ATE188743T1 - Oligonukleotiden komplementär zu mycobakterieller nukleinsäure - Google Patents
Oligonukleotiden komplementär zu mycobakterieller nukleinsäureInfo
- Publication number
- ATE188743T1 ATE188743T1 AT92918298T AT92918298T ATE188743T1 AT E188743 T1 ATE188743 T1 AT E188743T1 AT 92918298 T AT92918298 T AT 92918298T AT 92918298 T AT92918298 T AT 92918298T AT E188743 T1 ATE188743 T1 AT E188743T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- oligonucleotides
- oligonucleotides complementary
- mycobacterial nucleic
- mycobacteria
- Prior art date
Links
- 108091034117 Oligonucleotide Proteins 0.000 title abstract 4
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title abstract 3
- 230000000295 complement effect Effects 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004418 ribosomal RNA Proteins 0.000 abstract 3
- 230000003321 amplification Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 238000003752 polymerase chain reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/744,282 US5521300A (en) | 1991-08-13 | 1991-08-13 | Oligonucleotides complementary to mycobacterial nucleic acids |
| PCT/US1992/006821 WO1993004201A1 (en) | 1991-08-13 | 1992-08-13 | Oligonucleotides complementary to mycobacterial nucleic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE188743T1 true ATE188743T1 (de) | 2000-01-15 |
Family
ID=24992136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92918298T ATE188743T1 (de) | 1991-08-13 | 1992-08-13 | Oligonukleotiden komplementär zu mycobakterieller nukleinsäure |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5521300A (de) |
| EP (1) | EP0552358B1 (de) |
| JP (1) | JPH06502312A (de) |
| AT (1) | ATE188743T1 (de) |
| DE (1) | DE69230555T2 (de) |
| WO (1) | WO1993004201A1 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7009041B1 (en) * | 1989-07-11 | 2006-03-07 | Gen-Probe Incorporated | Oligonucleotides for nucleic acid amplification and for the detection of Mycobacterium tuberculosis |
| US5766849A (en) * | 1989-07-11 | 1998-06-16 | Gen-Probe Incorporated | Methods of amplifying nucleic acids using promoter-containing primer sequence |
| JP4090498B2 (ja) * | 1992-04-28 | 2008-05-28 | ジェン−プローブ・インコーポレイテッド | マイコバクテリウム・ツベルクロシスのための核酸プロセスプローブ |
| CA2141430C (en) * | 1992-08-04 | 2009-05-12 | Sherrol H. Mcdonough | Nucleic acid sequence amplification |
| FR2709310B1 (fr) * | 1993-07-23 | 1995-09-29 | Bio Merieux | Fragment nucléotidique de l'ARN ribosomique 23S de mycobactéries, sondes et amorces dérivées, réactif et procédé de détection. |
| US6136529A (en) * | 1993-09-03 | 2000-10-24 | Gen-Probe Incorporated | Nucleic acid probes to Mycobacterium avium complex |
| US5631130A (en) * | 1994-05-13 | 1997-05-20 | Abbott Laboratories | Materials and methods for the detection of Mycobacterium tuberculosis |
| WO1995031571A2 (en) * | 1994-05-13 | 1995-11-23 | Abbott Laboratories | Materials and methods for the detection of mycobacteria |
| US5712095A (en) * | 1994-06-16 | 1998-01-27 | Becton Dickinson And Company | Rapid and sensitive detection of antibiotic-resistant mycobacteria using oligonucleotide probes specific for ribosomal RNA precursors |
| US6025132A (en) * | 1994-06-24 | 2000-02-15 | Innogenetics N.V. | Probes targeted to rRNA spacer regions, methods and kits for using said probes, for the detection of respiratory tract pathogens |
| US5656427A (en) * | 1994-08-29 | 1997-08-12 | Gen-Probe Incorporated | Nucleic acid hybridization assay probes, helper probes and amplification oligonucleotides targeted to Mycoplasma pneumoniae nucleic acid |
| FR2730234B1 (fr) * | 1995-02-08 | 1997-03-28 | Bio Merieux | Detection de bacteries du genre listeria selon des techniques d'hybridation de sondes nucleiques |
| US5616465A (en) | 1995-08-09 | 1997-04-01 | The Regents Of The University Of California | Detection and isolation of nucleic acid sequences using competitive hybridization probes |
| US5811269A (en) * | 1996-04-30 | 1998-09-22 | Becton, Dickinson And Company | Detection of mycobacteria by multiplex nucleic acid amplification |
| DE69723096T2 (de) * | 1996-10-04 | 2004-05-06 | Dako A/S | Sonden zur detektion von mycobakterien |
| US6558901B1 (en) * | 1997-05-02 | 2003-05-06 | Biomerieux Vitek | Nucleic acid assays |
| IL124275A (en) * | 1997-05-02 | 2002-03-10 | Bio Merieux Vitek Inc | A method to produce sequences of nucleic acids |
| US5985569A (en) * | 1997-09-26 | 1999-11-16 | Becton, Dickinson And Company | Primers for amplification of a genus specific sequence of the mycobacterium 16S rRNA gene |
| US6384204B1 (en) * | 1998-07-27 | 2002-05-07 | Evan Samuel Deneris | Reagents and methods for the screening of compounds useful in the treatment of neurological diseases |
| GB9904804D0 (en) | 1999-03-02 | 1999-04-28 | King S College London | Identification of bacteria |
| US6821770B1 (en) | 1999-05-03 | 2004-11-23 | Gen-Probe Incorporated | Polynucleotide matrix-based method of identifying microorganisms |
| DE19945916A1 (de) * | 1999-09-24 | 2001-04-05 | Biotecon Diagnostics Gmbh | Nukleinsäuremoleküle zum Nachweis von Bakterien und phylogenetischen Einheiten von Bakterien |
| AU2074101A (en) * | 1999-12-08 | 2001-06-18 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer |
| US6664081B2 (en) * | 1999-12-17 | 2003-12-16 | Gen-Probe Incorporated | Nucleic acid amplification and detection of mycobacterium species |
| US7271781B2 (en) * | 2000-03-03 | 2007-09-18 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Multiplex hybridization system for identification of pathogenic mycobacterium and method of use |
| US6825336B1 (en) * | 2000-09-08 | 2004-11-30 | Applera Corporation | Polymorphisms in known genes associated with osteoporosis, methods of detection and uses thereof |
| JP3479684B2 (ja) * | 2000-09-21 | 2003-12-15 | 独立行政法人食品総合研究所 | サッカロマイセス・セレビシエに属する酵母のミトコンドリア２１ｓリボゾームｒｎａ遺伝子の簡易迅速な塩基配列決定法 |
| WO2003016574A1 (en) * | 2001-08-16 | 2003-02-27 | Zhifeng Shao | Analysis of gene expression profiles using sequential hybridization |
| WO2004067702A2 (en) * | 2003-01-30 | 2004-08-12 | The University Of Warwick | Methods, oligonucleotides and kits for the identification of mycobacterium in a sample |
| WO2006137939A2 (en) * | 2004-11-09 | 2006-12-28 | Gen-Probe Incorporated | Compositions and methods for detecting group a streptococci |
| US8758990B2 (en) * | 2005-07-28 | 2014-06-24 | Id-Fish Technology, Inc. | Methods for detecting and differentiating Mycobacterium genus and Mycobacterium avium complex in a sample or culture |
| CA2641599C (en) * | 2005-07-28 | 2012-07-10 | Id-Fish Technology, Inc. | Method for improving cell permeability to foreign particles |
| GB0526033D0 (en) | 2005-12-21 | 2006-02-01 | Bioeos Ltd | Method |
| CA2651946A1 (en) * | 2006-05-12 | 2007-11-22 | Gen-Probe Incorporated | Compositions and methods to detect enterococci nucleic acid |
| EP2027293B1 (de) * | 2006-05-24 | 2014-11-19 | Gen-Probe Incorporated | Verfahren zum lysieren von mycobacterium und amplifikation seiner nukleinsäuren |
| EP1985712A1 (de) * | 2007-04-17 | 2008-10-29 | Vereniging voor christelijk hoger onderwijs, wetenschappelijk onderzoek en patiëntenzorg | Analyse einer mikrobiellen Population |
| JP2011188855A (ja) * | 2010-03-11 | 2011-09-29 | Samsung Techwin Co Ltd | 切断可能なキメラプローブを使用したサルモネラのリアルタイム検出方法 |
| TW202108771A (zh) * | 2019-05-03 | 2021-03-01 | 美商梅梭刻度技術公司 | 用於偵測樣本中之一或多個目標分析物之套組及其製備及使用方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4410660A (en) * | 1980-05-05 | 1983-10-18 | Montefiore Medical Center | Binding assay for the detection of mycobacteria |
| US4489158A (en) * | 1980-05-05 | 1984-12-18 | Montefiore Hospital And Medical Center, Inc. | Binding assay for the detection of mycobacteria |
| US4575484A (en) * | 1980-05-05 | 1986-03-11 | Montefiore Medical Center, Inc. | Binding assay for the detection of mycobacteria |
| US4358535A (en) * | 1980-12-08 | 1982-11-09 | Board Of Regents Of The University Of Washington | Specific DNA probes in diagnostic microbiology |
| WO1988003957A1 (en) * | 1986-11-24 | 1988-06-02 | Gen-Probe Incorporated | Nucleic acid probes for detection and/or quantitation of non-viral organisms |
| EP0418346A1 (de) * | 1989-02-06 | 1991-03-27 | Gene-Trak Systems | Sonden und verfahren zum nachweis von listeria |
-
1991
- 1991-08-13 US US07/744,282 patent/US5521300A/en not_active Expired - Fee Related
-
1992
- 1992-08-13 DE DE69230555T patent/DE69230555T2/de not_active Expired - Fee Related
- 1992-08-13 JP JP5504448A patent/JPH06502312A/ja not_active Ceased
- 1992-08-13 EP EP92918298A patent/EP0552358B1/de not_active Expired - Lifetime
- 1992-08-13 AT AT92918298T patent/ATE188743T1/de not_active IP Right Cessation
- 1992-08-13 WO PCT/US1992/006821 patent/WO1993004201A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1993004201A1 (en) | 1993-03-04 |
| DE69230555D1 (de) | 2000-02-17 |
| DE69230555T2 (de) | 2000-08-24 |
| EP0552358B1 (de) | 2000-01-12 |
| JPH06502312A (ja) | 1994-03-17 |
| US5521300A (en) | 1996-05-28 |
| EP0552358A1 (de) | 1993-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |