ATE188217T1 - 1,2,3,4,10,14b-hexahydrodibenzo-c,f)pyrazino-1, - a)azepino-derivate - Google Patents

1,2,3,4,10,14b-hexahydrodibenzo-c,f)pyrazino-1, - a)azepino-derivate

Info

Publication number
ATE188217T1
ATE188217T1 AT88903139T AT88903139T ATE188217T1 AT E188217 T1 ATE188217 T1 AT E188217T1 AT 88903139 T AT88903139 T AT 88903139T AT 88903139 T AT88903139 T AT 88903139T AT E188217 T1 ATE188217 T1 AT E188217T1
Authority
AT
Austria
Prior art keywords
pct
lower alkyl
alkyl
hexahydrodibenzo
azepino
Prior art date
Application number
AT88903139T
Other languages
English (en)
Inventor
Frederick Charles Copp
Alan Louis Arthur Boura
William Roy Jackson
John David Cullen
Original Assignee
Univ Monash
Polychip Electronics Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Monash, Polychip Electronics Pty Ltd filed Critical Univ Monash
Application granted granted Critical
Publication of ATE188217T1 publication Critical patent/ATE188217T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT88903139T 1987-04-10 1988-03-31 1,2,3,4,10,14b-hexahydrodibenzo-c,f)pyrazino-1, - a)azepino-derivate ATE188217T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPI136387 1987-04-10
PCT/AU1988/000095 WO1988007997A1 (en) 1987-04-10 1988-03-31 1,2,3,4,10,14b-HEXAHYDRODIBENZO[c,f]PYRAZINO-[1,2-a]AZEPINO DERIVATIVES AND 10-AZA, 10-OXA AND 10-THIA ANALOGUES

Publications (1)

Publication Number Publication Date
ATE188217T1 true ATE188217T1 (de) 2000-01-15

Family

ID=3772107

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88903139T ATE188217T1 (de) 1987-04-10 1988-03-31 1,2,3,4,10,14b-hexahydrodibenzo-c,f)pyrazino-1, - a)azepino-derivate

Country Status (7)

Country Link
US (1) US5049637A (de)
EP (1) EP0379483B1 (de)
JP (1) JP2865255B2 (de)
AT (1) ATE188217T1 (de)
CA (1) CA1336773C (de)
DE (1) DE3856387T2 (de)
WO (1) WO1988007997A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2026925A1 (en) * 1989-10-05 1991-04-06 Hiroshi Fukumi Tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use
JPH04211071A (ja) * 1990-03-05 1992-08-03 Hokuriku Seiyaku Co Ltd 多環式化合物
EP0539164A1 (de) * 1991-10-23 1993-04-28 Sankyo Company Limited Stickstoff enthaltende tetracyclische Verbindungen mit antiallergischen und antiasthmatischen Wirkungen, ihre Herstellung und Verwendung
WO1999016769A1 (en) * 1997-09-26 1999-04-08 Monash University Resolution of optically-active compounds
JP2002506869A (ja) * 1998-03-17 2002-03-05 ノボ ノルディスク アクティーゼルスカブ 新規ヘテロ環式化合物
US6187770B1 (en) * 1998-03-17 2001-02-13 Novo Nordisk A/S N-substituted azaheterocyclic compounds
AU2002951965A0 (en) * 2002-10-09 2002-10-24 Monash University Amidine compounds
ITMI20042230A1 (it) * 2004-11-19 2005-02-19 Farchemia Srl Procedimento per la preparazione della 10,11-diidro-10 idrossi-5h-dibenz-b,f-azepin-5carbossiammide
US8518933B2 (en) 2009-04-23 2013-08-27 Abbvie Inc. Modulators of 5-HT receptors and methods of use thereof
CN102482292B (zh) * 2009-04-23 2017-07-18 Abbvie 公司 5‑ht受体的调节剂和其使用方法
US8546377B2 (en) 2009-04-23 2013-10-01 Abbvie Inc. Modulators of 5-HT receptors and methods of use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129434C (de) * 1966-03-12
NL154511B (nl) 1967-07-07 1977-09-15 Organon Nv Werkwijze ter bereiding van piperazinederivaten, werkwijze ter bereiding van een farmaceutisch preparaat, dat een dergelijke verbinding bevat en vormstukken bereid volgens deze werkwijze.
EP0126343A1 (de) * 1983-05-18 1984-11-28 Beecham Group Plc Behandlung der Diarrhöe

Also Published As

Publication number Publication date
DE3856387D1 (de) 2000-02-03
WO1988007997A1 (en) 1988-10-20
EP0379483A1 (de) 1990-08-01
JPH02503670A (ja) 1990-11-01
JP2865255B2 (ja) 1999-03-08
EP0379483A4 (en) 1991-10-09
CA1336773C (en) 1995-08-22
DE3856387T2 (de) 2000-05-11
EP0379483B1 (de) 1999-12-29
US5049637A (en) 1991-09-17

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Legal Events

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