ATE195349T1 - Enzymatisches verfahren zur herstellung von optisch-aktiven tetralin-derivaten - Google Patents
Enzymatisches verfahren zur herstellung von optisch-aktiven tetralin-derivatenInfo
- Publication number
- ATE195349T1 ATE195349T1 AT95400878T AT95400878T ATE195349T1 AT E195349 T1 ATE195349 T1 AT E195349T1 AT 95400878 T AT95400878 T AT 95400878T AT 95400878 T AT95400878 T AT 95400878T AT E195349 T1 ATE195349 T1 AT E195349T1
- Authority
- AT
- Austria
- Prior art keywords
- configuration
- acid
- enzymatic process
- producing optically
- ester
- Prior art date
Links
- 230000002255 enzymatic effect Effects 0.000 title 1
- CXWXQJXEFPUFDZ-UHFFFAOYSA-N tetralin Chemical class C1=CC=C2CCCCC2=C1 CXWXQJXEFPUFDZ-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- 150000002148 esters Chemical class 0.000 abstract 2
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 2
- NTAGXJQHJQUOOA-UHFFFAOYSA-N 1,2,3,4-tetrahydronaphthalene-2-carboxylic acid Chemical compound C1=CC=C2CC(C(=O)O)CCC2=C1 NTAGXJQHJQUOOA-UHFFFAOYSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004882 Lipase Human genes 0.000 abstract 1
- 108090001060 Lipase Proteins 0.000 abstract 1
- 239000004367 Lipase Substances 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 230000000415 inactivating effect Effects 0.000 abstract 1
- 235000019421 lipase Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/34—Unsaturated compounds containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/08—Saturated compounds containing ether groups, groups, groups, or groups
- C07C62/12—Saturated compounds containing ether groups, groups, groups, or groups polycyclic
- C07C62/14—Saturated compounds containing ether groups, groups, groups, or groups polycyclic having a carboxyl group on a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94400863A EP0678579A1 (de) | 1994-04-21 | 1994-04-21 | Enzymatisches Verfahren zur Herstellung von optisch-aktiven Tetralin-Derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE195349T1 true ATE195349T1 (de) | 2000-08-15 |
Family
ID=8217995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95400878T ATE195349T1 (de) | 1994-04-21 | 1995-04-20 | Enzymatisches verfahren zur herstellung von optisch-aktiven tetralin-derivaten |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US5573949A (de) |
| EP (1) | EP0678579A1 (de) |
| JP (1) | JPH0838193A (de) |
| AT (1) | ATE195349T1 (de) |
| DE (1) | DE69518274D1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19604191A1 (de) * | 1996-02-06 | 1997-08-07 | Hoechst Schering Agrevo Gmbh | 2,4-Diamino-1,3,5-triazine, Verfahren zu deren Herstellung und deren Verwendung als Herbizide und Pflanzenwachstumsregulatoren |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3345660A1 (de) * | 1983-12-16 | 1985-06-27 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur gewinnung von d(+)naproxen |
| EP0300404A3 (de) * | 1987-07-20 | 1990-07-18 | G.D. Searle & Co. | Di- und Tetrahydronaphthyl-Derivate als anti-allergische Wirkstoffe |
| IE65511B1 (en) * | 1989-12-29 | 1995-11-01 | Sanofi Sa | New phenylethanolaminomethyltetralins |
-
1994
- 1994-04-21 EP EP94400863A patent/EP0678579A1/de not_active Withdrawn
-
1995
- 1995-04-19 JP JP7093680A patent/JPH0838193A/ja not_active Withdrawn
- 1995-04-20 US US08/425,743 patent/US5573949A/en not_active Expired - Fee Related
- 1995-04-20 AT AT95400878T patent/ATE195349T1/de not_active IP Right Cessation
- 1995-04-20 DE DE69518274T patent/DE69518274D1/de not_active Expired - Lifetime
-
1996
- 1996-07-24 US US08/685,488 patent/US5719308A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0678579A1 (de) | 1995-10-25 |
| DE69518274D1 (de) | 2000-09-14 |
| US5719308A (en) | 1998-02-17 |
| JPH0838193A (ja) | 1996-02-13 |
| US5573949A (en) | 1996-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |