ATE191476T1 - Verfahren zur herstellung von indolderivaten - Google Patents

Verfahren zur herstellung von indolderivaten

Info

Publication number
ATE191476T1
ATE191476T1 AT91305602T AT91305602T ATE191476T1 AT E191476 T1 ATE191476 T1 AT E191476T1 AT 91305602 T AT91305602 T AT 91305602T AT 91305602 T AT91305602 T AT 91305602T AT E191476 T1 ATE191476 T1 AT E191476T1
Authority
AT
Austria
Prior art keywords
indole derivatives
producing indole
acid
producing
methylbenzenemethanesulphonamide
Prior art date
Application number
AT91305602T
Other languages
English (en)
Inventor
Frederick David Albinson
Derek Leslie Crookes
John Wilson Macfarla Mackinnon
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE191476T1 publication Critical patent/ATE191476T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT91305602T 1990-06-21 1991-06-20 Verfahren zur herstellung von indolderivaten ATE191476T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909013845A GB9013845D0 (en) 1990-06-21 1990-06-21 Process

Publications (1)

Publication Number Publication Date
ATE191476T1 true ATE191476T1 (de) 2000-04-15

Family

ID=10677976

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91305602T ATE191476T1 (de) 1990-06-21 1991-06-20 Verfahren zur herstellung von indolderivaten

Country Status (8)

Country Link
US (1) US5103020A (de)
EP (1) EP0462837B1 (de)
JP (1) JP3166125B2 (de)
AT (1) ATE191476T1 (de)
DE (1) DE69132091T2 (de)
DK (1) DK0462837T3 (de)
ES (1) ES2144995T3 (de)
GB (1) GB9013845D0 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133453A (en) * 1998-05-15 2000-10-17 Pharm-Eco Laboratories, Inc. Method for making substituted indoles
CN1729174B (zh) 2002-12-20 2015-10-21 西巴特殊化学品控股有限公司 胺的合成以及用于合成胺的中间体
JP5833804B2 (ja) 2005-04-13 2015-12-16 ニューラクソン，インコーポレーテッド Ｎｏｓ阻害活性を有する置換インドール化合物
AU2007240078B2 (en) * 2006-04-13 2013-07-25 Neuraxon, Inc. 1,5 and 3,6- substituted indole compounds having NOS inhibitory activity
CN100554252C (zh) * 2007-07-17 2009-10-28 浙江苏泊尔制药有限公司 一种琥珀酸舒马曲坦的制备方法
EP2220074A4 (de) * 2007-11-16 2012-01-04 Neuraxon Inc 3,5-substituierte indolverbindungen mit nos- und norepinephrin-wiederaufnahme-hemmender wirkung
KR20100103799A (ko) * 2007-11-16 2010-09-28 네우렉슨 인코포레이티드 내장통을 치료하기 위한 인돌 화합물 및 방법
EP2219449A4 (de) * 2007-11-16 2010-10-27 Univ Arizona State Verfahren zum behandeln von darmschmerzen
CN102432519B (zh) * 2011-11-21 2013-12-11 山东新华制药股份有限公司 3-(2-氨乙基)-n-甲基-1h-吲哚-5-甲烷磺酰胺的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55105664A (en) * 1979-02-08 1980-08-13 Kawaken Fine Chem Co Ltd Preparation of tryptamine
IT1170387B (it) * 1982-06-07 1987-06-03 Glaxo Group Ltd Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono
GB2162522B (en) * 1984-08-01 1988-02-24 Glaxo Group Ltd An indole derivative
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds

Also Published As

Publication number Publication date
DK0462837T3 (da) 2000-09-11
DE69132091T2 (de) 2000-10-12
EP0462837A3 (en) 1992-09-23
DE69132091D1 (de) 2000-05-11
EP0462837A2 (de) 1991-12-27
JP3166125B2 (ja) 2001-05-14
ES2144995T3 (es) 2000-07-01
US5103020A (en) 1992-04-07
JPH04230258A (ja) 1992-08-19
GB9013845D0 (en) 1990-08-15
EP0462837B1 (de) 2000-04-05

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee