ATE189396T1 - Hydroxyaryl enthaltenden aminocarboxylsäure- chelatbildnern - Google Patents

Hydroxyaryl enthaltenden aminocarboxylsäure- chelatbildnern

Info

Publication number: ATE189396T1
Authority: AT; Austria
Prior art keywords: sulphamoyl; carbamoyl; integer; aminocarboxylic acid; hydroxy
Prior art date: 1992-07-31

Application number

AT93305992T

Other languages

English (en)

Inventor

Suzanne Virginia Smith

Richard Merle Lambrecht

Peter Frederick Schmidt

Fook-Thean Lee

Original Assignee

Australian Nuclear Science Tec

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-07-31

Filing date

1993-07-29

Publication date

2000-02-15

1993-07-29 Application filed by Australian Nuclear Science Tec filed Critical Australian Nuclear Science Tec

2000-02-15 Application granted granted Critical

2000-02-15 Publication of ATE189396T1 publication Critical patent/ATE189396T1/de

Links

KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical compound NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 title 1
239000002738 chelating agent Substances 0.000 title 1
-1 hydroxy, mercapto, nitro, cyano, thiocyano Chemical group 0.000 abstract 6
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
125000004442 acylamino group Chemical group 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
SMWDFEZZVXVKRB-UHFFFAOYSA-N anhydrous quinoline Natural products N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000003745 diagnosis Methods 0.000 abstract 1
125000001188 haloalkyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Optics & Photonics (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Physics & Mathematics (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Quinoline Compounds (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT93305992T 1992-07-31 1993-07-29 Hydroxyaryl enthaltenden aminocarboxylsäure- chelatbildnern ATE189396T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
AUPL388392		1992-07-31

Publications (1)

Publication Number	Publication Date
ATE189396T1 true ATE189396T1 (de)	2000-02-15

Family

ID=3776332

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93305992T ATE189396T1 (de)	1992-07-31	1993-07-29	Hydroxyaryl enthaltenden aminocarboxylsäure- chelatbildnern

Country Status (8)

Country	Link
US (1)	US5550160A (de)
EP (2)	EP0590766B1 (de)
JP (1)	JPH07285888A (de)
AT (1)	ATE189396T1 (de)
DE (1)	DE69327760T2 (de)
ES (1)	ES2146217T3 (de)
GR (1)	GR3033352T3 (de)
PT (1)	PT590766E (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5807535A (en) *	1992-07-31	1998-09-15	Australian Nuclear Science & Technology Organisation	Metal complexes of hydroxyaryl containing aminocarboxylic acid chelating agents
FR2794032B1 (fr)	1999-05-27	2002-06-14	Univ Claude Bernard Lyon	Procede pour separer en milieu aqueux des lanthanides et/ou des actinides par complexation-nanofiltration, et nouveaux complexants mis en oeuvre dans ce procede

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3632637A (en) *	1968-02-13	1972-01-04	Arthur E Martell	Hydroxyaryl-containing aminocarboxylic chelating agents
BE786946A (fr) *	1971-07-29	1973-01-29	Ciba Geigy	Chelates pour combattre des symptomes de carences en metaux dans des systemes biologiques
AT392004B (de) *	1981-10-27	1991-01-10	Hybritech Inc	Verfahren zur herstellung eines monoklonalen antikoerpers gegen tumor-assoziiertes antigen und dessen verwendung
CA1222691A (en) *	1981-12-29	1987-06-09	Wilhelmus T. Goedemans	Method of preparing radionuclide-labelled proteins, in particular antibodies or antibody fragments
US4479930A (en) *	1982-07-26	1984-10-30	Trustees Of The University Of Massachusetts	Amines coupled wth dicyclic dianhydrides capable of being radiolabeled product
AU572125B2 (en) *	1983-03-17	1988-05-05	Mabco Limited	Monoclonal antibodies with specificity for crosslinked fibrin and their diagnotic uses
US4652440A (en) *	1984-05-03	1987-03-24	Paik Chang H	Method of stably radiolabeling antibodies with technetium and rhenium
GB8603537D0 (en) *	1986-02-13	1986-03-19	Parker D	Conjugate compound
DE3640708C2 (de) *	1986-11-28	1995-05-18	Schering Ag	Verbesserte metallhaltige Pharmazeutika
DE3713842A1 (de) *	1987-04-22	1988-11-17	Schering Ag	Substituierte cyclische komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel
IL87405A0 (en) *	1987-08-12	1989-01-31	Immunomedics Inc	Radiolabeled agents and methods and kits for the production thereof
GB8719042D0 (en) *	1987-08-12	1987-09-16	Parker D	Conjugate compounds
GB8719041D0 (en) *	1987-08-12	1987-09-16	Parker D	Conjugate compounds
ATE134999T1 (de) *	1988-05-25	1996-03-15	Us Commerce	Makrocyclische chelate und verwendungsverfahren
US5094950A (en) *	1988-06-07	1992-03-10	Nihon Medi-Physics Co., Ltd.	Diethylenetriamine pentaacetic acid derivatives
JP2776953B2 (ja) *	1990-04-10	1998-07-16	日本メジフィジックス株式会社	多官能性金属キレート化合物とその用途
GB9027922D0 (en) *	1990-12-21	1991-02-13	Nycomed As	Compounds

1993
- 1993-07-29 PT PT93305992T patent/PT590766E/pt unknown
- 1993-07-29 EP EP93305992A patent/EP0590766B1/de not_active Expired - Lifetime
- 1993-07-29 EP EP99112338A patent/EP0955066A3/de not_active Withdrawn
- 1993-07-29 DE DE69327760T patent/DE69327760T2/de not_active Expired - Fee Related
- 1993-07-29 AT AT93305992T patent/ATE189396T1/de not_active IP Right Cessation
- 1993-07-29 ES ES93305992T patent/ES2146217T3/es not_active Expired - Lifetime
- 1993-07-29 US US08/099,179 patent/US5550160A/en not_active Expired - Fee Related
- 1993-07-31 JP JP5208689A patent/JPH07285888A/ja active Pending
2000
- 2000-05-02 GR GR20000401036T patent/GR3033352T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
GR3033352T3 (en)	2000-09-29
US5550160A (en)	1996-08-27
EP0590766A3 (en)	1994-08-24
JPH07285888A (ja)	1995-10-31
PT590766E (pt)	2000-07-31
EP0590766A2 (de)	1994-04-06
EP0590766B1 (de)	2000-02-02
EP0955066A2 (de)	1999-11-10
EP0955066A3 (de)	2002-08-28
DE69327760T2 (de)	2000-09-07
ES2146217T3 (es)	2000-08-01
DE69327760D1 (de)	2000-03-09

Legal Events

Date	Code	Title	Description
2000-08-15	UEP	Publication of translation of european patent specification
2002-04-15	REN	Ceased due to non-payment of the annual fee

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ES554895A0 (es)	1988-04-01	Un procedimiento para preparar derivados de (benzoil-4-piperidinil-1)-2-fenil-1-alcanoles
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TR199700844T1 (xx)	1998-01-21	Pirazolil-Benzoil T�revleri.
EA199700209A1 (ru)	1998-04-30	ПРОИЗВОДНЫЕ ИМИДАЗО[1,2-a]ПИРИДИНА
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AU553927B2 (en)	1986-07-31	Oxazolo- thiazolo- imidazolo (5,4-b) pyridines
SE8101211L (sv)	1981-10-12	Antihypertensiva aminer
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DE69327760D1 (de)	2000-03-09	Hydroxyaryl enthaltenden aminocarboxylsäure-chelatbildnern
NO171786C (no)	1993-05-05	Analogifremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater
DE69302087D1 (de)	1996-05-09	Trazodone alkyl derivate mit zns wirkung
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DK347387A (da)	1987-07-06	Amidderivater
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SE8006142L (sv)	1981-03-05	1,2,4-triazol-3-tioler
EA200200462A1 (ru)	2002-10-31	Производные 2-арилхинолина, их получение и терапевтическое применение