ATE195339T1 - Antagonisten von wachstumshormonen - Google Patents

Antagonisten von wachstumshormonen

Info

Publication number: ATE195339T1
Authority: AT; Austria
Prior art keywords: antagonists; growth hormones; growth; animals; antagonist
Prior art date: 1989-10-12

Application number

AT90917592T

Other languages

English (en)

Inventor

John J Kopchick

Wen Y Chen

Original Assignee

Univ Ohio

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-12

Filing date

1990-10-12

Publication date

2000-08-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23662783&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE195339(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-10-12 Application filed by Univ Ohio filed Critical Univ Ohio

2000-08-15 Application granted granted Critical

2000-08-15 Publication of ATE195339T1 publication Critical patent/ATE195339T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Chemical & Material Sciences (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Environmental Sciences (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Biophysics (AREA)
General Engineering & Computer Science (AREA)
Biodiversity & Conservation Biology (AREA)
Endocrinology (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Wood Science & Technology (AREA)
Animal Husbandry (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT90917592T 1989-10-12 1990-10-12 Antagonisten von wachstumshormonen ATE195339T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US41956189A	1989-10-12	1989-10-12
PCT/US1990/005874 WO1991005853A1 (en)	1989-10-12	1990-10-12	Growth hormone antagonists

Publications (1)

Publication Number	Publication Date
ATE195339T1 true ATE195339T1 (de)	2000-08-15

Family

ID=23662783

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90917592T ATE195339T1 (de)	1989-10-12	1990-10-12	Antagonisten von wachstumshormonen

Country Status (10)

Country	Link
EP (1)	EP0556171B1 (de)
JP (1)	JP3789928B2 (de)
AT (1)	ATE195339T1 (de)
AU (1)	AU652545B2 (de)
CA (1)	CA2067136C (de)
DE (1)	DE69033603T2 (de)
DK (1)	DK0556171T3 (de)
ES (1)	ES2150901T3 (de)
GR (1)	GR3034743T3 (de)
WO (1)	WO1991005853A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991000870A1 (en) *	1989-07-10	1991-01-24	The Upjohn Company	Somatotropin analogs
US5350836A (en) *	1989-10-12	1994-09-27	Ohio University	Growth hormone antagonists
US5310882A (en) *	1990-11-30	1994-05-10	American Cyanamid Company	Somatotropins with alterations in the α-helix 3 region
CA2102129C (en) *	1991-05-01	2003-04-01	John J. Kopchick	Growth hormone antagonists
ATE196548T1 (de)	1991-05-10	2000-10-15	Genentech Inc	Auswählen von agonisten und antagonisten von liganden
US6429186B1 (en)	1991-05-10	2002-08-06	Genentech, Inc.	Ligand antagonists for treatment of breast cancer
US5684136A (en) *	1992-05-18	1997-11-04	Genentech, Inc.	Chimeric hepatocyte growth factor (HGF) ligand variants
CA2117893A1 (en) *	1992-05-18	1993-11-25	Paul J. Godowski	Variant dimers for receptor activation
AU3056099A (en) *	1998-04-04	1999-10-25	Nakoshi, Hideo	Method for searching physiologically active substances, process for producing theses substances and drugs found by the searching method
US7855279B2 (en)	2005-09-27	2010-12-21	Amunix Operating, Inc.	Unstructured recombinant polymers and uses thereof
US8680050B2 (en)	2009-02-03	2014-03-25	Amunix Operating Inc.	Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
US8703717B2 (en)	2009-02-03	2014-04-22	Amunix Operating Inc.	Growth hormone polypeptides and methods of making and using same
DK3178835T3 (da)	2009-02-03	2019-06-24	Amunix Pharmaceuticals Inc	Forlængede rekombinante polypeptider og sammensætninger omfattende samme
US9849188B2 (en)	2009-06-08	2017-12-26	Amunix Operating Inc.	Growth hormone polypeptides and methods of making and using same
US9181585B2 (en)	2009-09-17	2015-11-10	Cy O'connor Erade Village Foundation	Methods of genotyping livestock

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5010011A (en) *	1985-03-28	1991-04-23	Wisconsin Alumni Research Foundation	Bovine placental lactogen gene
AU613876B2 (en) *	1986-10-01	1991-08-15	Merck & Co., Inc.	Synthetic genes encoding proteins from plasmid containing eucaryotic secretory signal peptides and process for secreting encoded proteins
GB8718937D0 (en) *	1987-08-11	1987-09-16	Coopers Animal Health	Biologically active molecules
WO1991000870A1 (en) *	1989-07-10	1991-01-24	The Upjohn Company	Somatotropin analogs

1990
- 1990-10-12 AT AT90917592T patent/ATE195339T1/de not_active IP Right Cessation
- 1990-10-12 WO PCT/US1990/005874 patent/WO1991005853A1/en not_active Ceased
- 1990-10-12 DE DE69033603T patent/DE69033603T2/de not_active Expired - Lifetime
- 1990-10-12 ES ES90917592T patent/ES2150901T3/es not_active Expired - Lifetime
- 1990-10-12 CA CA002067136A patent/CA2067136C/en not_active Expired - Lifetime
- 1990-10-12 AU AU68783/91A patent/AU652545B2/en not_active Expired
- 1990-10-12 JP JP50038791A patent/JP3789928B2/ja not_active Expired - Lifetime
- 1990-10-12 DK DK90917592T patent/DK0556171T3/da active
- 1990-10-12 EP EP90917592A patent/EP0556171B1/de not_active Expired - Lifetime
2000
- 2000-11-02 GR GR20000402431T patent/GR3034743T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
WO1991005853A1 (en)	1991-05-02
DK0556171T3 (da)	2000-12-18
AU652545B2 (en)	1994-09-01
AU6878391A (en)	1991-05-16
DE69033603T2 (de)	2001-04-12
JPH05505518A (ja)	1993-08-19
EP0556171A4 (de)	1992-06-15
GR3034743T3 (en)	2001-02-28
CA2067136C (en)	2003-07-29
EP0556171B1 (de)	2000-08-09
CA2067136A1 (en)	1991-04-13
DE69033603D1 (de)	2000-09-14
EP0556171A1 (de)	1993-08-25
ES2150901T3 (es)	2000-12-16
JP3789928B2 (ja)	2006-06-28

Legal Events

Date	Code	Title	Description
2001-01-15	UEP	Publication of translation of european patent specification
2011-01-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
DE69033603D1 (de)	2000-09-14	Antagonisten von wachstumshormonen
DE68922602D1 (de)	1995-06-14	Polypeptide mit hormonwachstumsbefreiender wirkung.
IT9048315A0 (it)	1990-09-27	Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi.
DE3875782D1 (de)	1992-12-17	Leucotrien-antagonisten.
DE3884529D1 (de)	1993-11-04	Leader-anteile zur produktion von rekombinanten proteinen.
FI892135L (fi)	1989-05-03	Rekombinant antikropp.
DE3852383D1 (de)	1995-01-19	Gereinigtes follikel-stimulierendes hormon.
FI880751A7 (fi)	1988-08-19	Eläimiä karkoittava aineseos.
DE68908166D1 (de)	1993-09-09	Zuechtung von halbleiterkristall-materialien.
ES2023253B3 (es)	1992-01-01	Composiciones cementosas.
NO852568L (no)	1985-12-30	Fiskeveksthormon-polypeptid.
DK57289A (da)	1989-08-10	Dyreprotein
CA2102129A1 (en)	1992-11-02	Growth hormone antagonists
DE3881533D1 (de)	1993-07-15	Tiermedizinische zusammensetzung zur verhinderung von diarrhoe bei tieren.
DE3886517D1 (de)	1994-02-03	Menschlicher Prourokinase ähnliches Polypeptid.
DE3880520D1 (de)	1993-06-03	Rekombinantes plasmid fuer die expression von l-phenylalanin-ammonialyase und transformierte staemme, die es enthalten.
DE3853743D1 (de)	1995-06-14	Rekombinanter menschlicher ADF.
DE3875030D1 (de)	1992-11-05	Leukotrien-antagonisten.
FI884255A0 (fi)	1988-09-15	L-aspartyl-3-(bicykloalkyl)-l -alaninalkylestrar med hoeg soethetsgrad.
DK525787A (da)	1988-04-10	Polypeptidantagonister
DE68905343D1 (de)	1993-04-15	Dosisform zur verabreichung von calciumantagonisten.
FI884798A7 (fi)	1989-04-29	Rekombinantlymfotoxin.
DE69002383D1 (de)	1993-09-02	Zusammensetzung zur heilung von autoimmunkrankheiten.
IT8723080A0 (it)	1987-12-18	Componente d'arredamento, in particolare del tipo poltrona o simile.
DE68901439D1 (de)	1992-06-11	Gebaermutterhalsprothese.