ATE194353T1 - Antimikrobielle quinolonyllactamester - Google Patents
Antimikrobielle quinolonyllactamesterInfo
- Publication number
- ATE194353T1 ATE194353T1 AT89870152T AT89870152T ATE194353T1 AT E194353 T1 ATE194353 T1 AT E194353T1 AT 89870152 T AT89870152 T AT 89870152T AT 89870152 T AT89870152 T AT 89870152T AT E194353 T1 ATE194353 T1 AT E194353T1
- Authority
- AT
- Austria
- Prior art keywords
- antimicrobial
- lactam
- quinolonyllactamesters
- quinolone
- art
- Prior art date
Links
- 230000000845 anti-microbial effect Effects 0.000 title abstract 4
- 150000003951 lactams Chemical class 0.000 abstract 2
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical group C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- -1 lactam esters Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26179888A | 1988-10-24 | 1988-10-24 | |
| US41803389A | 1989-10-12 | 1989-10-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE194353T1 true ATE194353T1 (de) | 2000-07-15 |
Family
ID=26948845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89870152T ATE194353T1 (de) | 1988-10-24 | 1989-10-20 | Antimikrobielle quinolonyllactamester |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0366641B1 (de) |
| JP (1) | JPH03502933A (de) |
| KR (1) | KR0157297B1 (de) |
| AT (1) | ATE194353T1 (de) |
| AU (1) | AU635226B2 (de) |
| CA (1) | CA2001201C (de) |
| DE (1) | DE68929227T2 (de) |
| DK (1) | DK527489A (de) |
| ES (1) | ES2148135T3 (de) |
| GR (1) | GR3034367T3 (de) |
| NZ (1) | NZ231110A (de) |
| PH (1) | PH31375A (de) |
| SG (1) | SG67307A1 (de) |
| WO (1) | WO1990004594A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5147871A (en) * | 1986-07-03 | 1992-09-15 | Hoffmann La-Roche, Inc. | Anti-bacterial cephalosporin compounds |
| US5336768A (en) * | 1988-05-24 | 1994-08-09 | Hoffmann-La Roche Inc. | Antibacterial cephalosporin compounds |
| CS273349B2 (en) * | 1988-03-31 | 1991-03-12 | Hoffmann La Roche | Method of cephalosporin's new derivatives production |
| EP0997466A1 (de) * | 1988-10-24 | 2000-05-03 | PROCTER & GAMBLE PHARMACEUTICALS, INC. | Antimikrobielle Laktamchinolone |
| CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
| US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
| US5491139A (en) * | 1988-10-24 | 1996-02-13 | The Procter & Gamble Company | Antimicrobial quinolonyl lactams |
| US5159077A (en) * | 1989-07-21 | 1992-10-27 | Hoffmann-La Roche Inc. | Penam antibacterial compounds |
| US5162523A (en) * | 1989-07-21 | 1992-11-10 | Hoffmann-La Roche Inc. | Cephalosporin antibacterial compounds |
| AU636913B2 (en) * | 1989-10-11 | 1993-05-13 | Takeda Chemical Industries Ltd. | Tricyclic carbapenem compounds |
| ZA912279B (en) * | 1990-04-09 | 1992-02-26 | Hoffmann La Roche | Carbapenem compounds |
| DK0525057T3 (da) * | 1990-04-18 | 2000-07-31 | Procter & Gamble Pharma | Antimikrobielle quinolonyllactamer |
| WO1993007154A1 (en) * | 1991-10-01 | 1993-04-15 | Procter & Gamble Pharmaceuticals, Inc. | Process for making antimicrobial quinolonyl lactams |
| DE4234330A1 (de) * | 1992-10-12 | 1994-04-14 | Bayer Ag | Chinoloncarbonsäuren |
| EP0775145A1 (de) * | 1994-08-02 | 1997-05-28 | The Procter & Gamble Company | Verfahren zur herstellung von quinolonyl laktam antimikorbielle verbindungen und zwischenprodukte |
| EP0775114B1 (de) * | 1994-08-02 | 2000-03-22 | The Procter & Gamble Company | Verfahren zur herstellung von antimikrobiellen verbindungen |
| US9670179B1 (en) * | 2013-03-14 | 2017-06-06 | University Of South Florida | Antibiotic compositions and methods of use |
| CN105753887A (zh) * | 2016-02-05 | 2016-07-13 | 东南大学 | 一种具有喹诺酮和β-内酰胺结构的化合物及其合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4794109A (en) * | 1982-11-16 | 1988-12-27 | Ciba-Geigy Corporation | 6-hydroxy-lower alkylpenem compounds, pharmaceutical preparations that contain these compounds, and the use of the latter |
| GB2164334B (en) * | 1984-09-10 | 1988-08-03 | Hoechst Uk Ltd | Antibacterial 7-oxo-4-thia-1-azabicyclo 3,2,0 hept-2-ene derivativess |
| US4861768A (en) * | 1986-02-27 | 1989-08-29 | Taiho Pharmaceutical Company, Limited | 2 β-substituted thiomethylpenicillin derivatives and their preparation and use |
| ZA874696B (en) * | 1986-07-03 | 1988-01-04 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Acyl derivatives |
-
1989
- 1989-10-20 AT AT89870152T patent/ATE194353T1/de not_active IP Right Cessation
- 1989-10-20 DE DE68929227T patent/DE68929227T2/de not_active Expired - Fee Related
- 1989-10-20 ES ES89870152T patent/ES2148135T3/es not_active Expired - Lifetime
- 1989-10-20 SG SG1996003053A patent/SG67307A1/en unknown
- 1989-10-20 EP EP89870152A patent/EP0366641B1/de not_active Expired - Lifetime
- 1989-10-23 CA CA002001201A patent/CA2001201C/en not_active Expired - Fee Related
- 1989-10-24 NZ NZ231110A patent/NZ231110A/en unknown
- 1989-10-24 KR KR1019890015234A patent/KR0157297B1/ko not_active Expired - Fee Related
- 1989-10-24 WO PCT/US1989/004803 patent/WO1990004594A1/en not_active Ceased
- 1989-10-24 JP JP1511606A patent/JPH03502933A/ja active Pending
- 1989-10-24 DK DK527489A patent/DK527489A/da not_active Application Discontinuation
- 1989-10-24 PH PH39403A patent/PH31375A/en unknown
- 1989-10-24 AU AU43694/89A patent/AU635226B2/en not_active Ceased
-
2000
- 2000-09-08 GR GR20000402053T patent/GR3034367T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE68929227T2 (de) | 2001-05-31 |
| EP0366641A3 (de) | 1991-12-11 |
| NZ231110A (en) | 1992-06-25 |
| EP0366641B1 (de) | 2000-07-05 |
| HK1013984A1 (en) | 1999-09-17 |
| AU635226B2 (en) | 1993-03-18 |
| ES2148135T3 (es) | 2000-10-16 |
| KR900006343A (ko) | 1990-05-08 |
| JPH03502933A (ja) | 1991-07-04 |
| SG67307A1 (en) | 1999-09-21 |
| CA2001201C (en) | 1998-12-22 |
| DK527489D0 (da) | 1989-10-24 |
| DE68929227D1 (de) | 2000-08-10 |
| EP0366641A2 (de) | 1990-05-02 |
| GR3034367T3 (en) | 2000-12-29 |
| DK527489A (da) | 1990-04-25 |
| CA2001201A1 (en) | 1990-04-24 |
| PH31375A (en) | 1998-10-29 |
| KR0157297B1 (ko) | 1998-11-16 |
| AU4369489A (en) | 1990-05-03 |
| WO1990004594A1 (en) | 1990-05-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEFA | Change of the company name | ||
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |