ATE193597T1 - Zeitaufgelöste optische sensorarrays und ccd- kameras zur frequenzbereich-fluorimetrie und/oder phosphorimetrie - Google Patents

Zeitaufgelöste optische sensorarrays und ccd- kameras zur frequenzbereich-fluorimetrie und/oder phosphorimetrie

Info

Publication number
ATE193597T1
ATE193597T1 AT93309155T AT93309155T ATE193597T1 AT E193597 T1 ATE193597 T1 AT E193597T1 AT 93309155 T AT93309155 T AT 93309155T AT 93309155 T AT93309155 T AT 93309155T AT E193597 T1 ATE193597 T1 AT E193597T1
Authority
AT
Austria
Prior art keywords
frequency
signal
phosphorimetry
radiation
fluorimetry
Prior art date
Application number
AT93309155T
Other languages
English (en)
Inventor
Enrico Gratton
Ven Martin Vande
Beniamino Barbieri
Original Assignee
Enrico Gratton
Ven Martin Vande
Beniamino Barbieri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enrico Gratton, Ven Martin Vande, Beniamino Barbieri filed Critical Enrico Gratton
Application granted granted Critical
Publication of ATE193597T1 publication Critical patent/ATE193597T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406—Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1765—Method using an image detector and processing of image signal
    • G01N2021/177—Detector of the video camera type
    • G01N2021/1772—Array detector
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1789—Time resolved

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Photometry And Measurement Of Optical Pulse Characteristics (AREA)
  • Spectrometry And Color Measurement (AREA)
AT93309155T 1992-12-01 1993-11-17 Zeitaufgelöste optische sensorarrays und ccd- kameras zur frequenzbereich-fluorimetrie und/oder phosphorimetrie ATE193597T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/983,829 US5323010A (en) 1992-12-01 1992-12-01 Time resolved optical array detectors and CCD cameras for frequency domain fluorometry and/or phosphorimetry

Publications (1)

Publication Number Publication Date
ATE193597T1 true ATE193597T1 (de) 2000-06-15

Family

ID=25530126

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93309155T ATE193597T1 (de) 1992-12-01 1993-11-17 Zeitaufgelöste optische sensorarrays und ccd- kameras zur frequenzbereich-fluorimetrie und/oder phosphorimetrie

Country Status (6)

Country Link
US (1) US5323010A (de)
EP (1) EP0600633B1 (de)
JP (1) JPH07306140A (de)
AT (1) ATE193597T1 (de)
CA (1) CA2103077A1 (de)
DE (1) DE69328762T2 (de)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6064819A (en) * 1993-12-08 2000-05-16 Imec Control flow and memory management optimization
JP3364333B2 (ja) * 1994-09-19 2003-01-08 浜松ホトニクス株式会社 減衰特性測定装置
US5757013A (en) * 1995-12-06 1998-05-26 American Research Corporation Of Virginia Fluorescence decay measurement by calculation of inner product
US5994707A (en) * 1997-03-18 1999-11-30 Physical Optics Corporation Modular fiber optic fluorometer and method of use thereof
WO1999001737A2 (en) * 1997-06-10 1999-01-14 Calspan Corporation Detection of chemical agent materials using a sorbent polymer and fluorescent probe
US6469311B1 (en) 1997-07-16 2002-10-22 Molecular Devices Corporation Detection device for light transmitted from a sensed volume
US6071748A (en) 1997-07-16 2000-06-06 Ljl Biosystems, Inc. Light detection device
GB9717194D0 (en) * 1997-08-13 1997-10-22 De La Rue Thomas & Co Ltd Detector methods and apparatus
US6982431B2 (en) 1998-08-31 2006-01-03 Molecular Devices Corporation Sample analysis systems
US6992761B2 (en) * 1997-09-20 2006-01-31 Molecular Devices Corporation Broad range light detection system
US6576476B1 (en) 1998-09-02 2003-06-10 Ljl Biosystems, Inc. Chemiluminescence detection method and device
US6825921B1 (en) 1999-11-10 2004-11-30 Molecular Devices Corporation Multi-mode light detection system
US6297018B1 (en) 1998-04-17 2001-10-02 Ljl Biosystems, Inc. Methods and apparatus for detecting nucleic acid polymorphisms
WO2000050877A1 (en) 1999-02-23 2000-08-31 Ljl Biosystems, Inc. Frequency-domain light detection device
US6326605B1 (en) 1998-02-20 2001-12-04 Ljl Biosystems, Inc. Broad range light detection system
US5982334A (en) * 1997-10-31 1999-11-09 Waveband Corporation Antenna with plasma-grating
DE19806178C2 (de) * 1998-02-02 2001-03-01 Deutsche Telekom Ag Verfahren und Anordnung zur Erzeugung binärer Sequenzen von Zufallszahlen
US6078833A (en) * 1998-03-25 2000-06-20 I.S.S. (Usa) Inc. Self referencing photosensor
AU5223899A (en) 1998-07-27 2000-02-21 Ljl Biosystems, Inc. Apparatus and methods for spectroscopic measurements
AU5667599A (en) 1998-07-27 2000-02-21 Ljl Biosystems, Inc. Apparatus and methods for time-resolved spectroscopic measurements
US6184534B1 (en) * 1998-08-04 2001-02-06 Eastman Kodak Company Method of pulsing light emitting diodes for reading fluorescent indicia, data reader, and system
US6300638B1 (en) 1998-11-12 2001-10-09 Calspan Srl Corporation Modular probe for total internal reflection fluorescence spectroscopy
JP2000283960A (ja) * 1999-03-31 2000-10-13 Shimadzu Corp マイクロチップ電気泳動装置
US6690098B1 (en) * 2000-01-31 2004-02-10 Litton Systems, Inc. Method and system for gating a power supply in a radiation detector
FR2814817B1 (fr) * 2000-10-04 2003-01-31 Sagem Detection de debris spatiaux en orbite a partir d'un instrument embarque sur satellite
US6673626B1 (en) 2000-10-31 2004-01-06 Science & Technology Corporation University Of New Mexico Optoelectronic circuit for detecting changes in fluorescence lifetime
US6740890B1 (en) * 2001-08-15 2004-05-25 Chen-Yu Tai Time-resolved light decay measurements without using a gated detector
MXPA04002498A (es) * 2001-09-19 2005-04-11 Joule Microsystems Canada Inc Un espectrometro que incorpora filtrado ajustado de senal.
US7041986B2 (en) * 2002-03-14 2006-05-09 University Of Maryland Baltimore County Device for discrimination of fluorescence lifetimes and uses therefor
DE10217940A1 (de) * 2002-04-22 2003-11-13 Rainer Bayer Mikrospektrometer
GB0226356D0 (en) * 2002-11-12 2002-12-18 Multiplex Photonics Ltd Method of material analysis
FR2856792B1 (fr) * 2003-06-27 2006-09-15 Commissariat Energie Atomique Procede et dispositif de dosage d'un echantillon biologique ou chimique
ES2244296B1 (es) * 2003-10-03 2007-02-01 Signe, S.A. Sistema de medicion de fosforo y procedimiento asociado.
US7274028B2 (en) * 2005-07-14 2007-09-25 The Boeing Company Characterizing fluorescent and/or phosphorescent materials
US7736382B2 (en) 2005-09-09 2010-06-15 Lockheed Martin Corporation Apparatus for optical stimulation of nerves and other animal tissue
US8744570B2 (en) 2009-01-23 2014-06-03 Lockheed Martin Corporation Optical stimulation of the brainstem and/or midbrain, including auditory areas
US8475506B1 (en) 2007-08-13 2013-07-02 Lockheed Martin Corporation VCSEL array stimulator apparatus and method for light stimulation of bodily tissues
US8709078B1 (en) 2011-08-03 2014-04-29 Lockheed Martin Corporation Ocular implant with substantially constant retinal spacing for transmission of nerve-stimulation light
US8792978B2 (en) 2010-05-28 2014-07-29 Lockheed Martin Corporation Laser-based nerve stimulators for, E.G., hearing restoration in cochlear prostheses and method
US8956396B1 (en) 2005-10-24 2015-02-17 Lockheed Martin Corporation Eye-tracking visual prosthetic and method
US20080077200A1 (en) * 2006-09-21 2008-03-27 Aculight Corporation Apparatus and method for stimulation of nerves and automated control of surgical instruments
US8945197B1 (en) 2005-10-24 2015-02-03 Lockheed Martin Corporation Sight-restoring visual prosthetic and method using infrared nerve-stimulation light
US8012189B1 (en) 2007-01-11 2011-09-06 Lockheed Martin Corporation Method and vestibular implant using optical stimulation of nerves
US8929973B1 (en) 2005-10-24 2015-01-06 Lockheed Martin Corporation Apparatus and method for characterizing optical sources used with human and animal tissues
US8996131B1 (en) 2006-09-28 2015-03-31 Lockheed Martin Corporation Apparatus and method for managing chronic pain with infrared light sources and heat
US8498699B2 (en) * 2008-10-03 2013-07-30 Lockheed Martin Company Method and nerve stimulator using simultaneous electrical and optical signals
US7883536B1 (en) 2007-01-19 2011-02-08 Lockheed Martin Corporation Hybrid optical-electrical probes
JP2011501189A (ja) * 2007-10-25 2011-01-06 ザ・リサーチ・ファウンデーション・オブ・ステイト・ユニバーシティー・オブ・ニューヨーク 単一光子分光計
US9011508B2 (en) 2007-11-30 2015-04-21 Lockheed Martin Corporation Broad wavelength profile to homogenize the absorption profile in optical stimulation of nerves
US20090289833A1 (en) * 2008-05-23 2009-11-26 Johnson Paul A Sparse array millimeter wave imaging system
US20100016732A1 (en) * 2008-07-17 2010-01-21 Lockheed Martin Corporation Apparatus and method for neural-signal capture to drive neuroprostheses or control bodily function
WO2010040142A1 (en) 2008-10-03 2010-04-08 Lockheed Martin Corporation Nerve stimulator and method using simultaneous electrical and optical signals
WO2010092752A1 (ja) * 2009-02-10 2010-08-19 三井造船株式会社 蛍光検出装置及び蛍光検出方法
US8330123B2 (en) * 2010-01-28 2012-12-11 I.S.S. (Usa), Inc. System and method for digital parallel frequency fluorometry
DE102010019095B4 (de) * 2010-04-30 2016-12-08 Deutsches Zentrum für Luft- und Raumfahrt e.V. Verfahren und Vorrichtung zur Fluoreszenzlebensdauermessung
US7884933B1 (en) 2010-05-05 2011-02-08 Revolutionary Business Concepts, Inc. Apparatus and method for determining analyte concentrations
WO2012061584A2 (en) 2010-11-03 2012-05-10 University Of Washington Through Its Center For Commercialization Deternimation of tissue oxygenation in vivo
US9222888B2 (en) 2012-04-03 2015-12-29 Ut-Battelle, Llc Pulse amplitude modulated chlorophyll fluorometer
US11428786B2 (en) * 2017-12-03 2022-08-30 Munro Design & Technologies, Llc Dual waveforms for three-dimensional imaging systems and methods thereof
DE102022122092A1 (de) * 2022-08-31 2024-02-29 Pyroscience Gmbh Referenz-Messung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD242485A1 (de) * 1985-10-21 1987-01-28 Akad Wissenschaften Ddr Phasen- und modulationsgrad-fluorometer fuer die kurzzeitspektroskopie
DD245491A1 (de) * 1985-12-30 1987-05-06 Akad Wissenschaften Ddr Phasenempfindlicher fluoreszenzdetektor fuer die kurzzeitspektroskopie
US4840485A (en) * 1986-12-17 1989-06-20 I.S.S. (U.S.A.) Inc. Frequency domain cross-correlation fluorometry with phase-locked loop frequency synthesizers
US4937457A (en) * 1989-02-10 1990-06-26 Slm Instruments, Inc. Picosecond multi-harmonic fourier fluorometer
WO1990009637A1 (en) * 1989-02-13 1990-08-23 Research Corporation Technologies, Inc. Method and means for parallel frequency acquisition in frequency domain fluorometry
US5212386A (en) * 1991-12-13 1993-05-18 I.S.S. (U.S.A.) Inc. High speed cross-correlation frequency domain fluorometry-phosphorimetry

Also Published As

Publication number Publication date
EP0600633A2 (de) 1994-06-08
EP0600633A3 (en) 1994-06-15
JPH07306140A (ja) 1995-11-21
CA2103077A1 (en) 1994-06-02
DE69328762D1 (de) 2000-07-06
DE69328762T2 (de) 2001-02-22
US5323010A (en) 1994-06-21
EP0600633B1 (de) 2000-05-31

Similar Documents

Publication Publication Date Title
ATE193597T1 (de) Zeitaufgelöste optische sensorarrays und ccd- kameras zur frequenzbereich-fluorimetrie und/oder phosphorimetrie
KR100404961B1 (ko) 강도변조된복사전자기장의검출과복조를위한장치및그방법
GB1478062A (en) Method and apparatus for recognizing coloured pattern
KR840003359A (ko) 기판 피막의 불균일성 검출방법 및 장치
AU4976899A (en) Apparatus and method for measuring and imaging traveling waves
US5286968A (en) Method and device for multichannel analog detection
JPS5780546A (en) Detecting device for foreign substance
FR2442460A1 (fr) Dispositif de modulation optique
EP1136272A3 (de) Gerät und Verfahren zur Bildaufzeichnung
RU98107404A (ru) Способ бесконтактного измерения температуры
SU800705A1 (ru) Способ измерени температуры иуСТРОйСТВО дл ЕгО ОСущЕСТВлЕНи
RU2062445C1 (ru) Способ измерения структуры и динамики микрообъектов и устройство для его осуществления
NO913936D0 (no) Maaldetektor som eliminerer innenfor-rekkevidde foelsomhet
EP1298410A4 (de) Verfahren zur interferenzmessung und vorrichtung zur interferenzmessung
RU2016382C1 (ru) Оптико-электронное измерительное устройство
SU1139261A1 (ru) Устройство дл измерени скорости
JP2896547B2 (ja) 特定パルス光の受光強度の高増幅測定装置
SU1282008A1 (ru) Датчик скорости механизма транспортировани магнитного носител
RU1803747C (ru) Устройство дл бесконтактного измерени температуры
RU1778632C (ru) Способ контрол лучевой прочности оптических изделий и устройство дл его осуществлени
SU1134919A2 (ru) Устройство дл определени диаграммы направленности антенны
RU2073200C1 (ru) Оптико-электронное измерительное устройство
ATE310992T1 (de) Verbesserungen hinsichtlich mustererkennung
SU170838A1 (ru) Устройство для измерения оптических плотностей
SU1247671A1 (ru) Способ регистрации сигналов