ATE196290T1 - Pyridin- und pyrazindicarbonsäurederivate als zellwachstumsregulatoren - Google Patents

Pyridin- und pyrazindicarbonsäurederivate als zellwachstumsregulatoren

Info

Publication number
ATE196290T1
ATE196290T1 AT95941202T AT95941202T ATE196290T1 AT E196290 T1 ATE196290 T1 AT E196290T1 AT 95941202 T AT95941202 T AT 95941202T AT 95941202 T AT95941202 T AT 95941202T AT E196290 T1 ATE196290 T1 AT E196290T1
Authority
AT
Austria
Prior art keywords
pyrazinecarbonic
pyridine
cell growth
acid derivatives
growth regulators
Prior art date
Application number
AT95941202T
Other languages
English (en)
Inventor
Jessie Sandosham
Johann Hiebl
Hermann Kollmann
Alan Cuthbertson
Peter Fischer
Michael Hartmann
Peter Kremminger
Franz Rovenszky
Mette Husbyn
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Application granted granted Critical
Publication of ATE196290T1 publication Critical patent/ATE196290T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT95941202T 1994-12-20 1995-12-20 Pyridin- und pyrazindicarbonsäurederivate als zellwachstumsregulatoren ATE196290T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9425730.0A GB9425730D0 (en) 1994-12-20 1994-12-20 Compounds
PCT/GB1995/002977 WO1996019457A1 (en) 1994-12-20 1995-12-20 Pyridine and pyrazinedicarboxylic-acid derivatives as cell proliferation regulators

Publications (1)

Publication Number Publication Date
ATE196290T1 true ATE196290T1 (de) 2000-09-15

Family

ID=10766245

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95941202T ATE196290T1 (de) 1994-12-20 1995-12-20 Pyridin- und pyrazindicarbonsäurederivate als zellwachstumsregulatoren

Country Status (8)

Country Link
US (2) US5972926A (de)
EP (1) EP0799208B1 (de)
AT (1) ATE196290T1 (de)
AU (1) AU4268696A (de)
DE (1) DE69518857T2 (de)
ES (1) ES2150021T3 (de)
GB (1) GB9425730D0 (de)
WO (1) WO1996019457A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9425730D0 (en) * 1994-12-20 1995-02-22 Nycomed Pharma As Compounds
EP0958283A1 (de) * 1997-01-27 1999-11-24 Nycomed Austria GmbH Neue verbindungen mit hämoregulatorischer wirkung
US6184241B1 (en) * 1998-08-24 2001-02-06 Kansas State University Research Foundation Aspartic protease inhibitors
US6340683B1 (en) 1999-04-22 2002-01-22 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (triazines)
US6989379B1 (en) 1999-04-22 2006-01-24 H. Lundbick A/S Selective NPY (Y5) antagonists
DK1183245T3 (da) 1999-04-22 2007-09-24 Lundbeck & Co As H Selektive NPY(Y5)-antagonister
US6218408B1 (en) 1999-06-30 2001-04-17 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (bicyclics)
US6222040B1 (en) 1999-06-30 2001-04-24 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (tricyclics)
US6225330B1 (en) 1999-06-30 2001-05-01 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (tricyclics)
US7273880B2 (en) 1999-06-30 2007-09-25 H. Lunbeck A/S Selective NPY (Y5) antagonists
US6214853B1 (en) 1999-06-30 2001-04-10 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (bicyclics)
FR2843590B1 (fr) 2002-08-14 2007-10-05 Prestwick Scient Capital Inc Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique
US20070270590A1 (en) * 2006-04-20 2007-11-22 Marioara Mendelovici Methods for preparing eszopiclone crystalline form a, substantially pure eszopiclone and optically enriched eszopiclone
US20080015197A1 (en) * 2006-06-26 2008-01-17 Alex Mainfeld Process for the preparatrion of zopiclone
TW200846340A (en) * 2007-01-31 2008-12-01 Teva Pharma Methods for preparing eszopiclone

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL104323A0 (en) * 1992-01-10 1993-05-13 Smithkline Beecham Corp Hemoregulatory peptides
GB9211677D0 (en) * 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
GB9211668D0 (en) * 1992-06-02 1992-07-15 Nycomed Bioreg As Peptide compounds
GB9314200D0 (en) * 1993-07-09 1993-08-18 Hafslund Nycomed As Peptide compounds
DE69420044T2 (de) * 1993-10-29 2000-03-23 Smithkline Beecham Corp., King Of Prussia Blutregulierende peptide
GB9324691D0 (en) * 1993-12-01 1994-01-19 Hafslund Nycomed As Peptide compounds
GB9425730D0 (en) * 1994-12-20 1995-02-22 Nycomed Pharma As Compounds

Also Published As

Publication number Publication date
WO1996019457A1 (en) 1996-06-27
GB9425730D0 (en) 1995-02-22
ES2150021T3 (es) 2000-11-16
US5972926A (en) 1999-10-26
EP0799208B1 (de) 2000-09-13
US6124298A (en) 2000-09-26
DE69518857D1 (de) 2000-10-19
AU4268696A (en) 1996-07-10
DE69518857T2 (de) 2001-04-26
EP0799208A1 (de) 1997-10-08

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