ATE188733T1 - MODULE FOR BREEDING AND USING METABOLIC POWER AND/OR MAINTAINING MICROORGANISMS - Google Patents

MODULE FOR BREEDING AND USING METABOLIC POWER AND/OR MAINTAINING MICROORGANISMS

Info

Publication number
ATE188733T1
ATE188733T1 AT93114076T AT93114076T ATE188733T1 AT E188733 T1 ATE188733 T1 AT E188733T1 AT 93114076 T AT93114076 T AT 93114076T AT 93114076 T AT93114076 T AT 93114076T AT E188733 T1 ATE188733 T1 AT E188733T1
Authority
AT
Austria
Prior art keywords
module
breeding
hollow fibre
fibre membranes
microorganisms
Prior art date
Application number
AT93114076T
Other languages
German (de)
Inventor
Joerg Dr Gerlach
Original Assignee
Gerlach Joerg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gerlach Joerg filed Critical Gerlach Joerg
Application granted granted Critical
Publication of ATE188733T1 publication Critical patent/ATE188733T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10—Hollow fibers or tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/022—Artificial gland structures using bioreactors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Clinical Laboratory Science (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention relates to a module (1) for culturing and for utilising the metabolic activity for maintenance of microorganisms (9), in particular for cells or bacteria, consisting of an outer housing (2), at least three independent membrane systems, where at least two independent membrane systems are designed as hollow fibre membranes (3) and are arranged in the interior (4) of the module (1), and these hollow fibre membranes (3) form a tightly packed spatial network (5), and microoorganisms (9) which are located in the cavities of the network (5) and/or are adherent to the hollow fibre membranes (3). <IMAGE>
AT93114076T 1992-09-09 1993-09-02 MODULE FOR BREEDING AND USING METABOLIC POWER AND/OR MAINTAINING MICROORGANISMS ATE188733T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4230194A DE4230194C2 (en) 1992-09-09 1992-09-09 Reactor for the cultivation and use of metabolic services and / or for the maintenance of microorganisms

Publications (1)

Publication Number Publication Date
ATE188733T1 true ATE188733T1 (en) 2000-01-15

Family

ID=6467621

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93114076T ATE188733T1 (en) 1992-09-09 1993-09-02 MODULE FOR BREEDING AND USING METABOLIC POWER AND/OR MAINTAINING MICROORGANISMS

Country Status (5)

Country Link
US (1) US5516691A (en)
EP (1) EP0590341B1 (en)
JP (1) JP3420615B2 (en)
AT (1) ATE188733T1 (en)
DE (2) DE4230194C2 (en)

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JPH05320357A (en) * 1992-03-18 1993-12-03 Hitachi Ltd Method for stirring viscous substance and stirring apparatus
BE1009306A5 (en) * 1995-04-28 1997-02-04 Baxter Int Bioreactor.
US5827729A (en) * 1996-04-23 1998-10-27 Advanced Tissue Sciences Diffusion gradient bioreactor and extracorporeal liver device using a three-dimensional liver tissue
WO1998028064A1 (en) * 1996-12-21 1998-07-02 Akzo Nobel Nv Membrane module with hollow fibre membranes arranged in layers
US5955353A (en) * 1997-05-22 1999-09-21 Excorp Medical, Inc. Hollow fiber bioreactor with an extrafilament flow plug
DE19810901C1 (en) * 1998-03-13 1999-06-17 Ascalon Gesellscchaft Fuer Inn Bio-reactor assembly breeds micro-organisms, insects, plants, lactation cells, liver cells
ATE279225T1 (en) * 1998-07-26 2004-10-15 Klaus Rennebeck UREA PRODUCING ORGAN REPLACEMENT
US6410307B1 (en) 1999-03-09 2002-06-25 Acordis Industrial Fibers Gmbh Membrane module for testing active substances at cells
JP3553858B2 (en) * 1999-08-25 2004-08-11 東洋紡績株式会社 Cell culture module having a vascular network-like structure
WO2001066237A1 (en) * 2000-03-07 2001-09-13 Mat Adsorption Technologies Gmbh & Co. Kg Module with membrane elements in a cross-flow and in a dead-end arrangement
WO2003060061A1 (en) * 2001-12-21 2003-07-24 Organogenesis Inc. Chamber with adjustable volume for cell culture and organ assist
DE10242078A1 (en) * 2002-09-09 2004-03-18 Saxonia Bio Tec Gmbh Fiber cassette, for processing a variety of fluids, comprises a number of fibers and/or hollow fibers anchored in the housing at one end and with open fibers at the other end, giving a variety of configurations for a modular structure
ITMO20030081A1 (en) * 2003-03-21 2004-09-22 Rand Srl BIOREACTOR, PARTICULARLY FOR BIOARTIFICIAL BODIES.
DE10326749B4 (en) * 2003-06-13 2006-11-16 Gerlach, Jörg, Dr.med. Hybrid circulatory system
DE10326744B4 (en) * 2003-06-13 2006-03-23 Gerlach, Jörg, Dr.med. Module for breeding and utilization of metabolic activity and / or for obtaining microorganisms, process for its production and use
DE10326748B4 (en) * 2003-06-13 2006-11-23 Gerlach, Jörg, Dr.med. Nerve cell culture bioreactor and hybrid nerve cell system
CN100337698C (en) * 2003-06-24 2007-09-19 中国人民解放军第三军医大学 In vitro biologic artificial liver supporting device
DE102004007564A1 (en) * 2004-02-17 2005-09-01 Cordes, Rudolf, Dipl.-Ing. Device for breeding and mass production of algae
US7531351B2 (en) 2004-06-14 2009-05-12 Probiogen Ag Liquid-gas-phase exposure reactor for cell culturing
US7731852B2 (en) * 2004-12-13 2010-06-08 Aquarius Technologies Inc. Biomass support members and panels, biological processes and biological wastewater treatment apparatus
US7520980B2 (en) * 2004-12-13 2009-04-21 Aquarius Environmental Technologies Ltd. Bioreactor system for multi-stage biological wastewater treatment
DE102005021305A1 (en) * 2005-05-09 2006-11-16 Fresenius Medical Care Deutschland Gmbh Reactor unit comprises two of more chambers formed by the inner housing wall and a cylindrical layer of hollow fiber bundles embedded in sealing compound
EP2061871A1 (en) * 2006-09-14 2009-05-27 ProBioGen AG Modular culture system for maintenance, differentiation and proliferation of cells
CN101096639B (en) * 2007-05-16 2011-08-10 宁波 Multi-group fiber pipes even distributed multifunctional hollow fiber film pipe bioreactor
GB0808373D0 (en) * 2008-05-09 2008-06-18 Synexa Life Sciences Pty Ltd Scalable cell culture bioreactor and cell culture process
US8778669B2 (en) * 2009-07-22 2014-07-15 Corning Incorporated Multilayer tissue culture vessel
US20110155657A1 (en) * 2009-12-30 2011-06-30 Nephros, Inc. Tee-connector for use in a filtration system
EP2444478A1 (en) * 2010-10-22 2012-04-25 Gerlach, Jörg, Dr. med. Tubular body fluid mass exchange system and mass exchange device
US9005550B2 (en) 2012-10-29 2015-04-14 Corning Incorporated Multi-layered cell culture vessel with manifold grips
SG10202104562TA (en) 2016-11-03 2021-06-29 Univ Arizona Stacked tissue encapsulation device systems with or without oxygen delivery
KR20230037059A (en) 2016-11-03 2023-03-15 아리조나 보드 오브 리전츠 온 비해프 오브 더 유니버시티 오브 아리조나 Encapsulation device systems with oxygen sensors with or without exogenous oxygen delivery
US11746318B2 (en) 2016-11-03 2023-09-05 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods and systems for real-time assessment of cells in encapsulation devices pre-and post-transplantation
EP3534835B1 (en) * 2016-11-03 2025-05-14 Arizona Board of Regents on behalf of the University of Arizona Stacked tissue encapsulation device systems
JP6954381B2 (en) * 2018-01-24 2021-10-27 宇部興産株式会社 Cell culture module
WO2020069607A1 (en) 2018-10-01 2020-04-09 Membio Inc. Cell culture bioreactor
WO2021155469A1 (en) 2020-02-05 2021-08-12 Membio Inc. Cell culture bioreactor with zone control
US11492580B2 (en) * 2020-05-12 2022-11-08 Southwest Research Institute Method using a three-dimensional bioprocessor
WO2022094380A1 (en) 2020-10-30 2022-05-05 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods and systems for encapsulation devices for housing cells and agents

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US3734851A (en) * 1969-12-29 1973-05-22 K Matsumura Method and device for purifying blood
US4537860A (en) * 1982-12-08 1985-08-27 Monsanto Company Static cell culture maintenance system
FR2580514B1 (en) * 1985-04-17 1989-08-18 Lyonnaise Eaux COMPOSITE ASSEMBLY OF FILTRATION MEMBRANES AND ITS USE IN A BIOREACTOR
US4720462A (en) * 1985-11-05 1988-01-19 Robert Rosenson Culture system for the culture of solid tissue masses and method of using the same
US5043260A (en) * 1987-11-02 1991-08-27 Rhode Island Hospital Perfusion device with hepatocytes
US5081035A (en) * 1988-04-18 1992-01-14 The University Of Michigan Bioreactor system
JPH02109966A (en) * 1988-10-20 1990-04-23 Kirin Brewery Co Ltd Radial flow packed bed bioreactor
CH676677A5 (en) * 1989-01-27 1991-02-28 Sulzer Ag Permeable tubular membrane holding moving medium - transfers material to or from transversely flowing fluid medium
GB8921458D0 (en) * 1989-09-22 1989-11-08 Univ Strathclyde Cell culture apparatus
US5290366A (en) * 1990-03-08 1994-03-01 Siemens Solar Gmh Laminated solar module
FR2660323B1 (en) * 1990-03-30 1992-07-24 Bertin & Cie CELL CULTURE DEVICE.

Also Published As

Publication number Publication date
EP0590341A2 (en) 1994-04-06
DE4230194A1 (en) 1994-03-10
US5516691A (en) 1996-05-14
JPH06205665A (en) 1994-07-26
JP3420615B2 (en) 2003-06-30
EP0590341B1 (en) 2000-01-12
DE4230194C2 (en) 1995-07-27
DE59309926D1 (en) 2000-02-17
EP0590341A3 (en) 1995-04-05

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