Ltd Assay
EP0972847A3 (de) * 1998-04-24 2000-02-09 Hoechst Marion Roussel Verfahren zur Detektion von Antimycotika
WO1999055907A2 (en) * 1998-04-24 1999-11-04 Hoechst Marion Roussel Method for screening antimycotic substances using essential genes from s. cerevisiae
EP0999284A1 (de) * 1998-09-11 2000-05-10 Hoechst Marion Roussel Verfahren zum Screening auf Antimykotika unter Verwendung essentieller Gene aus C.albicans, sowie die Gene selbst
GB9915399D0 (en) * 1999-07-02 1999-09-01 Zeneca Ltd Method
AU2001271985A1 (en) * 2000-07-12 2002-01-21 American Home Products Corporation Method for testing for inhibition of drug-metabolizing cytochrome p450 isozymes
JP2005512532A (ja) * 2001-08-03 2005-05-12 ディヴァーサ コーポレイション Ｐ４５０酵素、それらをコードした核酸及びそれらの作製と使用
DE10230224A1 (de) * 2002-07-04 2004-04-01 Axaron Bioscience Ag Verfahren zur Produktion von S-Adenosyl-L-Methionin durch Fermentation von genetisch modifizierten Mikroorganismen
US7700822B2 (en) * 2002-07-12 2010-04-20 Cancer Research Technology Limited Modulation of cytochrome P450 reductase activity
GB0216203D0 (en) * 2002-07-12 2002-08-21 Imp Cancer Res Tech Mondulation of cytochrome P450 reductase activity

Also Published As

Publication number Publication date
ES2139034T3 (es) 2000-02-01
EP0626453A1 (de) 1994-11-30
DE69421641D1 (de) 1999-12-23
DE69421641T2 (de) 2000-03-02
US6387647B1 (en) 2002-05-14
EP0626453B1 (de) 1999-11-17

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