ATE193557T1 - Anti-mikrobische agenzien und screening-verfahren dazu - Google Patents
Anti-mikrobische agenzien und screening-verfahren dazuInfo
- Publication number
- ATE193557T1 ATE193557T1 AT94911230T AT94911230T ATE193557T1 AT E193557 T1 ATE193557 T1 AT E193557T1 AT 94911230 T AT94911230 T AT 94911230T AT 94911230 T AT94911230 T AT 94911230T AT E193557 T1 ATE193557 T1 AT E193557T1
- Authority
- AT
- Austria
- Prior art keywords
- substance
- dbpa
- inhibition
- extent
- screening methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 230000003377 anti-microbal effect Effects 0.000 title 1
- 238000012216 screening Methods 0.000 title 1
- 101100431670 Rattus norvegicus Ybx3 gene Proteins 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 3
- 229910019142 PO4 Inorganic materials 0.000 abstract 2
- 230000005764 inhibitory process Effects 0.000 abstract 2
- 239000002777 nucleoside Substances 0.000 abstract 2
- -1 nucleoside phosphate Chemical class 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 239000010452 phosphate Substances 0.000 abstract 2
- 102000045595 Phosphoprotein Phosphatases Human genes 0.000 abstract 1
- 108700019535 Phosphoprotein Phosphatases Proteins 0.000 abstract 1
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 abstract 1
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 abstract 1
- 108090000944 RNA Helicases Proteins 0.000 abstract 1
- 102000004409 RNA Helicases Human genes 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108020004418 ribosomal RNA Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939306416A GB9306416D0 (en) | 1993-03-27 | 1993-03-27 | Anti-microbial agent |
| GB9401532A GB9401532D0 (en) | 1994-01-27 | 1994-01-27 | Anti-microbial agent |
| PCT/GB1994/000649 WO1994023059A2 (en) | 1993-03-27 | 1994-03-28 | Anti-microbial agents and screening method therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE193557T1 true ATE193557T1 (de) | 2000-06-15 |
Family
ID=26302662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94911230T ATE193557T1 (de) | 1993-03-27 | 1994-03-28 | Anti-mikrobische agenzien und screening-verfahren dazu |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6020149A (de) |
| EP (1) | EP0690924B1 (de) |
| JP (1) | JP3517243B2 (de) |
| CN (1) | CN1061098C (de) |
| AT (1) | ATE193557T1 (de) |
| AU (1) | AU6380094A (de) |
| CA (1) | CA2159112C (de) |
| DE (1) | DE69424780T2 (de) |
| DK (1) | DK0690924T3 (de) |
| WO (1) | WO1994023059A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10509875A (ja) * | 1994-12-02 | 1998-09-29 | ビイク グルデン ロンベルク ヒェーミッシェ ファブリーク ゲゼルシャフト ミット ベシュレンクテル ハフツング | スクリーニングモデル |
| DE19545126A1 (de) | 1995-12-04 | 1997-06-05 | Hoechst Ag | ATP- und Nukleinsäure-bindendes Protein mit Helikase-Eigenschaften |
| WO2000042214A1 (en) * | 1999-01-15 | 2000-07-20 | Pantherix Ltd. | Phosphate release enzyme assay |
| EP1399562A2 (de) * | 2000-07-19 | 2004-03-24 | PHARMACIA & UPJOHN COMPANY | Vollständige staphylococcus aureus ribosomales protein s20 gen nukleotidsequenz und verfahren zur identifizierung von antibakterielle substanzen |
| WO2005032329A2 (en) * | 2003-08-22 | 2005-04-14 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for identifying anti-hcv agents |
| CN104611419B (zh) * | 2014-12-29 | 2016-08-24 | 江苏大学 | 一种基于石墨烯氧化物芯片dna解旋酶的检测方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4416995A (en) * | 1981-09-10 | 1983-11-22 | Bronx-Lebanon Hospital Center | Method and apparatus for determining bacterial sensitivity |
| JPH0213382A (ja) * | 1988-03-30 | 1990-01-17 | Monsanto Co | グラムネガテイブ微生物での構造遺伝子の調節発現法 |
| US5466576A (en) * | 1993-07-02 | 1995-11-14 | Fred Hutchinson Cancer Research Center | Modulation of PIF-1-type helicases |
-
1994
- 1994-03-28 WO PCT/GB1994/000649 patent/WO1994023059A2/en not_active Ceased
- 1994-03-28 CA CA002159112A patent/CA2159112C/en not_active Expired - Fee Related
- 1994-03-28 AU AU63800/94A patent/AU6380094A/en not_active Abandoned
- 1994-03-28 CN CN94191619A patent/CN1061098C/zh not_active Expired - Fee Related
- 1994-03-28 EP EP94911230A patent/EP0690924B1/de not_active Expired - Lifetime
- 1994-03-28 DK DK94911230T patent/DK0690924T3/da active
- 1994-03-28 AT AT94911230T patent/ATE193557T1/de not_active IP Right Cessation
- 1994-03-28 DE DE69424780T patent/DE69424780T2/de not_active Expired - Fee Related
- 1994-03-28 JP JP52181294A patent/JP3517243B2/ja not_active Expired - Fee Related
-
1997
- 1997-09-15 US US08/929,738 patent/US6020149A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1994023059A2 (en) | 1994-10-13 |
| CN1061098C (zh) | 2001-01-24 |
| DK0690924T3 (da) | 2000-10-09 |
| DE69424780D1 (de) | 2000-07-06 |
| DE69424780T2 (de) | 2001-02-15 |
| EP0690924A1 (de) | 1996-01-10 |
| JP3517243B2 (ja) | 2004-04-12 |
| CA2159112C (en) | 2007-06-19 |
| WO1994023059A3 (en) | 1995-01-05 |
| CN1120353A (zh) | 1996-04-10 |
| AU6380094A (en) | 1994-10-24 |
| CA2159112A1 (en) | 1994-10-13 |
| EP0690924B1 (de) | 2000-05-31 |
| JPH08511416A (ja) | 1996-12-03 |
| US6020149A (en) | 2000-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |